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Murcko scaffold

Ring system with 3 rings and 22 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
15
With full pages
5
Scaffold SMILES

O=C(CSc1ccc(-c2ccccc2)nn1)Nc1nncs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1ccc(-c2ccccc2)nn1)Nc1nncs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-((6-phenylpyridazin-3-yl)thio)acetamide chemical structure, C16H15N5OS2, CAS 872688-40-9
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-((6-phenylpyridazin-3-yl)thio)acetamide
CAS 872688-40-9C16H15N5OS2
2-[6-(4-Chlorophenyl)pyridazin-3-yl]sulfanyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C15H12ClN5OS2, CAS 896052-81-6
2-[6-(4-Chlorophenyl)pyridazin-3-yl]sulfanyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 896052-81-6C15H12ClN5OS2
2-[6-(4-Chlorophenyl)pyridazin-3-yl]sulfanyl-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C16H14ClN5OS2, CAS 896052-85-0
2-[6-(4-Chlorophenyl)pyridazin-3-yl]sulfanyl-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 896052-85-0C16H14ClN5OS2
2-((6-(3,4-Dimethoxyphenyl)pyridazin-3-yl)thio)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C18H19N5O3S2, CAS 893993-49-2
2-((6-(3,4-Dimethoxyphenyl)pyridazin-3-yl)thio)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 893993-49-2C18H19N5O3S2
2-[6-(4-Ethoxyphenyl)pyridazin-3-yl]sulfanyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C17H17N5O2S2, CAS 896054-37-8
2-[6-(4-Ethoxyphenyl)pyridazin-3-yl]sulfanyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 896054-37-8C17H17N5O2S2
2-[6-(4-Ethoxyphenyl)pyridazin-3-yl]sulfanyl-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C18H19N5O2S2, CAS 872689-22-0
2-[6-(4-Ethoxyphenyl)pyridazin-3-yl]sulfanyl-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 872689-22-0C18H19N5O2S2
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-[6-(4-methylphenyl)pyridazin-3-yl]sulfanylacetamide chemical structure, C17H17N5OS2, CAS 872689-38-8
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-[6-(4-methylphenyl)pyridazin-3-yl]sulfanylacetamide
CAS 872689-38-8C17H17N5OS2
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-[6-(2-methoxyphenyl)pyridazin-3-yl]sulfanylacetamide chemical structure, C17H17N5O2S2, CAS 896044-86-3
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-[6-(2-methoxyphenyl)pyridazin-3-yl]sulfanylacetamide
CAS 896044-86-3C17H17N5O2S2
2-[6-(4-Ethylphenyl)pyridazin-3-yl]sulfanyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C17H17N5OS2, CAS 890952-44-0
2-[6-(4-Ethylphenyl)pyridazin-3-yl]sulfanyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 890952-44-0C17H17N5OS2
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-[6-(4-fluorophenyl)pyridazin-3-yl]sulfanylacetamide chemical structure, C16H14FN5OS2, CAS 872695-13-1
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-[6-(4-fluorophenyl)pyridazin-3-yl]sulfanylacetamide
CAS 872695-13-1C16H14FN5OS2
N-(5-Methyl-1,3,4-thiadiazol-2-yl)-2-((6-phenylpyridazin-3-yl)thio)acetamide chemical structure, C15H13N5OS2, CAS 893990-39-1
N-(5-Methyl-1,3,4-thiadiazol-2-yl)-2-((6-phenylpyridazin-3-yl)thio)acetamide
CAS 893990-39-1C15H13N5OS2
N-(5-Methyl-1,3,4-thiadiazol-2-yl)-2-{[6-(2,4,5-trimethylphenyl)pyridazin-3-yl]sulfanyl}acetamide chemical structure, C18H19N5OS2, CAS 923084-15-5
N-(5-Methyl-1,3,4-thiadiazol-2-yl)-2-{[6-(2,4,5-trimethylphenyl)pyridazin-3-yl]sulfanyl}acetamide
CAS 923084-15-5C18H19N5OS2
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-{[6-(2,4,5-trimethylphenyl)pyridazin-3-yl]sulfanyl}acetamide chemical structure, C19H21N5OS2, CAS 922888-20-8
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-{[6-(2,4,5-trimethylphenyl)pyridazin-3-yl]sulfanyl}acetamide
CAS 922888-20-8C19H21N5OS2
2-((6-(4-Bromophenyl)pyridazin-3-yl)thio)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C15H12BrN5OS2, CAS 921056-69-1
2-((6-(4-Bromophenyl)pyridazin-3-yl)thio)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 921056-69-1C15H12BrN5OS2
2-((6-(4-Bromophenyl)pyridazin-3-yl)thio)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C16H14BrN5OS2, CAS 920435-63-8
2-((6-(4-Bromophenyl)pyridazin-3-yl)thio)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 920435-63-8C16H14BrN5OS2