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Murcko scaffold

Ring system with 3 rings and 30 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
30
Chemicals
13
With full pages
1
Scaffold SMILES

O=C(CN=Nc1ccccc1)Nc1ccc(NC(=O)CN=Nc2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CN=Nc1ccccc1)Nc1ccc(NC(=O)CN=Nc2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

1,2-Benzenedicarboxylic acid, 3,3'-[(2,5-dichloro-1,4-phenylene)bis[imino(1-acetyl-2-oxo-2,1-ethanediyl)-2,1-diazenediyl]]bis- chemical structure, C30H22Cl2N6O12, CAS 57532-26-0
1,2-Benzenedicarboxylic acid, 3,3'-[(2,5-dichloro-1,4-phenylene)bis[imino(1-acetyl-2-oxo-2,1-ethanediyl)-2,1-diazenediyl]]bis-
CAS 57532-26-0C30H22Cl2N6O12
1,4-Benzenedicarboxylic acid, 2,2'-[1,4-phenylenebis[imino(1-acetyl-2-oxo-2,1-ethanediyl)-2,1-diazenediyl]]bis-, 1,1',4,4'-tetramethyl ester chemical structure, C34H32N6O12, CAS 68516-73-4
1,4-Benzenedicarboxylic acid, 2,2'-[1,4-phenylenebis[imino(1-acetyl-2-oxo-2,1-ethanediyl)-2,1-diazenediyl]]bis-, 1,1',4,4'-tetramethyl ester
CAS 68516-73-4C34H32N6O12
Butanamide, N,N'-(2,5-dimethyl-1,4-phenylene)bis[2-[2-(2,4-dichlorophenyl)diazenyl]-3-oxo- chemical structure, C28H24Cl4N6O4, CAS 74620-20-5
Butanamide, N,N'-(2,5-dimethyl-1,4-phenylene)bis[2-[2-(2,4-dichlorophenyl)diazenyl]-3-oxo-
CAS 74620-20-5C28H24Cl4N6O4
1,4-Dimethyl 2-(2-(1-(((4-((2-(2-(2-(methoxycarbonyl)phenyl)diazenyl)-1,3-dioxobutyl)amino)phenyl)amino)carbonyl)-2-oxopropyl)diazenyl)-1,4-benzenedicarboxylate chemical structure, C32H30N6O10, CAS 79102-66-2
1,4-Dimethyl 2-(2-(1-(((4-((2-(2-(2-(methoxycarbonyl)phenyl)diazenyl)-1,3-dioxobutyl)amino)phenyl)amino)carbonyl)-2-oxopropyl)diazenyl)-1,4-benzenedicarboxylate
CAS 79102-66-2C32H30N6O10
3,3'-((2,5-Dimethylbenzene-1,4-diyl)bis(imino(1,3-dioxobutane-1,2-diyl)diazene-2,1-diyl))bis(4-chlorobenzoic acid) chemical structure, C30H26Cl2N6O8, CAS 74351-78-3
3,3'-((2,5-Dimethylbenzene-1,4-diyl)bis(imino(1,3-dioxobutane-1,2-diyl)diazene-2,1-diyl))bis(4-chlorobenzoic acid)
CAS 74351-78-3C30H26Cl2N6O8
3-[[1-[4-[[2-[(5-Carboxy-2-chlorophenyl)diazenyl]-3-oxobutanoyl]amino]-5-chloro-2-methylanilino]-1,3-dioxobutan-2-yl]diazenyl]-4-chlorobenzoic acid chemical structure, C29H23Cl3N6O8, CAS 60728-43-0
3-[[1-[4-[[2-[(5-Carboxy-2-chlorophenyl)diazenyl]-3-oxobutanoyl]amino]-5-chloro-2-methylanilino]-1,3-dioxobutan-2-yl]diazenyl]-4-chlorobenzoic acid
CAS 60728-43-0C29H23Cl3N6O8
3-[[1-[4-[[2-[(5-Carboxy-2-chlorophenyl)diazenyl]-3-oxobutanoyl]amino]-2,5-dichloroanilino]-1,3-dioxobutan-2-yl]diazenyl]-4-chlorobenzoic acid chemical structure, C28H20Cl4N6O8, CAS 57440-77-4
3-[[1-[4-[[2-[(5-Carboxy-2-chlorophenyl)diazenyl]-3-oxobutanoyl]amino]-2,5-dichloroanilino]-1,3-dioxobutan-2-yl]diazenyl]-4-chlorobenzoic acid
CAS 57440-77-4C28H20Cl4N6O8
N,N'-(1,4-Phenylene)bis{2-[(2-ethoxyphenyl)diazenyl]-3-oxobutanamide} chemical structure, C30H32N6O6, CAS 222173-01-5
N,N'-(1,4-Phenylene)bis{2-[(2-ethoxyphenyl)diazenyl]-3-oxobutanamide}
CAS 222173-01-5C30H32N6O6
Benzoic acid, 2,2'-[1,4-phenylenebis[imino(1-acetyl-2-oxo-2,1-ethanediyl)azo]]bis-, dimethyl ester chemical structure, C30H28N6O8, CAS 79102-67-3
Benzoic acid, 2,2'-[1,4-phenylenebis[imino(1-acetyl-2-oxo-2,1-ethanediyl)azo]]bis-, dimethyl ester
CAS 79102-67-3C30H28N6O8
N,N'-1,4-Phenylenebis((2-(4-chloro-o-tolyl)azo)-3-oxobutyramide) chemical structure, C28H26Cl2N6O4, CAS 40366-31-2
N,N'-1,4-Phenylenebis((2-(4-chloro-o-tolyl)azo)-3-oxobutyramide)
CAS 40366-31-2C28H26Cl2N6O4
Butanamide, N,Na(2)-1,4-phenylenebis[2-[(2-methoxy-4-nitrophenyl)azo]-3-oxo- chemical structure, C28H26N8O10, CAS 83372-55-8
Butanamide, N,Na(2)-1,4-phenylenebis[2-[(2-methoxy-4-nitrophenyl)azo]-3-oxo-
CAS 83372-55-8C28H26N8O10
1,1a(2),4,4a(2)-Tetramethyl 2,2a(2)-[(2-chloro-1,4-phenylene)bis[imino(1-acetyl-2-oxo-2,1-ethanediyl)-2,1-diazenediyl]]bis[1,4-benzenedicarboxylate] chemical structure, C34H31ClN6O12, CAS 156564-67-9
1,1a(2),4,4a(2)-Tetramethyl 2,2a(2)-[(2-chloro-1,4-phenylene)bis[imino(1-acetyl-2-oxo-2,1-ethanediyl)-2,1-diazenediyl]]bis[1,4-benzenedicarboxylate]
CAS 156564-67-9C34H31ClN6O12
3,3a(2)-[(2-Chloro-1,4-phenylene)bis[imino(1-acetyl-2-oxo-2,1-ethanediyl)-2,1-diazenediyl]]bis[4-methylbenzamide] chemical structure, C30H29ClN8O6, CAS 253430-12-5
3,3a(2)-[(2-Chloro-1,4-phenylene)bis[imino(1-acetyl-2-oxo-2,1-ethanediyl)-2,1-diazenediyl]]bis[4-methylbenzamide]
CAS 253430-12-5C30H29ClN8O6