Murcko scaffold
Ring system with 2 rings and 16 atoms
52 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 52
- With full pages
- 6
Scaffold SMILES
O=c1[nH]cc(N=Nc2ccccc2)c(=O)[nH]1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=c1[nH]cc(N=Nc2ccccc2)c(=O)[nH]1](/scaffold/LDDWYPVYAXWKLH-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 52 chemicals
6-Methyl-5-phenylazouracil
CAS 15020-66-3C11H10N4O2
![6-Amino-5-[(2-chlorophenyl)diazenyl]-1,3-dimethylpyrimidine-2,4-dione chemical structure, C12H12ClN5O2, CAS 6336-10-3](/s/WBDCCKNEZYGIHP-UHFFFAOYSA-N.svg)
6-Amino-5-[(2-chlorophenyl)diazenyl]-1,3-dimethylpyrimidine-2,4-dione
CAS 6336-10-3C12H12ClN5O2
![6-Amino-5-[(4-chlorophenyl)diazenyl]-1,3-dimethylpyrimidine-2,4-dione chemical structure, C12H12ClN5O2, CAS 63351-22-4](/s/SBVUPRRBCXGKOU-UHFFFAOYSA-N.svg)
6-Amino-5-[(4-chlorophenyl)diazenyl]-1,3-dimethylpyrimidine-2,4-dione
CAS 63351-22-4C12H12ClN5O2
![5-[2-(4-Nitrophenyl)hydrazinylidene]pyrimidine-2,4,6(1H,3H,5H)-trione chemical structure, C10H7N5O5, CAS 19849-55-9](/s/DCSJHKBIVXVCSE-UHFFFAOYSA-N.svg)
5-[2-(4-Nitrophenyl)hydrazinylidene]pyrimidine-2,4,6(1H,3H,5H)-trione
CAS 19849-55-9C10H7N5O5
5-(2-Phenylhydrazin-1-ylidene)-1,3-diazinane-2,4,6-trione
CAS 19849-58-2C10H8N4O3
![4-[(6-Amino-2,4-dioxo-1H-pyrimidin-5-yl)diazenyl]benzenesulfonamide chemical structure, C10H10N6O4S, CAS 52551-02-7](/s/WFAXTQUMPXIYGS-UHFFFAOYSA-N.svg)
4-[(6-Amino-2,4-dioxo-1H-pyrimidin-5-yl)diazenyl]benzenesulfonamide
CAS 52551-02-7C10H10N6O4S
![5-[(3-Methoxyphenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione chemical structure, C13H14N4O4, CAS 30201-43-5](/s/RTQWTYPXAKGXFM-UHFFFAOYSA-N.svg)
5-[(3-Methoxyphenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione
CAS 30201-43-5C13H14N4O4
![5-[(3,5-Dichlorophenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione chemical structure, C12H10Cl2N4O3, CAS 30201-47-9](/s/JPLJMHVGMUOPLC-UHFFFAOYSA-N.svg)
5-[(3,5-Dichlorophenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione
CAS 30201-47-9C12H10Cl2N4O3
![5-[(2,3-Dichlorophenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione chemical structure, C12H10Cl2N4O3, CAS 30201-45-7](/s/QFTNZFSSJUBSCW-UHFFFAOYSA-N.svg)
5-[(2,3-Dichlorophenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione
CAS 30201-45-7C12H10Cl2N4O3
![1,3-Dimethyl-5-[(2-nitrophenyl)hydrazinylidene]-1,3-diazinane-2,4,6-trione chemical structure, C12H11N5O5, CAS 30201-38-8](/s/MFHVMXSSDUWSAV-UHFFFAOYSA-N.svg)
1,3-Dimethyl-5-[(2-nitrophenyl)hydrazinylidene]-1,3-diazinane-2,4,6-trione
CAS 30201-38-8C12H11N5O5
![5-[(4-Chlorophenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione chemical structure, C12H11ClN4O3, CAS 30201-40-2](/s/CBACZLAQJMVOEC-UHFFFAOYSA-N.svg)
5-[(4-Chlorophenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione
CAS 30201-40-2C12H11ClN4O3
![5-[(2,5-Dichloro-4-nitrophenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione chemical structure, C12H9Cl2N5O5, CAS 30201-53-7](/s/CEQSPVSIQWYLOE-UHFFFAOYSA-N.svg)
