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Murcko scaffold

Ring system with 3 rings and 14 atoms

25 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
25
With full pages
1
Scaffold SMILES

O=C1C=C2CC3CCCCC3CC2O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=C2CC3CCCCC3CC2O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

Farformolide B chemical structure, C17H26O5, CAS 69618-93-5
Farformolide B
CAS 69618-93-5C17H26O5
Naphtho(2,3-b)furan-2(4H)-one, 4a,5,6,7,8,8a,9,9a-octahydro-9a-hydroxy-3,4a,5-trimethyl-, (4aR,5S,8aR,9aR)- chemical structure, C15H22O3, CAS 73171-25-2
Naphtho(2,3-b)furan-2(4H)-one, 4a,5,6,7,8,8a,9,9a-octahydro-9a-hydroxy-3,4a,5-trimethyl-, (4aR,5S,8aR,9aR)-
CAS 73171-25-2C15H22O3
6beta,8beta-Dihydroxyeremophilenolide chemical structure, C15H22O4, CAS 58848-38-7
6beta,8beta-Dihydroxyeremophilenolide
CAS 58848-38-7C15H22O4
(4aR,5S,8aR,9aS)-4a,5,6,7,8,8a,9,9a-Octahydro-3,4a,5-trimethylnaphtho(2,3-b)furan-2(4H)-one chemical structure, C15H22O2, CAS 4871-90-3
(4aR,5S,8aR,9aS)-4a,5,6,7,8,8a,9,9a-Octahydro-3,4a,5-trimethylnaphtho(2,3-b)furan-2(4H)-one
CAS 4871-90-3C15H22O2
2-Butenoic acid, 2-methyl-, (4aR,5R,6S,8aS,9aS)-2,4,4a,5,6,7,8,8a,9,9a-decahydro-8a-hydroxy-3,4a,5-trimethyl-2-oxonaphtho(2,3-b)furan-6-yl ester, (2Z)- chemical structure, C20H28O5, CAS 69618-92-4
2-Butenoic acid, 2-methyl-, (4aR,5R,6S,8aS,9aS)-2,4,4a,5,6,7,8,8a,9,9a-decahydro-8a-hydroxy-3,4a,5-trimethyl-2-oxonaphtho(2,3-b)furan-6-yl ester, (2Z)-
CAS 69618-92-4C20H28O5
[(4S,4aS,5R,6R,8aR,9aR)-4-Hydroxy-3,4a,5-trimethyl-2-oxo-4,5,6,7,8,8a,9,9a-octahydrobenzo[f][1]benzofuran-6-yl] (Z)-2-methylbut-2-enoate chemical structure, C20H28O5, CAS 73171-27-4
[(4S,4aS,5R,6R,8aR,9aR)-4-Hydroxy-3,4a,5-trimethyl-2-oxo-4,5,6,7,8,8a,9,9a-octahydrobenzo[f][1]benzofuran-6-yl] (Z)-2-methylbut-2-enoate
CAS 73171-27-4C20H28O5
(4S,4aS,5R,6S,8aR,9aR)-6-Hydroxy-4,9a-dimethoxy-3,4a,5-trimethyl-5,6,7,8,8a,9-hexahydro-4H-benzo[f][1]benzofuran-2-one chemical structure, C17H26O5, CAS 162613-65-2
(4S,4aS,5R,6S,8aR,9aR)-6-Hydroxy-4,9a-dimethoxy-3,4a,5-trimethyl-5,6,7,8,8a,9-hexahydro-4H-benzo[f][1]benzofuran-2-one
CAS 162613-65-2C17H26O5
[(4S,4aS,5R,6S,8aR,9aR)-6-Hydroxy-3,4a,5-trimethyl-2-oxo-4,5,6,7,8,8a,9,9a-octahydrobenzo[f][1]benzofuran-4-yl] (E)-2-methylbut-2-enoate chemical structure, C20H28O5, CAS 149475-46-7
[(4S,4aS,5R,6S,8aR,9aR)-6-Hydroxy-3,4a,5-trimethyl-2-oxo-4,5,6,7,8,8a,9,9a-octahydrobenzo[f][1]benzofuran-4-yl] (E)-2-methylbut-2-enoate
CAS 149475-46-7C20H28O5
