CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 23 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
9
With full pages
4
Scaffold SMILES

O=C(c1ccco1)N1N=C(c2ccccc2)CC1c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccco1)N1N=C(c2ccccc2)CC1c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

N-{3-[1-(Furan-2-carbonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl}methanesulfonamide chemical structure, C19H17N3O4S2, CAS 714263-36-2
N-{3-[1-(Furan-2-carbonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl}methanesulfonamide
CAS 714263-36-2C19H17N3O4S2
N-(4-(1-(Furan-2-carbonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide chemical structure, C19H17N3O4S2, CAS 851718-30-4
N-(4-(1-(Furan-2-carbonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
CAS 851718-30-4C19H17N3O4S2
[5-(3,4-Dimethoxyphenyl)-3-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-(furan-2-yl)methanone chemical structure, C20H18N2O4S, CAS 836635-03-1
[5-(3,4-Dimethoxyphenyl)-3-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-(furan-2-yl)methanone
CAS 836635-03-1C20H18N2O4S
N-(3-(1-(Furan-2-carbonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)acetamide chemical structure, C20H17N3O3S, CAS 927145-24-2
N-(3-(1-(Furan-2-carbonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)acetamide
CAS 927145-24-2C20H17N3O3S
N-(4-(1-(Furan-2-carbonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide chemical structure, C20H19N3O4S2, CAS 852141-53-8
N-(4-(1-(Furan-2-carbonyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)ethanesulfonamide
CAS 852141-53-8C20H19N3O4S2
3-(4-Fluorophenyl)-1-(furan-2-carbonyl)-5-(3-methylthiophen-2-yl)-4,5-dihydro-1H-pyrazole chemical structure, C19H15FN2O2S, CAS 1018050-83-3
3-(4-Fluorophenyl)-1-(furan-2-carbonyl)-5-(3-methylthiophen-2-yl)-4,5-dihydro-1H-pyrazole
CAS 1018050-83-3C19H15FN2O2S
(3-(2,4-Dimethoxyphenyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)(furan-2-yl)methanone chemical structure, C20H18N2O4S, CAS 1448046-05-6
(3-(2,4-Dimethoxyphenyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)(furan-2-yl)methanone
CAS 1448046-05-6C20H18N2O4S
(3-(4-Fluorophenyl)-5-(5-methylthiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)(furan-2-yl)methanone chemical structure, C19H15FN2O2S, CAS 1808404-19-4
(3-(4-Fluorophenyl)-5-(5-methylthiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)(furan-2-yl)methanone
CAS 1808404-19-4C19H15FN2O2S
Furan-2-yl(3-(2-hydroxyphenyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)methanone chemical structure, C18H14N2O3S, CAS 876941-51-4
Furan-2-yl(3-(2-hydroxyphenyl)-5-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)methanone
CAS 876941-51-4C18H14N2O3S