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Murcko scaffold

Ring system with 4 rings and 24 atoms

7 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
7
With full pages
3
Scaffold SMILES

c1ccc2c(CCCN3CCN(c4ccncn4)CC3)c[nH]c2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc2c(CCCN3CCN(c4ccncn4)CC3)c[nH]c2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

Avitriptan chemical structure, C22H30N6O3S, CAS 151140-96-4
Avitriptan
CAS 151140-96-4C22H30N6O3S
Bms 181101 chemical structure, C20H26Cl2FN5O, CAS 146479-45-0
Bms 181101
CAS 146479-45-0C20H26Cl2FN5O
BMS-181101 free base chemical structure, C20H24FN5O, CAS 141071-67-2
BMS-181101 free base
CAS 141071-67-2C20H24FN5O
Avitriptan fumarate chemical structure, C26H34N6O7S, CAS 171171-42-9
Avitriptan fumarate
CAS 171171-42-9C26H34N6O7S
1-[3-[3-[4-(5-Methoxypyrimidin-4-yl)piperazin-1-yl]propyl]-1H-indol-5-yl]-N-methylmethanesulfonamide, hydrochloride chemical structure, C22H31ClN6O3S, CAS 191588-96-2
1-[3-[3-[4-(5-Methoxypyrimidin-4-yl)piperazin-1-yl]propyl]-1H-indol-5-yl]-N-methylmethanesulfonamide, hydrochloride
CAS 191588-96-2C22H31ClN6O3S
1-[3-{3-[4-(5-Methoxypyrimidin-4-yl)piperazin-1-yl]propyl}-2-(trimethylsilyl)-1H-indol-5-yl]-N-methylmethanesulfonamide chemical structure, C25H38N6O3SSi, CAS 191588-95-1
1-[3-{3-[4-(5-Methoxypyrimidin-4-yl)piperazin-1-yl]propyl}-2-(trimethylsilyl)-1H-indol-5-yl]-N-methylmethanesulfonamide
CAS 191588-95-1C25H38N6O3SSi
Orb1739223 chemical structure, C22H32Cl2N6O3S, CAS 170956-82-8
Orb1739223
CAS 170956-82-8C22H32Cl2N6O3S