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Murcko scaffold

Ring system with 3 rings and 13 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
13
Chemicals
9
With full pages
1
Scaffold SMILES

c1ccc(N2CC3(COC3)C2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(N2CC3(COC3)C2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

5-Nitro-2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)benzonitrile chemical structure, C12H11N3O3, CAS 1467037-16-6
5-Nitro-2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)benzonitrile
CAS 1467037-16-6C12H11N3O3
4-(2-Oxa-6-azaspiro[3.3]heptan-6-yl)aniline chemical structure, C11H14N2O, CAS 1416369-77-1
4-(2-Oxa-6-azaspiro[3.3]heptan-6-yl)aniline
CAS 1416369-77-1C11H14N2O
6-(2-Methoxy-4-nitrophenyl)-2-oxa-6-azaspiro[3.3]heptane chemical structure, C12H14N2O4, CAS 1453213-46-1
6-(2-Methoxy-4-nitrophenyl)-2-oxa-6-azaspiro[3.3]heptane
CAS 1453213-46-1C12H14N2O4
6-(4-Nitrophenyl)-2-oxa-6-azaspiro[3.3]heptane chemical structure, C11H12N2O3, CAS 1527519-84-1
6-(4-Nitrophenyl)-2-oxa-6-azaspiro[3.3]heptane
CAS 1527519-84-1C11H12N2O3
6-(2-Fluoro-4-nitrophenyl)-2-oxa-6-azaspiro[3.3]heptane chemical structure, C11H11FN2O3, CAS 1975218-55-3
6-(2-Fluoro-4-nitrophenyl)-2-oxa-6-azaspiro[3.3]heptane
CAS 1975218-55-3C11H11FN2O3
3-Fluoro-4-(2-oxa-6-azaspiro[3.3]heptan-6-yl)aniline chemical structure, C11H13FN2O, CAS 1975218-56-4
3-Fluoro-4-(2-oxa-6-azaspiro[3.3]heptan-6-yl)aniline
CAS 1975218-56-4C11H13FN2O
4-(2-Oxa-6-azaspiro[3.3]heptan-6-yl)benzoic acid chemical structure, C12H13NO3, CAS 2162769-30-2
4-(2-Oxa-6-azaspiro[3.3]heptan-6-yl)benzoic acid
CAS 2162769-30-2C12H13NO3
4-(2-Oxa-6-azaspiro(3.3)heptan-6-yl)benzaldehyde chemical structure, C12H13NO2, CAS 2104588-69-2
4-(2-Oxa-6-azaspiro(3.3)heptan-6-yl)benzaldehyde
CAS 2104588-69-2C12H13NO2
2-{2-Oxa-6-azaspiro[3.3]heptan-6-yl}benzaldehyde chemical structure, C12H13NO2, CAS 2103989-22-4
2-{2-Oxa-6-azaspiro[3.3]heptan-6-yl}benzaldehyde
CAS 2103989-22-4C12H13NO2