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Murcko scaffold

3-(1H-Indol-3-yl)-1-(4-phenylpiperazin-1-yl)propan-1-one scaffold

4 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
4
With full pages
1
Scaffold SMILES

O=C(CCc1c[nH]c2ccccc12)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-(1H-Indol-3-yl)-1-(4-phenylpiperazin-1-yl)propan-1-one page
Murcko scaffold O=C(CCc1c[nH]c2ccccc12)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

1-[4-(3-Chlorophenyl)piperazin-1-yl]-3-(1H-indol-3-yl)propan-1-one chemical structure, C21H22ClN3O, CAS 732994-42-2
1-[4-(3-Chlorophenyl)piperazin-1-yl]-3-(1H-indol-3-yl)propan-1-one
CAS 732994-42-2C21H22ClN3O
3-(1H-Indol-3-yl)-1-(4-phenylpiperazin-1-yl)propan-1-one chemical structure, C21H23N3O, CAS 94918-71-5
3-(1H-Indol-3-yl)-1-(4-phenylpiperazin-1-yl)propan-1-one
CAS 94918-71-5C21H23N3O
3-(1H-Indol-3-yl)-1-[4-(4-methoxyphenyl)piperazin-1-yl]propan-1-one chemical structure, C22H25N3O2, CAS 746633-18-1
3-(1H-Indol-3-yl)-1-[4-(4-methoxyphenyl)piperazin-1-yl]propan-1-one
CAS 746633-18-1C22H25N3O2
1-[beta-(2-Methyl-3-indolyl)propionyl]-4-phenylpiperazine chemical structure, C22H25N3O, CAS 34803-70-8
1-[beta-(2-Methyl-3-indolyl)propionyl]-4-phenylpiperazine
CAS 34803-70-8C22H25N3O