CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 22 atoms

24 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
24
With full pages
4
Scaffold SMILES

O=C(CSc1ccc(-c2ccccc2)nn1)Nc1nccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1ccc(-c2ccccc2)nn1)Nc1nccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

2-((6-(4-Fluorophenyl)pyridazin-3-yl)thio)-N-(thiazol-2-yl)acetamide chemical structure, C15H11FN4OS2, CAS 626223-49-2
2-((6-(4-Fluorophenyl)pyridazin-3-yl)thio)-N-(thiazol-2-yl)acetamide
CAS 626223-49-2C15H11FN4OS2
2-((6-(2-Methoxyphenyl)pyridazin-3-yl)thio)-N-(thiazol-2-yl)acetamide chemical structure, C16H14N4O2S2, CAS 893980-82-0
2-((6-(2-Methoxyphenyl)pyridazin-3-yl)thio)-N-(thiazol-2-yl)acetamide
CAS 893980-82-0C16H14N4O2S2
N-(4-Methyl-1,3-thiazol-2-yl)-2-[(6-phenylpyridazin-3-yl)sulfanyl]acetamide chemical structure, C16H14N4OS2, CAS 893990-34-6
N-(4-Methyl-1,3-thiazol-2-yl)-2-[(6-phenylpyridazin-3-yl)sulfanyl]acetamide
CAS 893990-34-6C16H14N4OS2
2-((6-(4-Chlorophenyl)pyridazin-3-yl)thio)-N-(4-methylthiazol-2-yl)acetamide chemical structure, C16H13ClN4OS2, CAS 893991-50-9
2-((6-(4-Chlorophenyl)pyridazin-3-yl)thio)-N-(4-methylthiazol-2-yl)acetamide
CAS 893991-50-9C16H13ClN4OS2
2-{[6-(4-Ethoxyphenyl)pyridazin-3-yl]sulfanyl}-N-(4-methyl-1,3-thiazol-2-yl)acetamide chemical structure, C18H18N4O2S2, CAS 893974-39-5
2-{[6-(4-Ethoxyphenyl)pyridazin-3-yl]sulfanyl}-N-(4-methyl-1,3-thiazol-2-yl)acetamide
CAS 893974-39-5C18H18N4O2S2
2-[6-(3,4-Dimethoxyphenyl)pyridazin-3-yl]sulfanyl-N-(1,3-thiazol-2-yl)acetamide chemical structure, C17H16N4O3S2, CAS 893993-30-1
2-[6-(3,4-Dimethoxyphenyl)pyridazin-3-yl]sulfanyl-N-(1,3-thiazol-2-yl)acetamide
CAS 893993-30-1C17H16N4O3S2
N-(Thiazol-2-yl)-2-((6-(p-tolyl)pyridazin-3-yl)thio)acetamide chemical structure, C16H14N4OS2, CAS 893976-91-5
N-(Thiazol-2-yl)-2-((6-(p-tolyl)pyridazin-3-yl)thio)acetamide
CAS 893976-91-5C16H14N4OS2
2-((6-(2-Methoxyphenyl)pyridazin-3-yl)thio)-N-(4-methylthiazol-2-yl)acetamide chemical structure, C17H16N4O2S2, CAS 893980-89-7
2-((6-(2-Methoxyphenyl)pyridazin-3-yl)thio)-N-(4-methylthiazol-2-yl)acetamide
CAS 893980-89-7C17H16N4O2S2
2-((6-(4-Ethylphenyl)pyridazin-3-yl)thio)-N-(4-methylthiazol-2-yl)acetamide chemical structure, C18H18N4OS2, CAS 893982-89-3
2-((6-(4-Ethylphenyl)pyridazin-3-yl)thio)-N-(4-methylthiazol-2-yl)acetamide
CAS 893982-89-3C18H18N4OS2
2-[6-(4-Fluorophenyl)pyridazin-3-yl]sulfanyl-N-(4-methyl-1,3-thiazol-2-yl)acetamide chemical structure, C16H13FN4OS2, CAS 893985-58-5
2-[6-(4-Fluorophenyl)pyridazin-3-yl]sulfanyl-N-(4-methyl-1,3-thiazol-2-yl)acetamide
CAS 893985-58-5C16H13FN4OS2
2-((6-(3-Methoxyphenyl)pyridazin-3-yl)thio)-N-(4-methylthiazol-2-yl)acetamide chemical structure, C17H16N4O2S2, CAS 893989-27-0
2-((6-(3-Methoxyphenyl)pyridazin-3-yl)thio)-N-(4-methylthiazol-2-yl)acetamide
CAS 893989-27-0C17H16N4O2S2
