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Murcko scaffold

1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-phenoxyethanone scaffold

16 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
16
With full pages
7
Scaffold SMILES

O=C(COc1ccccc1)N1CCN(Cc2ccc3c(c2)OCO3)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-phenoxyethanone page
Murcko scaffold O=C(COc1ccccc1)N1CCN(Cc2ccc3c(c2)OCO3)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

Fipexide chemical structure, C20H21ClN2O4, CAS 34161-24-5
Fipexide
CAS 34161-24-5C20H21ClN2O4
Fipexide hydrochloride chemical structure, C20H22Cl2N2O4, CAS 34161-23-4
Fipexide hydrochloride
CAS 34161-23-4C20H22Cl2N2O4
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(2-bromo-4-ethylphenoxy)ethanone chemical structure, C22H25BrN2O4, CAS 667879-00-7
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(2-bromo-4-ethylphenoxy)ethanone
CAS 667879-00-7C22H25BrN2O4
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(4-methylphenoxy)ethanone chemical structure, C21H24N2O4, CAS 462602-96-6
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(4-methylphenoxy)ethanone
CAS 462602-96-6C21H24N2O4
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(3,4-dimethylphenoxy)ethanone chemical structure, C22H26N2O4, CAS 432495-42-6
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(3,4-dimethylphenoxy)ethanone
CAS 432495-42-6C22H26N2O4
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(4-methoxyphenoxy)ethanone chemical structure, C21H24N2O5, CAS 34161-27-8
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(4-methoxyphenoxy)ethanone
CAS 34161-27-8C21H24N2O5
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(2,5-dimethylphenoxy)ethanone chemical structure, C22H26N2O4, CAS 683804-93-5
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(2,5-dimethylphenoxy)ethanone
CAS 683804-93-5C22H26N2O4
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-phenoxyethanone chemical structure, C20H22N2O4, CAS 333780-49-7
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-phenoxyethanone
CAS 333780-49-7C20H22N2O4
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(4-chlorophenoxy)-2-methylpropan-1-one chemical structure, C22H25ClN2O4, CAS 599153-11-4
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(4-chlorophenoxy)-2-methylpropan-1-one
CAS 599153-11-4C22H25ClN2O4
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(2-bromo-4-propan-2-ylphenoxy)ethanone chemical structure, C23H27BrN2O4, CAS 693813-40-0
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(2-bromo-4-propan-2-ylphenoxy)ethanone
CAS 693813-40-0C23H27BrN2O4
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(4-bromophenoxy)ethanone chemical structure, C20H21BrN2O4, CAS 423741-31-5
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(4-bromophenoxy)ethanone
CAS 423741-31-5C20H21BrN2O4
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(4-bromo-2-chlorophenoxy)ethanone chemical structure, C20H20BrClN2O4, CAS 462082-55-9
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(4-bromo-2-chlorophenoxy)ethanone
CAS 462082-55-9C20H20BrClN2O4
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(4-propan-2-ylphenoxy)ethanone chemical structure, C23H28N2O4, CAS 432527-56-5
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(4-propan-2-ylphenoxy)ethanone
CAS 432527-56-5C23H28N2O4
4-[2-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-oxoethoxy]benzonitrile chemical structure, C21H21N3O4, CAS 924069-79-4
4-[2-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-oxoethoxy]benzonitrile
CAS 924069-79-4C21H21N3O4
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(4-methoxyphenoxy)propan-1-one chemical structure, C22H26N2O5, CAS 701230-01-5
1-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(4-methoxyphenoxy)propan-1-one
CAS 701230-01-5C22H26N2O5
4-[2-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-oxoethoxy]-N-propylbenzenesulfonamide chemical structure, C23H29N3O6S, CAS 701287-38-9
4-[2-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-2-oxoethoxy]-N-propylbenzenesulfonamide
CAS 701287-38-9C23H29N3O6S