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Murcko scaffold

Ring system with 4 rings and 23 atoms

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
12
With full pages
5
Scaffold SMILES

O=C(c1ccco1)N1N=C(c2ccccc2)CC1c1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccco1)N1N=C(c2ccccc2)CC1c1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

[5-(3,4-Dimethoxyphenyl)-3-(furan-2-yl)-3,4-dihydropyrazol-2-yl]-(furan-2-yl)methanone chemical structure, C20H18N2O5, CAS 701227-64-7
[5-(3,4-Dimethoxyphenyl)-3-(furan-2-yl)-3,4-dihydropyrazol-2-yl]-(furan-2-yl)methanone
CAS 701227-64-7C20H18N2O5
(5-Bromofuran-2-yl)-[5-(4-chlorophenyl)-3-(furan-2-yl)-3,4-dihydropyrazol-2-yl]methanone chemical structure, C18H12BrClN2O3, CAS 500275-06-9
(5-Bromofuran-2-yl)-[5-(4-chlorophenyl)-3-(furan-2-yl)-3,4-dihydropyrazol-2-yl]methanone
CAS 500275-06-9C18H12BrClN2O3
Furan-2-yl-[3-(furan-2-yl)-5-(3-methoxyphenyl)-3,4-dihydropyrazol-2-yl]methanone chemical structure, C19H16N2O4, CAS 710985-97-0
Furan-2-yl-[3-(furan-2-yl)-5-(3-methoxyphenyl)-3,4-dihydropyrazol-2-yl]methanone
CAS 710985-97-0C19H16N2O4
N-{4-[5-(Furan-2-yl)-1-(furan-2-ylcarbonyl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl}methanesulfonamide chemical structure, C19H17N3O5S, CAS 833440-89-4
N-{4-[5-(Furan-2-yl)-1-(furan-2-ylcarbonyl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl}methanesulfonamide
CAS 833440-89-4C19H17N3O5S
(3-(4-Chlorophenyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)(furan-2-yl)methanone chemical structure, C18H13ClN2O3, CAS 489413-54-9
(3-(4-Chlorophenyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)(furan-2-yl)methanone
CAS 489413-54-9C18H13ClN2O3
3-[1-(Furan-2-carbonyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-3-yl]phenol chemical structure, C18H14N2O4, CAS 927625-53-4
3-[1-(Furan-2-carbonyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-3-yl]phenol
CAS 927625-53-4C18H14N2O4
N-(4-(5-(5-Chlorofuran-2-yl)-1-(furan-2-carbonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C20H18ClN3O5S, CAS 876942-68-6
N-(4-(5-(5-Chlorofuran-2-yl)-1-(furan-2-carbonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 876942-68-6C20H18ClN3O5S
1-(Furan-2-carbonyl)-5-(furan-2-yl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole chemical structure, C19H16N2O4, CAS 927137-56-2
1-(Furan-2-carbonyl)-5-(furan-2-yl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole
CAS 927137-56-2C19H16N2O4
N-(3-(1-(Furan-2-carbonyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)acetamide chemical structure, C20H17N3O4, CAS 927145-30-0
N-(3-(1-(Furan-2-carbonyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)acetamide
CAS 927145-30-0C20H17N3O4
N-(4-(1-(Furan-2-carbonyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)acetamide chemical structure, C20H17N3O4, CAS 927145-36-6
N-(4-(1-(Furan-2-carbonyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)acetamide
CAS 927145-36-6C20H17N3O4
N-{3-[1-(5-Bromofuran-2-carbonyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl}ethane-1-sulfonamide chemical structure, C20H18BrN3O5S, CAS 941913-14-0
N-{3-[1-(5-Bromofuran-2-carbonyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl}ethane-1-sulfonamide
CAS 941913-14-0C20H18BrN3O5S
(5-Bromofuran-2-yl)(5-(furan-2-yl)-3-(2-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methanone chemical structure, C18H13BrN2O4, CAS 946378-90-1
(5-Bromofuran-2-yl)(5-(furan-2-yl)-3-(2-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methanone
CAS 946378-90-1C18H13BrN2O4