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Murcko scaffold

Ring system with 3 rings and 23 atoms

34 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
34
With full pages
4
Scaffold SMILES

O=C(Nc1cccs1)c1ccc(S(=O)(=O)N2CCCCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cccs1)c1ccc(S(=O)(=O)N2CCCCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 34 of 34 chemicals

Ethyl 4,5-dimethyl-2-(4-(piperidin-1-ylsulfonyl)benzamido)thiophene-3-carboxylate chemical structure, C21H26N2O5S2, CAS 325694-18-6
Ethyl 4,5-dimethyl-2-(4-(piperidin-1-ylsulfonyl)benzamido)thiophene-3-carboxylate
CAS 325694-18-6C21H26N2O5S2
Ethyl 5-acetyl-4-methyl-2-[(4-piperidin-1-ylsulfonylbenzoyl)amino]thiophene-3-carboxylate chemical structure, C22H26N2O6S2, CAS 342596-80-9
Ethyl 5-acetyl-4-methyl-2-[(4-piperidin-1-ylsulfonylbenzoyl)amino]thiophene-3-carboxylate
CAS 342596-80-9C22H26N2O6S2
N-(3-Cyanothiophen-2-yl)-4-piperidin-1-ylsulfonylbenzamide chemical structure, C17H17N3O3S2, CAS 865545-80-8
N-(3-Cyanothiophen-2-yl)-4-piperidin-1-ylsulfonylbenzamide
CAS 865545-80-8C17H17N3O3S2
2-(4-(Piperidin-1-ylsulfonyl)benzamido)thiophene-3-carboxamide chemical structure, C17H19N3O4S2, CAS 790245-59-9
2-(4-(Piperidin-1-ylsulfonyl)benzamido)thiophene-3-carboxamide
CAS 790245-59-9C17H19N3O4S2
Methyl (2-(4-(piperidin-1-ylsulfonyl)benzamido)thiophene-3-carbonyl)carbamate chemical structure, C19H21N3O6S2, CAS 864941-24-2
Methyl (2-(4-(piperidin-1-ylsulfonyl)benzamido)thiophene-3-carbonyl)carbamate
CAS 864941-24-2C19H21N3O6S2
Ethyl 2-(4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamido)-5-nitrothiophene-3-carboxylate chemical structure, C21H25N3O7S2, CAS 477537-16-9
Ethyl 2-(4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamido)-5-nitrothiophene-3-carboxylate
CAS 477537-16-9C21H25N3O7S2
Ethyl 5-nitro-2-(4-(piperidin-1-ylsulfonyl)benzamido)thiophene-3-carboxylate chemical structure, C19H21N3O7S2, CAS 477490-96-3
Ethyl 5-nitro-2-(4-(piperidin-1-ylsulfonyl)benzamido)thiophene-3-carboxylate
CAS 477490-96-3C19H21N3O7S2
Diethyl 5-(4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamido)-3-methylthiophene-2,4-dicarboxylate chemical structure, C25H32N2O7S2, CAS 391867-49-5
Diethyl 5-(4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamido)-3-methylthiophene-2,4-dicarboxylate
CAS 391867-49-5C25H32N2O7S2
Ethyl 2-(4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamido)-4,5-dimethylthiophene-3-carboxylate chemical structure, C23H30N2O5S2, CAS 392323-83-0
Ethyl 2-(4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamido)-4,5-dimethylthiophene-3-carboxylate
CAS 392323-83-0C23H30N2O5S2
2-(4-((4-Methylpiperidin-1-yl)sulfonyl)benzamido)thiophene-3-carboxamide chemical structure, C18H21N3O4S2, CAS 864940-96-5
2-(4-((4-Methylpiperidin-1-yl)sulfonyl)benzamido)thiophene-3-carboxamide
CAS 864940-96-5C18H21N3O4S2
N-Methyl-2-(4-((4-methylpiperidin-1-yl)sulfonyl)benzamido)thiophene-3-carboxamide chemical structure, C19H23N3O4S2, CAS 888413-39-6
N-Methyl-2-(4-((4-methylpiperidin-1-yl)sulfonyl)benzamido)thiophene-3-carboxamide