5-[(2,5-Dichloro-4-nitrophenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione
CAS 30201-53-7C12H9Cl2N5O5
![1,3-Dimethyl-5-[(3-nitrophenyl)hydrazinylidene]-1,3-diazinane-2,4,6-trione chemical structure, C12H11N5O5, CAS 30201-39-9](/s/XYSLBNCXXVDBHV-UHFFFAOYSA-N.svg)
1,3-Dimethyl-5-[(3-nitrophenyl)hydrazinylidene]-1,3-diazinane-2,4,6-trione
CAS 30201-39-9C12H11N5O5
![1,3-Dimethyl-5-[(2-methylphenyl)hydrazinylidene]-1,3-diazinane-2,4,6-trione chemical structure, C13H14N4O3, CAS 30201-41-3](/s/GPBJRJPGJJYYDW-UHFFFAOYSA-N.svg)
1,3-Dimethyl-5-[(2-methylphenyl)hydrazinylidene]-1,3-diazinane-2,4,6-trione
CAS 30201-41-3C13H14N4O3
![5-[(2,4-Dichlorophenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione chemical structure, C12H10Cl2N4O3, CAS 30201-46-8](/s/NPGKMRZEEZHBEN-UHFFFAOYSA-N.svg)
5-[(2,4-Dichlorophenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione
CAS 30201-46-8C12H10Cl2N4O3
1,3-Dimethyl-5-(phenylhydrazinylidene)-1,3-diazinane-2,4,6-trione
CAS 30189-12-9C12H12N4O3
![5-[(2,6-Dimethylphenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione chemical structure, C14H16N4O3, CAS 30201-51-5](/s/CXGXJXDYJCROGP-UHFFFAOYSA-N.svg)
5-[(2,6-Dimethylphenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione
CAS 30201-51-5C14H16N4O3
![5-[(2,5-Dimethylphenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione chemical structure, C14H16N4O3, CAS 30201-50-4](/s/HPZRVMUAUGAXDE-UHFFFAOYSA-N.svg)
5-[(2,5-Dimethylphenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione
CAS 30201-50-4C14H16N4O3
![5-[(3,4-Dimethylphenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione chemical structure, C14H16N4O3, CAS 30201-52-6](/s/LNTWDRQLCOHXBT-UHFFFAOYSA-N.svg)
5-[(3,4-Dimethylphenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione
CAS 30201-52-6C14H16N4O3
![5-[(4-Methoxyphenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione chemical structure, C13H14N4O4, CAS 30201-44-6](/s/JJZQNLUICSETQJ-UHFFFAOYSA-N.svg)
5-[(4-Methoxyphenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione
CAS 30201-44-6C13H14N4O4
![5-[(2-Ethylphenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione chemical structure, C14H16N4O3, CAS 30201-42-4](/s/SQWNTUBBJUQPIJ-UHFFFAOYSA-N.svg)
5-[(2-Ethylphenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione
CAS 30201-42-4C14H16N4O3
![5-[(4-Chloro-2,5-dimethoxyphenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione chemical structure, C14H15ClN4O5, CAS 30201-54-8](/s/GNQJFQZFGKDVEU-UHFFFAOYSA-N.svg)
5-[(4-Chloro-2,5-dimethoxyphenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione
CAS 30201-54-8C14H15ClN4O5
![5-[(5-Chloro-2,4-dimethoxyphenyl)diazenyl]-6-hydroxy-1,3-dimethylpyrimidine-2,4-dione chemical structure, C14H15ClN4O5, CAS 30201-55-9](/s/QMRLELVETMOIAK-UHFFFAOYSA-N.svg)
5-[(5-Chloro-2,4-dimethoxyphenyl)diazenyl]-6-hydroxy-1,3-dimethylpyrimidine-2,4-dione
CAS 30201-55-9C14H15ClN4O5
![5-[(2,3-Dimethylphenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione chemical structure, C14H16N4O3, CAS 30201-49-1](/s/FWUWTDFPQIJHRB-UHFFFAOYSA-N.svg)
