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Murcko scaffold

4-(Pyrrolidin-1-ylsulfonyl)-N-(1,3,4-thiadiazol-2-yl)benzamide scaffold

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
9
With full pages
1
Scaffold SMILES

O=C(Nc1nncs1)c1ccc(S(=O)(=O)N2CCCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Pyrrolidin-1-ylsulfonyl)-N-(1,3,4-thiadiazol-2-yl)benzamide page
Murcko scaffold O=C(Nc1nncs1)c1ccc(S(=O)(=O)N2CCCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C15H18N4O3S2, CAS 577752-93-3
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 577752-93-3C15H18N4O3S2
N-(5-Prop-2-enylsulfanyl-1,3,4-thiadiazol-2-yl)-4-pyrrolidin-1-ylsulfonylbenzamide chemical structure, C16H18N4O3S3, CAS 637326-26-2
N-(5-Prop-2-enylsulfanyl-1,3,4-thiadiazol-2-yl)-4-pyrrolidin-1-ylsulfonylbenzamide
CAS 637326-26-2C16H18N4O3S3
N-(5-(Ethylthio)-1,3,4-thiadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C15H18N4O3S3, CAS 392239-67-7
N-(5-(Ethylthio)-1,3,4-thiadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 392239-67-7C15H18N4O3S3
Ethyl 2-((5-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-1,3,4-thiadiazol-2-yl)thio)acetate chemical structure, C17H20N4O5S3, CAS 392318-72-8
Ethyl 2-((5-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-1,3,4-thiadiazol-2-yl)thio)acetate
CAS 392318-72-8C17H20N4O5S3
N-(5-Methylsulfanyl-1,3,4-thiadiazol-2-yl)-4-pyrrolidin-1-ylsulfonylbenzamide chemical structure, C14H16N4O3S3, CAS 393572-56-0
N-(5-Methylsulfanyl-1,3,4-thiadiazol-2-yl)-4-pyrrolidin-1-ylsulfonylbenzamide
CAS 393572-56-0C14H16N4O3S3
N-(5-(Propylthio)-1,3,4-thiadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C16H20N4O3S3, CAS 393572-57-1
N-(5-(Propylthio)-1,3,4-thiadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 393572-57-1C16H20N4O3S3
N-(5-Methyl-1,3,4-thiadiazol-2-yl)-4-pyrrolidin-1-ylsulfonylbenzamide chemical structure, C14H16N4O3S2, CAS 881933-20-6
N-(5-Methyl-1,3,4-thiadiazol-2-yl)-4-pyrrolidin-1-ylsulfonylbenzamide
CAS 881933-20-6C14H16N4O3S2
4-(Pyrrolidin-1-ylsulfonyl)-N-(1,3,4-thiadiazol-2-yl)benzamide chemical structure, C13H14N4O3S2, CAS 898656-72-9
4-(Pyrrolidin-1-ylsulfonyl)-N-(1,3,4-thiadiazol-2-yl)benzamide
CAS 898656-72-9C13H14N4O3S2
N-(5-((2-Amino-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C15H17N5O4S3, CAS 868974-89-4
N-(5-((2-Amino-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 868974-89-4C15H17N5O4S3