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Murcko scaffold

Ring system with 3 rings and 22 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
10
With full pages
2
Scaffold SMILES

O=C(Nc1cccs1)c1ccc(S(=O)(=O)N2CCCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cccs1)c1ccc(S(=O)(=O)N2CCCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Diethyl 3-methyl-5-(4-(pyrrolidin-1-ylsulfonyl)benzamido)thiophene-2,4-dicarboxylate chemical structure, C22H26N2O7S2, CAS 325694-41-5
Diethyl 3-methyl-5-(4-(pyrrolidin-1-ylsulfonyl)benzamido)thiophene-2,4-dicarboxylate
CAS 325694-41-5C22H26N2O7S2
Ethyl 5-nitro-2-[(4-pyrrolidin-1-ylsulfonylbenzoyl)amino]thiophene-3-carboxylate chemical structure, C18H19N3O7S2, CAS 397279-00-4
Ethyl 5-nitro-2-[(4-pyrrolidin-1-ylsulfonylbenzoyl)amino]thiophene-3-carboxylate
CAS 397279-00-4C18H19N3O7S2
2-(4-(Pyrrolidin-1-ylsulfonyl)benzamido)thiophene-3-carboxamide chemical structure, C16H17N3O4S2, CAS 864940-64-7
2-(4-(Pyrrolidin-1-ylsulfonyl)benzamido)thiophene-3-carboxamide
CAS 864940-64-7C16H17N3O4S2
N-Methyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)thiophene-3-carboxamide chemical structure, C17H19N3O4S2, CAS 888413-27-2
N-Methyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)thiophene-3-carboxamide
CAS 888413-27-2C17H19N3O4S2
N-(3-Cyanothiophen-2-yl)-4-(pyrrolidine-1-sulfonyl)benzamide chemical structure, C16H15N3O3S2, CAS 924157-55-1
N-(3-Cyanothiophen-2-yl)-4-(pyrrolidine-1-sulfonyl)benzamide
CAS 924157-55-1C16H15N3O3S2
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-4-pyrrolidin-1-ylsulfonylbenzamide chemical structure, C18H19N3O3S2, CAS 896301-45-4
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-4-pyrrolidin-1-ylsulfonylbenzamide
CAS 896301-45-4C18H19N3O3S2
4,5-Dimethyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)thiophene-3-carboxamide chemical structure, C18H21N3O4S2, CAS 896307-26-9
4,5-Dimethyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)thiophene-3-carboxamide
CAS 896307-26-9C18H21N3O4S2
N-(3-(2,2-Dimethylhydrazinecarbonyl)thiophen-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C18H22N4O4S2, CAS 893128-66-0
N-(3-(2,2-Dimethylhydrazinecarbonyl)thiophen-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 893128-66-0C18H22N4O4S2
Methyl 4,5-dimethyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)thiophene-3-carboxylate chemical structure, C19H22N2O5S2, CAS 896615-24-0
Methyl 4,5-dimethyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)thiophene-3-carboxylate
CAS 896615-24-0C19H22N2O5S2
Orb1687302 chemical structure, C19H21N3O6S2, CAS 920459-41-2
Orb1687302
CAS 920459-41-2C19H21N3O6S2