Murcko scaffold
Bicyclo(3.2.1)octane scaffold
268 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 8
- Chemicals
- 268
- With full pages
- 25
Scaffold SMILES
C1CC2CCC(C1)C2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 268 chemicals
Bicyclo(3.2.1)octan-2-ol
CAS 5602-48-2C8H14O
![1,5-Dimethylbicyclo[3.2.1]octan-8-ol chemical structure, C10H18O, CAS 60329-20-6](/s/VLRZZNSBIMFXGK-UHFFFAOYSA-N.svg)
1,5-Dimethylbicyclo[3.2.1]octan-8-ol
CAS 60329-20-6C10H18O
2-Aminobicyclo(3.2.1)octane-2-carboxylic acid
CAS 55011-70-6C9H15NO2
![1,5,8-Trimethylbicyclo[3.2.1]octan-8-ol chemical structure, C11H20O, CAS 84681-91-4](/s/MBWDTSVSVTZUBE-UHFFFAOYSA-N.svg)
1,5,8-Trimethylbicyclo[3.2.1]octan-8-ol
CAS 84681-91-4C11H20O
![Bicyclo[3.2.1]octan-8-ol, 8-ethyl-1,5-dimethyl- chemical structure, C12H22O, CAS 84681-92-5](/s/AKVDDUFUTRWZKY-UHFFFAOYSA-N.svg)
Bicyclo[3.2.1]octan-8-ol, 8-ethyl-1,5-dimethyl-
CAS 84681-92-5C12H22O
![Bicyclo[3.2.1]octan-8-ol, 1,5-dimethyl-, 8-acetate chemical structure, C12H20O2, CAS 75911-79-4](/s/PWMCEJOFYWFVPA-UHFFFAOYSA-N.svg)
Bicyclo[3.2.1]octan-8-ol, 1,5-dimethyl-, 8-acetate
CAS 75911-79-4C12H20O2
![2-Cyanobicyclo[3.2.1]oct-2-yl acetate chemical structure, C11H15NO2, CAS 1202-82-0](/s/WJESTEMTEBGBEU-UHFFFAOYSA-N.svg)
2-Cyanobicyclo[3.2.1]oct-2-yl acetate
CAS 1202-82-0C11H15NO2
Bicyclo(3.2.1)octane
CAS 6221-55-2C8H14
2-Methylbicyclo(3.2.1)octan-2-ol
CAS 5019-84-1C9H16O
![Bicyclo[3.2.1]octan-8-amine chemical structure, C8H15N, CAS 740738-40-3](/s/UPSSJABEWAOMQR-UHFFFAOYSA-N.svg)
Bicyclo[3.2.1]octan-8-amine
CAS 740738-40-3C8H15N
Bicyclo(3.2.1)octane, 1-methyl-
CAS 3673-75-4C9H16
![Bicyclo[3.2.1]octan-6-ol chemical structure, C8H14O, CAS 23392-00-9](/s/HNCXRKBVFWLKTR-UHFFFAOYSA-N.svg)
Bicyclo[3.2.1]octan-6-ol
CAS 23392-00-9C8H14O
![Bicyclo[3.2.1]octane-2,2-diol chemical structure, C8H14O2, CAS 253875-88-6](/s/XARWQKZGAISNQF-UHFFFAOYSA-N.svg)
Bicyclo[3.2.1]octane-2,2-diol
CAS 253875-88-6C8H14O2
![Bicyclo[3.2.1]octan-1-ol chemical structure, C8H14O, CAS 134654-98-1](/s/YOUYXVQUIJGXKB-UHFFFAOYSA-N.svg)
Bicyclo[3.2.1]octan-1-ol
CAS 134654-98-1C8H14O
![2-Hydroxybicyclo[3.2.1]octane-6-carboxylic acid chemical structure, C9H14O3, CAS 257932-29-9](/s/FSQSHXLJRFYYMV-UHFFFAOYSA-N.svg)
2-Hydroxybicyclo[3.2.1]octane-6-carboxylic acid
CAS 257932-29-9C9H14O3
Bicyclo(3.2.1)octane-3-carboxamide, 3-methyl-
CAS 95685-42-0C10H17NO
![(1S,2S,5S)-Bicyclo[3.2.1]octan-2-ol chemical structure, C8H14O, CAS 61277-91-6](/s/PVDVHTXERCKKSW-FXQIFTODSA-N.svg)
(1S,2S,5S)-Bicyclo[3.2.1]octan-2-ol
CAS 61277-91-6C8H14O
![Bicyclo[3.2.1]octan-3-ol chemical structure, C8H14O, CAS 29804-62-4](/s/HREZEXWGSYQUAI-UHFFFAOYSA-N.svg)
Bicyclo[3.2.1]octan-3-ol
CAS 29804-62-4C8H14O
![Exo-bicyclo[3.2.1]octan-3-ol chemical structure, C8H14O, CAS 13387-09-2](/s/HREZEXWGSYQUAI-DHBOJHSNSA-N.svg)
