Murcko scaffold
Bicyclo(1.1.0)butane scaffold
57 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 4
- Chemicals
- 57
- With full pages
- 8
Scaffold SMILES
C1C2CC12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 57 chemicals
Bicyclo(1.1.0)butane
CAS 157-33-5C4H6
1,3-Dimethylbicyclo(1.1.0)butane
CAS 930-25-6C6H10
Bicyclo(1.1.0)butane-1-carboxcylic acid methyl ester
CAS 4935-01-7C6H8O2
![Bicyclo[1.1.0]butane-1-carbonitrile chemical structure, C5H5N, CAS 16955-35-4](/s/BPPMXXJOMACYJD-UHFFFAOYSA-N.svg)
Bicyclo[1.1.0]butane-1-carbonitrile
CAS 16955-35-4C5H5N
![1,2,2,3-Tetramethylbicyclo[1.1.0]butane chemical structure, C8H14, CAS 32348-64-4](/s/LRVMJLBNZZZECX-UHFFFAOYSA-N.svg)
1,2,2,3-Tetramethylbicyclo[1.1.0]butane
CAS 32348-64-4C8H14
![Methyl 2,2,4,4-tetramethylbicyclo[1.1.0]butane-3-carboxylate chemical structure, C10H16O2, CAS 19931-20-5](/s/ZBBOKFDBNDFUFS-UHFFFAOYSA-N.svg)
Methyl 2,2,4,4-tetramethylbicyclo[1.1.0]butane-3-carboxylate
CAS 19931-20-5C10H16O2
![Bicyclo[1.1.0]butane, 1-methyl- chemical structure, C5H8, CAS 30494-08-7](/s/XWWLRTHZWLTSNA-UHFFFAOYSA-N.svg)
Bicyclo[1.1.0]butane, 1-methyl-
CAS 30494-08-7C5H8
Bicyclo(1.1.0)butane, 1-bromo-
CAS 101391-44-0C4H5Br
![3-(Hydroxymethyl)bicyclo[1.1.0]butane-1-carbonitrile chemical structure, C6H7NO, CAS 175881-31-9](/s/GQJXJUSWDVNOAN-UHFFFAOYSA-N.svg)
3-(Hydroxymethyl)bicyclo[1.1.0]butane-1-carbonitrile
CAS 175881-31-9C6H7NO
Methyl 3-(hydroxymethyl)bicyclo(1.1.0)butane-1-carboxylate
CAS 175881-32-0C7H10O3
![3-(Bromomethyl)bicyclo[1.1.0]butane-1-carbonitrile chemical structure, C6H6BrN, CAS 566152-35-0](/s/WWQJBSVCUBKRKG-UHFFFAOYSA-N.svg)
3-(Bromomethyl)bicyclo[1.1.0]butane-1-carbonitrile
CAS 566152-35-0C6H6BrN
![2-[(3-Cyanobicyclo[1.1.0]but-1-yl)methyl]propanedinitrile chemical structure, C9H7N3, CAS 872988-60-8](/s/AMSFXWRXOFWYQJ-UHFFFAOYSA-N.svg)
2-[(3-Cyanobicyclo[1.1.0]but-1-yl)methyl]propanedinitrile
CAS 872988-60-8C9H7N3
2,2,4,4-Tetramethylbicyclo(1.1.0)butane
CAS 30494-12-3C8H14
![3-Methylbicyclo[1.1.0]butane-1-carbonitrile chemical structure, C6H7N, CAS 694-25-7](/s/OWNDZBODIXJTBD-UHFFFAOYSA-N.svg)
3-Methylbicyclo[1.1.0]butane-1-carbonitrile
CAS 694-25-7C6H7N
![Methyl 3-methylbicyclo[1.1.0]butane-1-carboxylate chemical structure, C7H10O2, CAS 30493-92-6](/s/QXALAIGMJXVFPB-UHFFFAOYSA-N.svg)
Methyl 3-methylbicyclo[1.1.0]butane-1-carboxylate
CAS 30493-92-6C7H10O2
![Bicyclo[1.1.0]butane-2,4-dicarbaldehyde chemical structure, C6H6O2, CAS 90242-00-5](/s/LNHQHOHFEPAWGT-UHFFFAOYSA-N.svg)
Bicyclo[1.1.0]butane-2,4-dicarbaldehyde
CAS 90242-00-5C6H6O2
![3-Methylbicyclo[1.1.0]butane-1-carboxamide chemical structure, C6H9NO, CAS 822-76-4](/s/ZQYACMFYTINNJO-UHFFFAOYSA-N.svg)
3-Methylbicyclo[1.1.0]butane-1-carboxamide
CAS 822-76-4C6H9NO
![Ethyl bicyclo[1.1.0]butane-1-carboxylate chemical structure, C7H10O2, CAS 29820-55-1](/s/FGTIQKGKVZKRJL-UHFFFAOYSA-N.svg)