5-[(2,3-Dimethylphenyl)hydrazinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione
CAS 30201-49-1C14H16N4O3
- 6-Pentyl-5-phenyldiazenyl-1H-pyrimidine-2,4-dione15020-68-5C15H18N4O2
- 6-Amino-1-methyl-5-phenyldiazenylpyrimidine-2,4-dione54058-36-5C11H11N5O2
- 5-[2-(4-Chlorophenyl)hydrazinylidene]pyrimidine-2,4,6(1H,3H,5H)-trione7293-30-3C10H7ClN4O3
- 4-[2-(2,4,6-Trioxotetrahydro-5(2H)-pyrimidinylidene)hydrazino]benzoic acid314757-93-2C11H8N4O5
- 3-[2-(2,4,6-Trioxotetrahydro-5(2H)-pyrimidinylidene)hydrazino]benzoic acid314758-28-6C11H8N4O5
- 5-(2-(2,6-Dibromo-4-chlorophenyl)hydrazono)pyrimidine-2,4,6(1H,3H,5H)-trione360567-78-8C10H5Br2ClN4O3
- (E)-5-Bromo-2-(2-(2,6-dihydroxy-4-oxopyrimidin-5(4H)-ylidene)hydrazinyl)benzoic acid847364-95-8C11H7BrN4O5
- 2,4,5,6(1H,3H)-pyrimidinetetrone 5-[(3-bromophenyl)hydrazone]326911-50-6C10H7BrN4O3
- N,N-Diethyl-4-[2-(2,4,6-trioxotetrahydropyrimidin-5(2H)-ylidene)hydrazino]benzenesulfonamide326911-65-3C14H17N5O5S
- 5-(2-(2-Chloro-5-(trifluoromethyl)phenyl)hydrazono)pyrimidine-2,4,6(1H,3H,5H)-trione303793-25-1C11H6ClF3N4O3
- 5-(2-{4-[(Difluoromethyl)sulfanyl]phenyl}hydrazin-1-ylidene)-1,3-diazinane-2,4,6-trione326911-64-2C11H8F2N4O3S
- (E)-N,N-Diethyl-4-(2-(2-hydroxy-4-imino-6-oxo-1,6-dihydropyrimidin-5(4H)-ylidene)hydrazinyl)benzenesulfonamide327088-91-5C14H18N6O4S
- 4-[2-(1,3-Dimethyl-2,4,6-trioxo-1,3-diazinan-5-ylidene)hydrazin-1-yl]-N,N-diethylbenzene-1-sulfonamide326911-82-4C16H21N5O5S
- 5-(2-(4-(Difluoromethoxy)phenyl)hydrazono)pyrimidine-2,4,6(1H,3H,5H)-trione302935-80-4C11H8F2N4O4
- 5-[[(3-Nitrophenyl)amino]imino]barbituric acid19849-54-8C10H7N5O5
- 5-[2-(2-Nitrophenyl)hydrazinylidene]pyrimidine-2,4,6(1H,3H,5H)-trione111709-57-0C10H7N5O5
- 5-[[(4-Methoxyphenyl)amino]imino]barbituric acid19849-56-0C11H10N4O4
- 6-Hydroxy-5-[(2-methylphenyl)diazenyl]-1H-pyrimidine-2,4-dione111709-59-2C11H10N4O3
- 5-[(3-Methoxy-phenyl)-hydrazono]-pyrimidine-2,4,6-trione303797-38-8C11H10N4O4
- 2,4,5,6(1H,3H)-Pyrimidinetetrone, 5-[2-(4-methoxy-2-nitrophenyl)hydrazone]31353-87-4C11H9N5O6
- (E)-5-(2-(2-Chlorophenyl)hydrazono)-2-hydroxy-6-imino-5,6-dihydropyrimidin-4(3H)-one326912-29-2C10H8ClN5O2
- N,N-Diethyl-3-[2-(2,4,6-trioxotetrahydro-5(2H)-pyrimidinylidene)hydrazino]benzenesulfonamide326911-66-4C14H17N5O5S
- 5-[2-(2,4-Difluorophenyl)diazenyl]-2,4,6-pyrimidinetriol339016-27-2C10H6F2N4O3
- (E)-5-(2-(3-Bromophenyl)hydrazono)-2-hydroxy-6-imino-5,6-dihydropyrimidin-4(3H)-one326912-33-8C10H8BrN5O2
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccccc11,973 chemicals
O=S(=O)(Nc1ccccc1)c1ccccc1978 chemicals
c1ccc(COc2ccccc2)cc1829 chemicals
c1ccc(N=Nc2ccccc2)cc1383 chemicals
C(=Nc1ccccc1)c1ccccc1379 chemicals
O=C(Oc1ccccc1)c1ccccc1309 chemicals
c1ccc(CNc2ccccc2)cc1309 chemicals
C(=Cc1ccccc1)c1ccccc1279 chemicals
c1ccc(CCc2ccccc2)cc1264 chemicals
O=C(Nc1ccccc1)c1cccnc1140 chemicals
O=C(Cc1ccccc1)c1ccccc1137 chemicals
O=C(Nc1ccccn1)c1ccccc1120 chemicals