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Murcko scaffold

Ring system with 3 rings and 20 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
10
With full pages
7
Scaffold SMILES

C(=NN1CCN(Cc2ccccc2)CC1)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=NN1CCN(Cc2ccccc2)CC1)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

4-(4-Methylbenzyl)-N-[(5-methyl-2-thienyl)methylene]-1-piperazinamine chemical structure, C18H23N3S, CAS 315223-27-9
4-(4-Methylbenzyl)-N-[(5-methyl-2-thienyl)methylene]-1-piperazinamine
CAS 315223-27-9C18H23N3S
N-((5-Bromo-2-thienyl)methylene)-4-(4-chlorobenzyl)-1-piperazinamine chemical structure, C16H17BrClN3S, CAS 303105-27-3
N-((5-Bromo-2-thienyl)methylene)-4-(4-chlorobenzyl)-1-piperazinamine
CAS 303105-27-3C16H17BrClN3S
N-((5-Bromo-2-thienyl)methylene)-4-(4-methylbenzyl)-1-piperazinamine chemical structure, C17H20BrN3S, CAS 303102-28-5
N-((5-Bromo-2-thienyl)methylene)-4-(4-methylbenzyl)-1-piperazinamine
CAS 303102-28-5C17H20BrN3S
4-(4-Chlorobenzyl)-N-((5-methyl-2-thienyl)methylene)-1-piperazinamine chemical structure, C17H20ClN3S, CAS 315224-00-1
4-(4-Chlorobenzyl)-N-((5-methyl-2-thienyl)methylene)-1-piperazinamine
CAS 315224-00-1C17H20ClN3S
N-{4-[(2,4-Dimethylphenyl)methyl]piperazin-1-yl}-1-(3-methylthiophen-2-yl)methanimine chemical structure, C19H25N3S, CAS 315184-78-2
N-{4-[(2,4-Dimethylphenyl)methyl]piperazin-1-yl}-1-(3-methylthiophen-2-yl)methanimine
CAS 315184-78-2C19H25N3S
4-(2-Chlorobenzyl)-N-((5-methyl-2-thienyl)methylene)-1-piperazinamine chemical structure, C17H20ClN3S, CAS 315213-53-7
4-(2-Chlorobenzyl)-N-((5-methyl-2-thienyl)methylene)-1-piperazinamine
CAS 315213-53-7C17H20ClN3S
4-(4-Chlorobenzyl)-N-[(E)-(3-methyl-2-thienyl)methylidene]-1-piperazinamine chemical structure, C17H20ClN3S, CAS 306989-25-3
4-(4-Chlorobenzyl)-N-[(E)-(3-methyl-2-thienyl)methylidene]-1-piperazinamine
CAS 306989-25-3C17H20ClN3S
4-(4-Chlorobenzyl)-N-(2-thienylmethylene)-1-piperazinamine chemical structure, C16H18ClN3S, CAS 306989-77-5
4-(4-Chlorobenzyl)-N-(2-thienylmethylene)-1-piperazinamine
CAS 306989-77-5C16H18ClN3S
4-Benzyl-N-((5-bromo-2-thienyl)methylene)-1-piperazinamine chemical structure, C16H18BrN3S, CAS 303092-67-3
4-Benzyl-N-((5-bromo-2-thienyl)methylene)-1-piperazinamine
CAS 303092-67-3C16H18BrN3S
4-Benzyl-N-((5-methyl-2-thienyl)methylene)-1-piperazinamine chemical structure, C17H21N3S, CAS 499211-74-4
4-Benzyl-N-((5-methyl-2-thienyl)methylene)-1-piperazinamine
CAS 499211-74-4C17H21N3S