Ethyl bicyclo[1.1.0]butane-1-carboxylate
CAS 29820-55-1C7H10O2
![3-Chlorobicyclo[1.1.0]butane-1-carbonitrile chemical structure, C5H4ClN, CAS 23745-75-7](/s/OVSLTIVJEFPORJ-UHFFFAOYSA-N.svg)
3-Chlorobicyclo[1.1.0]butane-1-carbonitrile
CAS 23745-75-7C5H4ClN
![3-Bromobicyclo[1.1.0]butane-1-carbonitrile chemical structure, C5H4BrN, CAS 87712-20-7](/s/WTFNJIXZXXCFCJ-UHFFFAOYSA-N.svg)
3-Bromobicyclo[1.1.0]butane-1-carbonitrile
CAS 87712-20-7C5H4BrN
![3-Ethenylbicyclo[1.1.0]butane-1-carbonitrile chemical structure, C7H7N, CAS 51934-08-8](/s/QMQVNQZLXDMMMS-UHFFFAOYSA-N.svg)
3-Ethenylbicyclo[1.1.0]butane-1-carbonitrile
CAS 51934-08-8C7H7N
![1-Bromo-2-methylbicyclo[1.1.0]butane chemical structure, C5H7Br, CAS 101391-45-1](/s/DQCDJUYRKLRESB-UHFFFAOYSA-N.svg)
1-Bromo-2-methylbicyclo[1.1.0]butane
CAS 101391-45-1C5H7Br
![1,2,2,3,4,4-Hexamethylbicyclo[1.1.0]butane chemical structure, C10H18, CAS 20019-13-0](/s/HFFRNFPLXRFOCT-UHFFFAOYSA-N.svg)
1,2,2,3,4,4-Hexamethylbicyclo[1.1.0]butane
CAS 20019-13-0C10H18
![1-(Bicyclo[1.1.0]butan-1-yl)ethanone chemical structure, C6H8O, CAS 24464-70-8](/s/DGRZPPHVKBCZBG-UHFFFAOYSA-N.svg)
1-(Bicyclo[1.1.0]butan-1-yl)ethanone
CAS 24464-70-8C6H8O
- tert-Butyl 3-methylbicyclo[1.1.0]butane-1-carboxylate30493-93-7C10H16O2
- Bicyclo(1.1.0)butane-1-carboxylic acid30493-99-3C5H6O2
- Bicyclo[1.1.0]butan-1-ylmethanol4935-02-8C5H8O
- Methyl 3-(bromomethyl)bicyclo[1.1.0]butane-1-carboxylate566152-37-2C7H9BrO2
- Bicyclo[1.1.0]butane-1,3-dicarboxylic acid37525-84-1C6H6O4
- 3-Carbamoylbicyclo[1.1.0]butane-1-carboxylic acid61168-43-2C6H7NO3
- 1 suppliersSodium bicyclo(1.1.0)butane-1-carboxylate2708281-46-1C5H5NaO2
- Bicyclo[1.1.0]butane-1,3-dicarboxamide37525-85-2C6H8N2O2
- Propan-2-yl bicyclo[1.1.0]butane-1-carboxylate129847-28-5C8H12O2
- Bicyclo[1.1.0]butane-1-carboxamide30494-00-9C5H7NO
- {3-Methylbicyclo[1.1.0]butan-1-yl}methanamine4839-70-7C6H11N
- Bicyclo[1.1.0]butan-1-amine72540-66-0C4H7N
- Hexafluorobicyclo(1.1.0)butane94024-64-3C4F6
- 1-Nitrosobicyclo[1.1.0]butane104835-36-1C4H5NO
- Bicyclo[1.1.0]butane-1,3-dicarbonitrile27184-67-4C6H4N2
- Trimethyl bicyclo[1.1.0]butane-1,2,2-tricarboxylate64374-69-2C10H12O6
- Bicyclo[1.1.0]butane-1,3-dicarboxylic acid, monomethyl ester61168-44-3C7H7O4-
- 2,2-Dichlorobicyclo[1.1.0]butane848171-76-6C4H4Cl2
- Bicyclo[1.1.0]butan-2-amine616215-75-9C4H7N
- 1-Ethyl-2,2,4-trimethylbicyclo[1.1.0]butane30541-57-2C9H16
- 1,3-Dimethyl bicyclo[1.1.0]butane-1,3-dicarboxylate23745-74-6C8H10O4
- Potassium bicyclo[1.1.0]butane-1-carboxylate1955548-10-3C5H5KO2
- tert-Butyl bicyclo(1.1.0)butane-1-carboxylate30493-94-8C9H14O2
- 3-Methylbicyclo[1.1.0]butane-1-carboxylic acid2932441-51-3C6H8O2
Related scaffolds
Same ring framework with different atoms or bond orders
