Murcko scaffold
4-Benzhydrylpiperidine scaffold
42 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 19
- Chemicals
- 42
- With full pages
- 5
Scaffold SMILES
c1ccc(C(c2ccccc2)C2CCNCC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 42 of 42 chemicals
Ketone, bromomethyl 4-(diphenylhydroxymethyl)piperidino
CAS 143-84-0C20H22BrNO2
Ketone, 4-(diphenylhydroxymethyl)piperidino iodomethyl
CAS 143-86-2C20H22INO2
4-Piperidinemethanol, alpha,alpha-diphenyl-, hydrochloride (1:1)
CAS 1798-50-1C18H22ClNO
Azacyclonol
CAS 115-46-8C18H21NO
Fenoctimine sulfate
CAS 69365-66-8C54H82N4O9S2
Fenoctimine
CAS 69365-65-7C27H38N2
4-Benzhydrylpiperidine
CAS 19841-73-7C18H21N
Mcn 4308
CAS 66619-75-8C22H25NO4
1-Methyl-alpha,alpha-diphenyl-4-piperidinemethanol
CAS 6071-92-7C19H23NO
Piperidine, 1-(2,2-dimethyl-1-oxopropyl)-4-(diphenylmethyl)-
CAS 37015-89-7C23H29NO
Piperidine, 1-(2,2-dimethylpropyl)-4-(diphenylmethyl)-, hydrochloride
CAS 37015-90-0C23H32ClN
(4-Chlorophenyl)-(1-methylpiperidin-4-yl)phenylmethanol
CAS 6317-34-6C19H22ClNO
![Piperidine, 1-[[(1,1-dimethylethyl)imino]methyl]-4-(diphenylmethyl)- chemical structure, C23H30N2, CAS 89656-22-4](/s/YPQCXKVDLZKFSM-UHFFFAOYSA-N.svg)
Piperidine, 1-[[(1,1-dimethylethyl)imino]methyl]-4-(diphenylmethyl)-
CAS 89656-22-4C23H30N2
![N-Ethyl-4-[hydroxy(diphenyl)methyl]piperidine-1-carbothioamide chemical structure, C21H26N2OS, CAS 115020-69-4](/s/UXNIRSLJTHESJA-UHFFFAOYSA-N.svg)
N-Ethyl-4-[hydroxy(diphenyl)methyl]piperidine-1-carbothioamide
CAS 115020-69-4C21H26N2OS
1-(4-Benzhydrylpiperidino)-3-chloro-2,2-dimethylpropan-1-one
CAS 244006-50-6C23H28ClNO
![4-[Bis(4-ethoxyphenyl)methyl]piperidine chemical structure, C22H29NO2, CAS 879620-07-2](/s/SLBWETXQSUZRES-UHFFFAOYSA-N.svg)
4-[Bis(4-ethoxyphenyl)methyl]piperidine
CAS 879620-07-2C22H29NO2
4-(Diphenylimino)-1-(octylimino)methylpiperidine
CAS 84132-11-6C31H42N2O4
Fenoctimine sulfate anhydrous
CAS 69365-67-9C27H40N2O4S
![1,1-Dimethylethyl 4-[[4-[(diethylamino)carbonyl]phenyl](4-fluorophenyl)hydroxymethyl]-1-piperidinecarboxylate chemical structure, C28H37FN2O4, CAS 209808-07-1](/s/BWOAFPWQUNFGCK-UHFFFAOYSA-N.svg)
1,1-Dimethylethyl 4-[[4-[(diethylamino)carbonyl]phenyl](4-fluorophenyl)hydroxymethyl]-1-piperidinecarboxylate
CAS 209808-07-1C28H37FN2O4
![4-[(4-Chlorophenyl)[4-[(diethylamino)carbonyl]phenyl]hydroxymethyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester chemical structure, C28H37ClN2O4, CAS 209808-08-2](/s/GZFUYIIYBUSAGW-UHFFFAOYSA-N.svg)
4-[(4-Chlorophenyl)[4-[(diethylamino)carbonyl]phenyl]hydroxymethyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
CAS 209808-08-2C28H37ClN2O4
1-Piperidinebutanal, 4-(hydroxydiphenylmethyl)-
CAS 105955-84-8C22H27NO2
![4-[(4-Diethylcarbamoyl-phenyl)-hydroxy-phenyl-methyl]-piperidine-1-carboxylic acid tert-butyl ester chemical structure, C28H38N2O4, CAS 193217-40-2](/s/YELLIWMQBAJVBR-UHFFFAOYSA-N.svg)