2-((6-(3,4-Dimethylphenyl)pyridazin-3-yl)thio)-N-(4-methylthiazol-2-yl)acetamide chemical structure, C18H18N4OS2, CAS 941931-17-5
2-((6-(3,4-Dimethylphenyl)pyridazin-3-yl)thio)-N-(4-methylthiazol-2-yl)acetamide
CAS 941931-17-5C18H18N4OS2
2-((6-(2,4-Dimethylphenyl)pyridazin-3-yl)thio)-N-(thiazol-2-yl)acetamide chemical structure, C17H16N4OS2, CAS 923100-93-0
2-((6-(2,4-Dimethylphenyl)pyridazin-3-yl)thio)-N-(thiazol-2-yl)acetamide
CAS 923100-93-0C17H16N4OS2
2-((6-(2,4-Dimethylphenyl)pyridazin-3-yl)thio)-N-(4-methylthiazol-2-yl)acetamide chemical structure, C18H18N4OS2, CAS 941883-92-7
2-((6-(2,4-Dimethylphenyl)pyridazin-3-yl)thio)-N-(4-methylthiazol-2-yl)acetamide
CAS 941883-92-7C18H18N4OS2
2-((6-(2,5-Dimethoxyphenyl)pyridazin-3-yl)thio)-N-(thiazol-2-yl)acetamide chemical structure, C17H16N4O3S2, CAS 899740-51-3
2-((6-(2,5-Dimethoxyphenyl)pyridazin-3-yl)thio)-N-(thiazol-2-yl)acetamide
CAS 899740-51-3C17H16N4O3S2
N-(Thiazol-2-yl)-2-((6-(o-tolyl)pyridazin-3-yl)thio)acetamide chemical structure, C16H14N4OS2, CAS 923083-22-1
N-(Thiazol-2-yl)-2-((6-(o-tolyl)pyridazin-3-yl)thio)acetamide
CAS 923083-22-1C16H14N4OS2
N-(4-Methylthiazol-2-yl)-2-((6-(o-tolyl)pyridazin-3-yl)thio)acetamide chemical structure, C17H16N4OS2, CAS 922886-97-3
N-(4-Methylthiazol-2-yl)-2-((6-(o-tolyl)pyridazin-3-yl)thio)acetamide
CAS 922886-97-3C17H16N4OS2
2-((6-(2,5-Dimethylphenyl)pyridazin-3-yl)thio)-N-(thiazol-2-yl)acetamide chemical structure, C17H16N4OS2, CAS 922906-68-1
2-((6-(2,5-Dimethylphenyl)pyridazin-3-yl)thio)-N-(thiazol-2-yl)acetamide
CAS 922906-68-1C17H16N4OS2
2-((6-(2,5-Dimethylphenyl)pyridazin-3-yl)thio)-N-(4-methylthiazol-2-yl)acetamide chemical structure, C18H18N4OS2, CAS 941992-32-1
2-((6-(2,5-Dimethylphenyl)pyridazin-3-yl)thio)-N-(4-methylthiazol-2-yl)acetamide
CAS 941992-32-1C18H18N4OS2
N-(4-Methylthiazol-2-yl)-2-((6-(2,4,5-trimethylphenyl)pyridazin-3-yl)thio)acetamide chemical structure, C19H20N4OS2, CAS 941973-84-8
N-(4-Methylthiazol-2-yl)-2-((6-(2,4,5-trimethylphenyl)pyridazin-3-yl)thio)acetamide
CAS 941973-84-8C19H20N4OS2
2-((6-(4-Bromophenyl)pyridazin-3-yl)thio)-N-(4-methylthiazol-2-yl)acetamide chemical structure, C16H13BrN4OS2, CAS 893983-74-9
2-((6-(4-Bromophenyl)pyridazin-3-yl)thio)-N-(4-methylthiazol-2-yl)acetamide
CAS 893983-74-9C16H13BrN4OS2
N-(Thiazol-2-yl)-2-((6-(3,4,5-trimethoxyphenyl)pyridazin-3-yl)thio)acetamide chemical structure, C18H18N4O4S2, CAS 899740-61-5
N-(Thiazol-2-yl)-2-((6-(3,4,5-trimethoxyphenyl)pyridazin-3-yl)thio)acetamide
CAS 899740-61-5C18H18N4O4S2
N-Methyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide chemical structure, C17H16N4OS2, CAS 1135304-61-8
N-Methyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide
CAS 1135304-61-8C17H16N4OS2
N-Methyl-N-(4-methyl-1,3-thiazol-2-yl)-2-[(6-phenylpyridazin-3-yl)sulfanyl]butanamide chemical structure, C19H20N4OS2, CAS 1391736-91-6
N-Methyl-N-(4-methyl-1,3-thiazol-2-yl)-2-[(6-phenylpyridazin-3-yl)sulfanyl]butanamide
CAS 1391736-91-6C19H20N4OS2