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Murcko scaffold

Ring system with 4 rings and 23 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
10
With full pages
3
Scaffold SMILES

O=c1[nH]nc(-c2ccc(N3CCCCC3)cc2)c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]nc(-c2ccc(N3CCCCC3)cc2)c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-[5-(3-Methyl-4-oxophthalazin-1-yl)-2-piperidin-1-ylphenyl]acetamide chemical structure, C22H24N4O2, CAS 685131-87-7
N-[5-(3-Methyl-4-oxophthalazin-1-yl)-2-piperidin-1-ylphenyl]acetamide
CAS 685131-87-7C22H24N4O2
N-[5-(3-Methyl-4-oxophthalazin-1-yl)-2-piperidin-1-ylphenyl]butanamide chemical structure, C24H28N4O2, CAS 685131-89-9
N-[5-(3-Methyl-4-oxophthalazin-1-yl)-2-piperidin-1-ylphenyl]butanamide
CAS 685131-89-9C24H28N4O2
N-[5-(3-Methyl-4-oxophthalazin-1-yl)-2-piperidin-1-ylphenyl]methanesulfonamide chemical structure, C21H24N4O3S, CAS 685131-98-0
N-[5-(3-Methyl-4-oxophthalazin-1-yl)-2-piperidin-1-ylphenyl]methanesulfonamide
CAS 685131-98-0C21H24N4O3S
4-[3-Nitro-4-(piperidin-1-yl)phenyl]-1,2-dihydrophthalazin-1-one chemical structure, C19H18N4O3, CAS 218144-45-7
4-[3-Nitro-4-(piperidin-1-yl)phenyl]-1,2-dihydrophthalazin-1-one
CAS 218144-45-7C19H18N4O3
2-Methyl-4-(3-nitro-4-piperidin-1-ylphenyl)phthalazin-1-one chemical structure, C20H20N4O3, CAS 684235-19-6
2-Methyl-4-(3-nitro-4-piperidin-1-ylphenyl)phthalazin-1-one
CAS 684235-19-6C20H20N4O3
2-Methyl-4-[4-(4-methylpiperidin-1-yl)-3-nitrophenyl]phthalazin-1-one chemical structure, C21H22N4O3, CAS 578697-62-8
2-Methyl-4-[4-(4-methylpiperidin-1-yl)-3-nitrophenyl]phthalazin-1-one
CAS 578697-62-8C21H22N4O3
4-[4-(4-Methylpiperidin-1-yl)-3-nitrophenyl]-1,2-dihydrophthalazin-1-one chemical structure, C20H20N4O3, CAS 575460-40-1
4-[4-(4-Methylpiperidin-1-yl)-3-nitrophenyl]-1,2-dihydrophthalazin-1-one
CAS 575460-40-1C20H20N4O3
4-[4-(2-Ethylpiperidin-1-yl)-3-nitrophenyl]-1,2-dihydrophthalazin-1-one chemical structure, C21H22N4O3, CAS 882000-12-6
4-[4-(2-Ethylpiperidin-1-yl)-3-nitrophenyl]-1,2-dihydrophthalazin-1-one
CAS 882000-12-6C21H22N4O3
4-[3-Nitro-4-(4-propylpiperidin-1-yl)phenyl]-1,2-dihydrophthalazin-1-one chemical structure, C22H24N4O3, CAS 882000-13-7
4-[3-Nitro-4-(4-propylpiperidin-1-yl)phenyl]-1,2-dihydrophthalazin-1-one
CAS 882000-13-7C22H24N4O3
4-[4-(3-Methylpiperidin-1-yl)-3-nitrophenyl]-1,2-dihydrophthalazin-1-one chemical structure, C20H20N4O3, CAS 882000-14-8
4-[4-(3-Methylpiperidin-1-yl)-3-nitrophenyl]-1,2-dihydrophthalazin-1-one
CAS 882000-14-8C20H20N4O3