CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 19 atoms

7 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
7
With full pages
4
Scaffold SMILES

O=C(C=Cc1ccccc1)Nc1cc(=O)[nH]c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)Nc1cc(=O)[nH]c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

(E)-N-(1,3-Dimethyl-2,6-dioxopyrimidin-4-yl)-3-(4-methoxyphenyl)prop-2-enamide chemical structure, C16H17N3O4, CAS 1164564-13-9
(E)-N-(1,3-Dimethyl-2,6-dioxopyrimidin-4-yl)-3-(4-methoxyphenyl)prop-2-enamide
CAS 1164564-13-9C16H17N3O4
(E)-N-(1,3-Dimethyl-2,6-dioxopyrimidin-4-yl)-3-phenylprop-2-enamide chemical structure, C15H15N3O3, CAS 1164534-50-2
(E)-N-(1,3-Dimethyl-2,6-dioxopyrimidin-4-yl)-3-phenylprop-2-enamide
CAS 1164534-50-2C15H15N3O3
(2E)-3-(3,4-Dimethoxyphenyl)-N-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)prop-2-enamide chemical structure, C17H19N3O5
(2E)-3-(3,4-Dimethoxyphenyl)-N-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)prop-2-enamide
C17H19N3O5
(Z)-3-(3,4-Dimethoxyphenyl)-N-(1,3-dimethyl-2,6-dioxopyrimidin-4-yl)prop-2-enamide chemical structure, C17H19N3O5, CAS 329043-22-3
(Z)-3-(3,4-Dimethoxyphenyl)-N-(1,3-dimethyl-2,6-dioxopyrimidin-4-yl)prop-2-enamide
CAS 329043-22-3C17H19N3O5
(Z)-N-(1,3-Dimethyl-2,6-dioxopyrimidin-4-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-enamide chemical structure, C18H21N3O6, CAS 633296-62-5
(Z)-N-(1,3-Dimethyl-2,6-dioxopyrimidin-4-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-enamide
CAS 633296-62-5C18H21N3O6
(E)-3-(3,4-Dichlorophenyl)-N-(1,3-dimethyl-2,6-dioxopyrimidin-4-yl)prop-2-enamide chemical structure, C15H13Cl2N3O3, CAS 1164491-07-9
(E)-3-(3,4-Dichlorophenyl)-N-(1,3-dimethyl-2,6-dioxopyrimidin-4-yl)prop-2-enamide
CAS 1164491-07-9C15H13Cl2N3O3
(E)-N-(5-Amino-1,3-diethyl-2,6-dioxopyrimidin-4-yl)-3-(3,4-dimethoxyphenyl)prop-2-enamide chemical structure, C19H24N4O5, CAS 2390200-26-5
(E)-N-(5-Amino-1,3-diethyl-2,6-dioxopyrimidin-4-yl)-3-(3,4-dimethoxyphenyl)prop-2-enamide
CAS 2390200-26-5C19H24N4O5