(4S,4aS,5R,6S,8aR,9aR)-6-Hydroxy-4-methoxy-3,4a,5-trimethyl-4,5,6,7,8,8a,9,9a-octahydrobenzo[f][1]benzofuran-2-one chemical structure, C16H24O4, CAS 162613-64-1
(4S,4aS,5R,6S,8aR,9aR)-6-Hydroxy-4-methoxy-3,4a,5-trimethyl-4,5,6,7,8,8a,9,9a-octahydrobenzo[f][1]benzofuran-2-one
CAS 162613-64-1C16H24O4
[(4S,4aS,5R,6S,8aR,9aR)-3,4a,5-Trimethyl-4-[(Z)-2-methylbut-2-enoyl]oxy-2-oxo-4,5,6,7,8,8a,9,9a-octahydrobenzo[f][1]benzofuran-6-yl] (Z)-2-methylbut-2-enoate chemical structure, C25H34O6, CAS 149475-47-8
[(4S,4aS,5R,6S,8aR,9aR)-3,4a,5-Trimethyl-4-[(Z)-2-methylbut-2-enoyl]oxy-2-oxo-4,5,6,7,8,8a,9,9a-octahydrobenzo[f][1]benzofuran-6-yl] (Z)-2-methylbut-2-enoate
CAS 149475-47-8C25H34O6
[(4S,4aS,5R,6S,8aR,9aR)-6-Hydroxy-3,4a,5-trimethyl-2-oxo-4,5,6,7,8,8a,9,9a-octahydrobenzo[f][1]benzofuran-4-yl] 3-chloro-2-hydroxy-2-methylbutanoate chemical structure, C20H29ClO6, CAS 171422-90-5
[(4S,4aS,5R,6S,8aR,9aR)-6-Hydroxy-3,4a,5-trimethyl-2-oxo-4,5,6,7,8,8a,9,9a-octahydrobenzo[f][1]benzofuran-4-yl] 3-chloro-2-hydroxy-2-methylbutanoate
CAS 171422-90-5C20H29ClO6
[(4S,4aR,5R,6S,8aS,9R,9aR)-6,9,9a-Trihydroxy-3,4a,5-trimethyl-2-oxo-5,6,7,8,8a,9-hexahydro-4H-benzo[f][1]benzofuran-4-yl] (Z)-2-methylbut-2-enoate chemical structure, C20H28O7, CAS 171422-89-2
[(4S,4aR,5R,6S,8aS,9R,9aR)-6,9,9a-Trihydroxy-3,4a,5-trimethyl-2-oxo-5,6,7,8,8a,9-hexahydro-4H-benzo[f][1]benzofuran-4-yl] (Z)-2-methylbut-2-enoate
CAS 171422-89-2C20H28O7
(4aR,5S,8aS,9aS)-4a,5,6,7,8,8a,9,9a-Octahydro-8a,9a-dihydroxy-3,4a,5-trimethylnaphtho(2,3-b)furan-2(4H)-one chemical structure, C15H22O4, CAS 130430-98-7
(4aR,5S,8aS,9aS)-4a,5,6,7,8,8a,9,9a-Octahydro-8a,9a-dihydroxy-3,4a,5-trimethylnaphtho(2,3-b)furan-2(4H)-one
CAS 130430-98-7C15H22O4
[(4S,4aR,5R,6S,8aS,9S,9aS)-6,9-Dihydroxy-3,4a,5-trimethyl-2-oxo-4,5,6,7,8,8a,9,9a-octahydrobenzo[f][1]benzofuran-4-yl] (Z)-2-methylbut-2-enoate chemical structure, C20H28O6, CAS 171422-88-1
[(4S,4aR,5R,6S,8aS,9S,9aS)-6,9-Dihydroxy-3,4a,5-trimethyl-2-oxo-4,5,6,7,8,8a,9,9a-octahydrobenzo[f][1]benzofuran-4-yl] (Z)-2-methylbut-2-enoate
CAS 171422-88-1C20H28O6
(4S,4aS,5R,6S,8aR,9aR)-2,4,4a,5,6,7,8,8a,9,9a-Decahydro-3,4a,5-trimethyl-6-[[(2E)-3-[(R)-methylsulfinyl]-1-oxo-2-propen-1-yl]oxy]-2-oxonaphtho[2,3-b]furan-4-yl (2Z)-2-methyl-2-butenoate chemical structure, C24H32O7S, CAS 182127-79-3
(4S,4aS,5R,6S,8aR,9aR)-2,4,4a,5,6,7,8,8a,9,9a-Decahydro-3,4a,5-trimethyl-6-[[(2E)-3-[(R)-methylsulfinyl]-1-oxo-2-propen-1-yl]oxy]-2-oxonaphtho[2,3-b]furan-4-yl (2Z)-2-methyl-2-butenoate
