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Murcko scaffold

4-(4-Phenylpiperazin-1-yl)quinazoline scaffold

19 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
19
With full pages
1
Scaffold SMILES

c1ccc(N2CCN(c3ncnc4ccccc34)CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(4-Phenylpiperazin-1-yl)quinazoline page
Murcko scaffold c1ccc(N2CCN(c3ncnc4ccccc34)CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

4-(4-Phenylpiperazin-1-yl)quinazoline chemical structure, C18H18N4, CAS 26731-87-3
4-(4-Phenylpiperazin-1-yl)quinazoline
CAS 26731-87-3C18H18N4
4-[4-(2-Chlorophenyl)piperazino]-2-(methylsulfanyl)quinazoline chemical structure, C19H19ClN4S, CAS 866137-94-2
4-[4-(2-Chlorophenyl)piperazino]-2-(methylsulfanyl)quinazoline
CAS 866137-94-2C19H19ClN4S
4-[4-(2-Methoxyphenyl)piperazino]-2-(methylsulfanyl)quinazoline chemical structure, C20H22N4OS, CAS 866137-89-5
4-[4-(2-Methoxyphenyl)piperazino]-2-(methylsulfanyl)quinazoline
CAS 866137-89-5C20H22N4OS
4-[4-(2-Methoxyphenyl)piperazin-1-yl]quinazoline chemical structure, C19H20N4O, CAS 420837-22-5
4-[4-(2-Methoxyphenyl)piperazin-1-yl]quinazoline
CAS 420837-22-5C19H20N4O
6,7-Dimethoxy-4-(4-phenylpiperazin-1-yl)quinazoline chemical structure, C20H22N4O2, CAS 21584-80-5
6,7-Dimethoxy-4-(4-phenylpiperazin-1-yl)quinazoline
CAS 21584-80-5C20H22N4O2
4-[4-(3-Chlorophenyl)piperazin-1-yl]quinazoline chemical structure, C18H17ClN4, CAS 72700-43-7
4-[4-(3-Chlorophenyl)piperazin-1-yl]quinazoline
CAS 72700-43-7C18H17ClN4
4-[4-(3-Chlorophenyl)piperazin-1-yl]-6,7-dimethoxyquinazoline chemical structure, C20H21ClN4O2, CAS 167410-47-1
4-[4-(3-Chlorophenyl)piperazin-1-yl]-6,7-dimethoxyquinazoline
CAS 167410-47-1C20H21ClN4O2
4-[4-(4-Fluorophenyl)piperazin-1-yl]-6,7-dimethoxyquinazoline chemical structure, C20H21FN4O2, CAS 229476-62-4
4-[4-(4-Fluorophenyl)piperazin-1-yl]-6,7-dimethoxyquinazoline
CAS 229476-62-4C20H21FN4O2
6,7-Dimethoxy-4-[4-(3-methoxyphenyl)piperazin-1-yl]quinazoline chemical structure, C21H24N4O3, CAS 229476-66-8
6,7-Dimethoxy-4-[4-(3-methoxyphenyl)piperazin-1-yl]quinazoline
CAS 229476-66-8C21H24N4O3
7-Bromo-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinazoline chemical structure, C19H19BrN4O, CAS 1219542-20-7
7-Bromo-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinazoline
CAS 1219542-20-7C19H19BrN4O
6,7-Dimethoxy-4-[4-(4-methoxyphenyl)piperazin-1-yl]quinazoline chemical structure, C21H24N4O3, CAS 229476-67-9
6,7-Dimethoxy-4-[4-(4-methoxyphenyl)piperazin-1-yl]quinazoline
CAS 229476-67-9C21H24N4O3
7-Bromo-4-(4-(3-methoxyphenyl)piperazin-1-yl)quinazoline chemical structure, C19H19BrN4O, CAS 1219545-35-3
7-Bromo-4-(4-(3-methoxyphenyl)piperazin-1-yl)quinazoline
CAS 1219545-35-3C19H19BrN4O
6,7-Dimethoxy-4-(4-(2-methoxyphenyl)piperazin-1-yl)-2-propylquinazoline chemical structure, C24H30N4O3, CAS 1448676-52-5
6,7-Dimethoxy-4-(4-(2-methoxyphenyl)piperazin-1-yl)-2-propylquinazoline
CAS 1448676-52-5C24H30N4O3
6,7-Dimethoxy-4-(4-(2-methoxyphenyl)piperazin-1-yl)-2-vinylquinazoline chemical structure, C23H26N4O3, CAS 1448676-57-0
6,7-Dimethoxy-4-(4-(2-methoxyphenyl)piperazin-1-yl)-2-vinylquinazoline
CAS 1448676-57-0C23H26N4O3
2-Ethyl-6,7-dimethoxy-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazoline chemical structure, C23H28N4O3, CAS 1448676-50-3
2-Ethyl-6,7-dimethoxy-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazoline
CAS 1448676-50-3C23H28N4O3
6-Chloro-4-[4-(2,5-dimethylphenyl)piperazin-1-yl]quinazoline chemical structure, C20H21ClN4, CAS 1661001-41-7
6-Chloro-4-[4-(2,5-dimethylphenyl)piperazin-1-yl]quinazoline
CAS 1661001-41-7C20H21ClN4
4-[4-(Quinazolin-4-yl)piperazin-1-yl]benzene-1-sulfonamide chemical structure, C18H19N5O2S, CAS 3054620-51-5
4-[4-(Quinazolin-4-yl)piperazin-1-yl]benzene-1-sulfonamide
CAS 3054620-51-5C18H19N5O2S
4-[4-(7-Fluoroquinazolin-4-yl)piperazin-1-yl]benzene-1-sulfonamide chemical structure, C18H18FN5O2S, CAS 3054415-77-6
4-[4-(7-Fluoroquinazolin-4-yl)piperazin-1-yl]benzene-1-sulfonamide
CAS 3054415-77-6C18H18FN5O2S
4-[4-(6-Fluoroquinazolin-4-yl)piperazin-1-yl]benzene-1-sulfonamide chemical structure, C18H18FN5O2S, CAS 3054547-43-9
4-[4-(6-Fluoroquinazolin-4-yl)piperazin-1-yl]benzene-1-sulfonamide
CAS 3054547-43-9C18H18FN5O2S