4-[(4-Diethylcarbamoyl-phenyl)-hydroxy-phenyl-methyl]-piperidine-1-carboxylic acid tert-butyl ester
CAS 193217-40-2C28H38N2O4
![4-[[4-[(Diethylamino)carbonyl]phenyl]hydroxy(3-methoxyphenyl)methyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester chemical structure, C29H40N2O5, CAS 209808-10-6](/s/DLHFPDSYUIXAGJ-UHFFFAOYSA-N.svg)
4-[[4-[(Diethylamino)carbonyl]phenyl]hydroxy(3-methoxyphenyl)methyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
CAS 209808-10-6C29H40N2O5
Bis(4-fluorophenyl)(piperidin-4-yl)methanol
CAS 60284-98-2C18H19F2NO
- N,N-Diethyl-4-[(2-methoxyphenyl)-4-piperidinylidenemethyl]benzamide209807-75-0C30H42N2O4
- 4-[Bis(4-fluorophenyl)methyl]piperidine60285-00-9C18H19F2N
- 4-[Bis(4-fluorophenyl)methyl]piperidine-1-carbaldehyde88780-58-9C19H19F2NO
- Methyl 4-[phenyl(piperidin-4-yl)methyl]benzoate88780-57-8C20H23NO2
- Methyl 4-[(1-formylpiperidin-4-yl)(phenyl)methyl]benzoate88780-59-0C21H23NO3
- 2,2-Diphenyl-2-(piperidin-4-yl)acetamide103887-43-0C19H22N2O
- {1-[2-(Methylamino)ethyl]piperidin-4-yl}(diphenyl)methanol121200-72-4C21H28N2O
- alpha,alpha-Bis(4-chlorophenyl)-4-piperidinemethanol67853-64-9C18H19Cl2NO
- 4-(Diphenylmethyl)-1-methylpiperidine5704-22-3C19H23N
- 4-(Diphenylmethyl)piperidine hydrochloride26344-73-0C18H22ClN
- 1-(3-Aminopropyl)-4-diphenylmethylpiperidine166809-82-1C21H28N2
- 4-[(4-Fluorophenyl)(phenyl)methyl]piperidine--hydrogen chloride (1/1)60285-02-1C18H21ClFN
- 1 suppliers4-(Diphenylmethyl)-1-nitrosopiperidine94067-39-7C18H20N2O
- tert-Butyl 4-(hydroxydiphenylmethyl)piperidine-1-carboxylate164650-64-0C23H29NO3
- 1,1-Dimethylethyl 4-(diphenylmethyl)-1-piperidinecarboxylate305794-67-6C23H29NO2
- 4-(Hydroxydiphenylmethyl)-1-piperidinesulfonyl fluoride1839621-42-9C18H20FNO3S
- 1-[4-(Hydroxydiphenylmethyl)piperidin-1-yl]prop-2-en-1-one2308161-33-1C21H23NO2
- 1-Nitrosopiperidin-4-yl)diphenylmethanol1038-06-8C18H20N2O2
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(P(c2ccccc2)c2ccccc2)cc1252 chemicals
c1ccc(C(c2ccccc2)c2ccccc2)cc1145 chemicals
c1ccc(C(c2ccccc2)N2CCNCC2)cc172 chemicals
c1ccc(N(c2ccccc2)c2ccccc2)cc147 chemicals![Scaffold [N+]=C1C=CC(=C(c2ccccc2)c2ccccc2)C=C1](/scaffold/ZMDDANKTRSYYRH-UHFFFAOYSA-N/structure.svg)
[N+]=C1C=CC(=C(c2ccccc2)c2ccccc2)C=C141 chemicals
O=C1C=CC(=C(c2ccccc2)c2ccccc2)C=C129 chemicalsc2ccccc2)cc1](/scaffold/AKQNYQDSIDKVJZ-UHFFFAOYSA-N/structure.svg)
c1ccc([SiH](c2ccccc2)c2ccccc2)cc123 chemicalsc2ccccc2)cc1](/scaffold/WLOQLWBIJZDHET-UHFFFAOYSA-N/structure.svg)
c1ccc([S+](c2ccccc2)c2ccccc2)cc123 chemicals
N=C1C=CC(=C(c2ccccc2)c2ccccc2)C=C121 chemicals
O=P(c1ccccc1)(c1ccccc1)c1ccccc119 chemicals
c1ccc(P(C2CCCCC2)C2CCCCC2)cc112 chemicals
C1CCC(P(C2CCCCC2)C2CCCCC2)CC112 chemicals