CAS 182127-79-3C24H32O7S
6beta-Hydroxyeremophilenolide chemical structure, C15H22O3, CAS 10250-03-0
6beta-Hydroxyeremophilenolide
CAS 10250-03-0C15H22O3
2-Butenoic acid, 2-methyl-, (4S,4aS,5R,6S,8aR,9aR)-2,4,4a,5,6,7,8,8a,9,9a-decahydro-6,9a-dihydroxy-3,4a,5-trimethyl-2-oxonaphtho[2,3-b]furan-4-yl ester, (2E)- chemical structure, C20H28O6, CAS 162613-66-3
2-Butenoic acid, 2-methyl-, (4S,4aS,5R,6S,8aR,9aR)-2,4,4a,5,6,7,8,8a,9,9a-decahydro-6,9a-dihydroxy-3,4a,5-trimethyl-2-oxonaphtho[2,3-b]furan-4-yl ester, (2E)-
CAS 162613-66-3C20H28O6
2-Butenoic acid, 2-methyl-, (4S,4aS,5R,6S,8aR,9aS)-2,4,4a,5,6,7,8,8a,9,9a-decahydro-6,9a-dihydroxy-3,4a,5-trimethyl-2-oxonaphtho[2,3-b]furan-4-yl ester, (2E)- chemical structure, C20H28O6, CAS 162613-67-4
2-Butenoic acid, 2-methyl-, (4S,4aS,5R,6S,8aR,9aS)-2,4,4a,5,6,7,8,8a,9,9a-decahydro-6,9a-dihydroxy-3,4a,5-trimethyl-2-oxonaphtho[2,3-b]furan-4-yl ester, (2E)-
CAS 162613-67-4C20H28O6
Mairetolide F chemical structure, C15H22O4, CAS 915403-89-3
Mairetolide F
CAS 915403-89-3C15H22O4
4alpha,8beta-Dihydroxy-3alpha-(2-hydroxy-3-acetoxy-2-methylbutyryloxy)eudesm-7(11)-en-12,8alpha-olide chemical structure, C22H32O9, CAS 1442989-33-4
4alpha,8beta-Dihydroxy-3alpha-(2-hydroxy-3-acetoxy-2-methylbutyryloxy)eudesm-7(11)-en-12,8alpha-olide
CAS 1442989-33-4C22H32O9
4,8-Dihydroxyeudesm-7(11)-en-12,8-olide chemical structure, C15H22O4, CAS 1231208-53-9
4,8-Dihydroxyeudesm-7(11)-en-12,8-olide
CAS 1231208-53-9C15H22O4
(4S,4aR,5S,8aR,9aS)-4a,5,6,7,8,8a,9,9a-Octahydro-4-hydroxy-9a-methoxy-3,4a,5-trimethylnaphtho(2,3-b)furan-2(4H)-one chemical structure, C16H24O4, CAS 58848-45-6
(4S,4aR,5S,8aR,9aS)-4a,5,6,7,8,8a,9,9a-Octahydro-4-hydroxy-9a-methoxy-3,4a,5-trimethylnaphtho(2,3-b)furan-2(4H)-one
CAS 58848-45-6C16H24O4
(4S,4aS,5R,6S,8aR,9aS)-2,4,4a,5,6,7,8,8a,9,9a-Decahydro-6-hydroxy-3,4a,5-trimethyl-2-oxonaphtho[2,3-b]furan-4-yl (2Z)-2-methyl-2-butenoate chemical structure, C20H28O5, CAS 199675-13-3
(4S,4aS,5R,6S,8aR,9aS)-2,4,4a,5,6,7,8,8a,9,9a-Decahydro-6-hydroxy-3,4a,5-trimethyl-2-oxonaphtho[2,3-b]furan-4-yl (2Z)-2-methyl-2-butenoate
CAS 199675-13-3C20H28O5
(4S,4aS,5R,6S,8aR,9aS)-2,4,4a,5,6,7,8,8a,9,9a-Decahydro-6,9a-dihydroxy-3,4a,5-trimethyl-2-oxonaphtho[2,3-b]furan-4-yl 3-chloro-2-hydroxy-2-methylbutanoate chemical structure, C20H29ClO7, CAS 264607-21-8
(4S,4aS,5R,6S,8aR,9aS)-2,4,4a,5,6,7,8,8a,9,9a-Decahydro-6,9a-dihydroxy-3,4a,5-trimethyl-2-oxonaphtho[2,3-b]furan-4-yl 3-chloro-2-hydroxy-2-methylbutanoate
CAS 264607-21-8C20H29ClO7