Exo-bicyclo[3.2.1]octan-3-ol
CAS 13387-09-2C8H14O
![Bicyclo[3.2.1]octan-8-ol chemical structure, C8H14O, CAS 29279-58-1](/s/UCLQWJHRXKTKKP-UHFFFAOYSA-N.svg)
Bicyclo[3.2.1]octan-8-ol
CAS 29279-58-1C8H14O
![Bicyclo[3.2.1]octane-1-carboxylic acid chemical structure, C9H14O2, CAS 2534-83-0](/s/HJDYARCZSGKTIG-UHFFFAOYSA-N.svg)
Bicyclo[3.2.1]octane-1-carboxylic acid
CAS 2534-83-0C9H14O2
![rac-[(1R,5S,6R)-5-Aminobicyclo[3.2.1]octan-6-yl]methanol chemical structure, C9H17NO, CAS 104201-30-1](/s/DFYJWLCPYOGFIY-VGMNWLOBSA-N.svg)
rac-[(1R,5S,6R)-5-Aminobicyclo[3.2.1]octan-6-yl]methanol
CAS 104201-30-1C9H17NO
![6-Bicyclo[3.2.1]octanylmethanol chemical structure, C9H16O, CAS 1784642-52-9](/s/RKRSPOQMWINIJR-UHFFFAOYSA-N.svg)
6-Bicyclo[3.2.1]octanylmethanol
CAS 1784642-52-9C9H16O
![Bicyclo[3.2.1]octan-2-amine chemical structure, C8H15N, CAS 30321-42-7](/s/CQQJFQJSVKSJTC-UHFFFAOYSA-N.svg)
Bicyclo[3.2.1]octan-2-amine
CAS 30321-42-7C8H15N
- Rac-(1r,2r,5r)-bicyclo[3.2.1]octan-2-amine704204-47-7C8H15N
- Bicyclo[3.2.1]octan-3-amine736867-32-6C8H15N
- Bicyclo(3.2.1)octane-3-carboxylic acid6221-65-4C9H14O2
- Bicyclo(3.2.1)octane-3-carboxylic acid, methyl ester95685-35-1C10H16O2
- 3-Methylbicyclo[3.2.1]octane-3-carboxylic acid95685-33-9C10H16O2
- Bicyclo(3.2.1)octane-3-carboxylic acid, 3-ethyl-95685-38-4C11H18O2
- Bicyclo(3.2.1)octane-3-carboxylic acid, 3-(1-methylethyl)-95685-40-8C12H20O2
- Bicyclo(3.2.1)octane-3-carboxamide, 3-ethyl-95685-44-2C11H19NO
- Bicyclo(3.2.l)octane-3-carboxamide, 3-(1-methylethyl)-95685-45-3C12H21NO
- Bicyclo(3.2.1)octane-3-carboxamide, N,3-dimethyl-95685-46-4C11H19NO
- Bicyclo[3.2.1]octane-1-carbaldehyde26845-35-2C9H14O
- Dimethyl bicyclo[3.2.1]octane-1,5-dicarboxylate106004-11-9C12H18O4
- Syn-1,5-dimethylbicyclo[3.2.1]oct-8-yl formate72903-06-1C11H18O2
- 5-(Methoxycarbonyl)bicyclo[3.2.1]octane-1-carboxylic acid110371-27-2C11H16O4
- Methyl bicyclo[3.2.1]octane-1-carboxylate81523-46-8C10H16O2
- Bicyclo[3.2.1]octan-1-ylmethanol121455-32-1C9H16O
- Bicyclo[3.2.1]octane-1-carbonyl chloride58541-35-8C9H13ClO
- Bicyclo[3.2.1]octan-6-amine61888-93-5C8H15N
- Bicyclo[3.2.1]octan-6-amine, exo-(9CI)124127-90-8C8H15N
- rac-(1R,5S,6R)-Bicyclo[3.2.1]octan-6-amine124127-92-0C8H15N
- 1-Iodobicyclo[3.2.1]octane61192-26-5C8H13I
- rac-(1R,5S,6S)-Bicyclo[3.2.1]octan-6-ol64170-86-1C8H14O
- rac-(1R,2R,5R)-Bicyclo(3.2.1)octan-2-ol1965-38-4C8H14O
- 1-[(1,5-Dimethylbicyclo[3.2.1]octan-8-yl)oxy]pentan-2-ol143072-16-6C15H28O2
Related scaffolds
Same ring framework with different atoms or bond orders
C1CC2CCC(C1)N289 chemicals
C1CC2CNCC1C243 chemicals
O=C1CC2CCC(C1)N219 chemicals
C1CC2CNC(C1)C219 chemicals
C1NCC2CC1CO217 chemicals
C1CC2COC(C1)O214 chemicals
C1CC2CNCC1N213 chemicals
C1CC2COC(C1)C211 chemicals
C1CC2CCC(C1)O210 chemicals
C1=CC2CCC(C1)N29 chemicals
C1CC2CC(CN2)O18 chemicals
C1CC2CNCC1O26 chemicals