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Murcko scaffold

Ring system with 2 rings and 16 atoms

6 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
6
With full pages
5
Scaffold SMILES

O=c1ccnc(SCCc2ccccc2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccnc(SCCc2ccccc2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

2-[(2-{4-Nitrophenyl}ethyl)sulfanyl]-3-methyl-4(3H)-pyrimidinone chemical structure, C13H13N3O3S, CAS 343346-79-2
2-[(2-{4-Nitrophenyl}ethyl)sulfanyl]-3-methyl-4(3H)-pyrimidinone
CAS 343346-79-2C13H13N3O3S
2-[(2-{4-Nitrophenyl}ethyl)sulfanyl]-4(3H)-pyrimidinone chemical structure, C12H11N3O3S, CAS 169557-01-1
2-[(2-{4-Nitrophenyl}ethyl)sulfanyl]-4(3H)-pyrimidinone
CAS 169557-01-1C12H11N3O3S
6-Methyl-2-phenethylsulfanyl-1H-pyrimidin-4-one chemical structure, C13H14N2OS, CAS 5627-44-1
6-Methyl-2-phenethylsulfanyl-1H-pyrimidin-4-one
CAS 5627-44-1C13H14N2OS
5-Ethyl-6-methyl-2-(phenethylthio)pyrimidin-4(3H)-one chemical structure, C15H18N2OS, CAS 516460-95-0
5-Ethyl-6-methyl-2-(phenethylthio)pyrimidin-4(3H)-one
CAS 516460-95-0C15H18N2OS
6-Ethyl-2-(phenethylthio)pyrimidin-4(3H)-one chemical structure, C14H16N2OS, CAS 899743-94-3
6-Ethyl-2-(phenethylthio)pyrimidin-4(3H)-one
CAS 899743-94-3C14H16N2OS
5,6-Dimethyl-2-(phenethylthio)pyrimidin-4(3H)-one chemical structure, C14H16N2OS, CAS 899991-11-8
5,6-Dimethyl-2-(phenethylthio)pyrimidin-4(3H)-one
CAS 899991-11-8C14H16N2OS