CAS 888413-39-6C19H23N3O4S2
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide chemical structure, C19H21N3O3S2, CAS 896301-30-7
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide
CAS 896301-30-7C19H21N3O3S2
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-4-(4-methylpiperidin-1-yl)sulfonylbenzamide chemical structure, C20H23N3O3S2, CAS 896303-54-1
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-4-(4-methylpiperidin-1-yl)sulfonylbenzamide
CAS 896303-54-1C20H23N3O3S2
4,5-Dimethyl-2-(4-(piperidin-1-ylsulfonyl)benzamido)thiophene-3-carboxamide chemical structure, C19H23N3O4S2, CAS 896307-10-1
4,5-Dimethyl-2-(4-(piperidin-1-ylsulfonyl)benzamido)thiophene-3-carboxamide
CAS 896307-10-1C19H23N3O4S2
2-(4-((3,5-Dimethylpiperidin-1-yl)sulfonyl)benzamido)thiophene-3-carboxamide chemical structure, C19H23N3O4S2, CAS 864940-91-0
2-(4-((3,5-Dimethylpiperidin-1-yl)sulfonyl)benzamido)thiophene-3-carboxamide
CAS 864940-91-0C19H23N3O4S2
2-(4-((2-Methylpiperidin-1-yl)sulfonyl)benzamido)thiophene-3-carboxamide chemical structure, C18H21N3O4S2, CAS 864940-97-6
2-(4-((2-Methylpiperidin-1-yl)sulfonyl)benzamido)thiophene-3-carboxamide
CAS 864940-97-6C18H21N3O4S2
2-(4-((3-Methylpiperidin-1-yl)sulfonyl)benzamido)thiophene-3-carboxamide chemical structure, C18H21N3O4S2, CAS 888413-15-8
2-(4-((3-Methylpiperidin-1-yl)sulfonyl)benzamido)thiophene-3-carboxamide
CAS 888413-15-8C18H21N3O4S2
2-{4-[(2-Ethylpiperidin-1-yl)sulfonyl]benzamido}thiophene-3-carboxamide chemical structure, C19H23N3O4S2, CAS 864941-13-9
2-{4-[(2-Ethylpiperidin-1-yl)sulfonyl]benzamido}thiophene-3-carboxamide
CAS 864941-13-9C19H23N3O4S2
2-{4-[(3,5-Dimethylpiperidin-1-yl)sulfonyl]benzamido}-N-methylthiophene-3-carboxamide chemical structure, C20H25N3O4S2, CAS 888413-36-3
2-{4-[(3,5-Dimethylpiperidin-1-yl)sulfonyl]benzamido}-N-methylthiophene-3-carboxamide
CAS 888413-36-3C20H25N3O4S2
N-Methyl-2-{4-[(3-methylpiperidin-1-yl)sulfonyl]benzamido}thiophene-3-carboxamide chemical structure, C19H23N3O4S2, CAS 888413-40-9
N-Methyl-2-{4-[(3-methylpiperidin-1-yl)sulfonyl]benzamido}thiophene-3-carboxamide
CAS 888413-40-9C19H23N3O4S2
N-Methyl-2-{4-[(2-methylpiperidin-1-yl)sulfonyl]benzamido}thiophene-3-carboxamide chemical structure, C19H23N3O4S2, CAS 888413-41-0
N-Methyl-2-{4-[(2-methylpiperidin-1-yl)sulfonyl]benzamido}thiophene-3-carboxamide
CAS 888413-41-0C19H23N3O4S2
2-(4-((2-Ethylpiperidin-1-yl)sulfonyl)benzamido)-N-methylthiophene-3-carboxamide chemical structure, C20H25N3O4S2, CAS 888413-48-7
2-(4-((2-Ethylpiperidin-1-yl)sulfonyl)benzamido)-N-methylthiophene-3-carboxamide
CAS 888413-48-7C20H25N3O4S2
N,4,5-trimethyl-2-(4-(piperidin-1-ylsulfonyl)benzamido)thiophene-3-carboxamide chemical structure, C20H25N3O4S2, CAS 896293-86-0
N,4,5-trimethyl-2-(4-(piperidin-1-ylsulfonyl)benzamido)thiophene-3-carboxamide
CAS 896293-86-0C20H25N3O4S2
4,5-Dimethyl-2-(4-((3-methylpiperidin-1-yl)sulfonyl)benzamido)thiophene-3-carboxamide chemical structure, C20H25N3O4S2, CAS 896309-34-5
4,5-Dimethyl-2-(4-((3-methylpiperidin-1-yl)sulfonyl)benzamido)thiophene-3-carboxamide
CAS 896309-34-5C20H25N3O4S2