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Murcko scaffold

Ring system with 3 rings and 13 atoms

36 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 13
Chemicals: 36
With full pages: 2

Scaffold SMILES

c1ccc(C2CC3(COC3)C2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1ccc(C2CC3(COC3)C2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 36 of 36 chemicals

6-Phenyl-2-oxa-spiro[3.3]heptane-6-carbonitrile chemical structure, C13H13NO, CAS 1414513-75-9

6-Phenyl-2-oxa-spiro[3.3]heptane-6-carbonitrile

CAS 1414513-75-9C₁₃H₁₃NO

6-(3-Chloro-2-fluorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile chemical structure, C13H11ClFNO, CAS 1555436-90-2

6-(3-Chloro-2-fluorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile

CAS 1555436-90-2C₁₃H₁₁ClFNO

6-(2,6-Dichlorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile chemical structure, C13H11Cl2NO, CAS 1551800-94-2

6-(2,6-Dichlorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile

CAS 1551800-94-2C₁₃H₁₁Cl₂NO

6-(4-Methoxyphenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile chemical structure, C14H15NO2, CAS 1548557-61-4

6-(4-Methoxyphenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile

CAS 1548557-61-4C₁₄H₁₅NO₂

6-(2-Methoxyphenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile chemical structure, C14H15NO2, CAS 1551800-98-6

6-(2-Methoxyphenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile

CAS 1551800-98-6C₁₄H₁₅NO₂

6-(3,5-Dimethylphenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile chemical structure, C15H17NO, CAS 1553319-95-1

6-(3,5-Dimethylphenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile

CAS 1553319-95-1C₁₅H₁₇NO

6-(2-Methylphenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile chemical structure, C14H15NO, CAS 1545547-22-5

6-(2-Methylphenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile

CAS 1545547-22-5C₁₄H₁₅NO

6-(3-Chlorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile chemical structure, C13H12ClNO, CAS 1551918-59-2

6-(3-Chlorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile

CAS 1551918-59-2C₁₃H₁₂ClNO

6-(4-Chlorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile chemical structure, C13H12ClNO, CAS 1401895-24-6

6-(4-Chlorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile

CAS 1401895-24-6C₁₃H₁₂ClNO

6-[4-(Difluoromethoxy)phenyl]-2-oxaspiro[3.3]heptane-6-carbonitrile chemical structure, C14H13F2NO2, CAS 1549307-21-2

6-[4-(Difluoromethoxy)phenyl]-2-oxaspiro[3.3]heptane-6-carbonitrile

CAS 1549307-21-2C₁₄H₁₃F₂NO₂

6-[3-(Trifluoromethyl)phenyl]-2-oxaspiro[3.3]heptane-6-carbonitrile chemical structure, C14H12F3NO, CAS 1548557-65-8

6-[3-(Trifluoromethyl)phenyl]-2-oxaspiro[3.3]heptane-6-carbonitrile

CAS 1548557-65-8C₁₄H₁₂F₃NO

6-(4-Fluorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile chemical structure, C13H12FNO, CAS 1549307-28-9

6-(4-Fluorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile

CAS 1549307-28-9C₁₃H₁₂FNO

6-(3,4-Dichlorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile chemical structure, C13H11Cl2NO, CAS 1550302-85-6

6-(3,4-Dichlorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile

CAS 1550302-85-6C₁₃H₁₁Cl₂NO

6-(4-Methylphenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile chemical structure, C14H15NO, CAS 1545412-89-2

6-(4-Methylphenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile

CAS 1545412-89-2C₁₄H₁₅NO

6-(2-Chloro-4-fluorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile chemical structure, C13H11ClFNO, CAS 1545590-37-1

6-(2-Chloro-4-fluorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile

CAS 1545590-37-1C₁₃H₁₁ClFNO

6-(2,4-Difluorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile chemical structure, C13H11F2NO, CAS 1546920-74-4

6-(2,4-Difluorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile

CAS 1546920-74-4C₁₃H₁₁F₂NO

6-Phenyl-2-oxaspiro[3.3]heptane-6-carboxylic acid chemical structure, C13H14O3, CAS 2098119-94-7

6-Phenyl-2-oxaspiro[3.3]heptane-6-carboxylic acid

CAS 2098119-94-7C₁₃H₁₄O₃

(6-Phenyl-2-oxaspiro[3.3]heptan-6-yl)methanol chemical structure, C13H16O2, CAS 2098069-36-2

(6-Phenyl-2-oxaspiro[3.3]heptan-6-yl)methanol

CAS 2098069-36-2C₁₃H₁₆O₂

(6-Phenyl-2-oxaspiro[3.3]heptan-6-yl)methanamine chemical structure, C13H17NO, CAS 2097963-89-6

(6-Phenyl-2-oxaspiro[3.3]heptan-6-yl)methanamine

CAS 2097963-89-6C₁₃H₁₇NO

6-Phenyl-2-oxaspiro[3.3]heptan-6-amine chemical structure, C12H15NO, CAS 1936095-09-8

6-Phenyl-2-oxaspiro[3.3]heptan-6-amine

CAS 1936095-09-8C₁₂H₁₅NO

6-(3,5-Dimethoxyphenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile chemical structure, C15H17NO3, CAS 2825012-69-7

6-(3,5-Dimethoxyphenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile

CAS 2825012-69-7C₁₅H₁₇NO₃

6-(5-Chloro-2-fluorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile chemical structure, C13H11ClFNO, CAS 2825012-01-7

6-(5-Chloro-2-fluorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile

CAS 2825012-01-7C₁₃H₁₁ClFNO

6-(4-Bromo-3-fluorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile chemical structure, C13H11BrFNO, CAS 2839138-60-0

6-(4-Bromo-3-fluorophenyl)-2-oxaspiro[3.3]heptane-6-carbonitrile

CAS 2839138-60-0C₁₃H₁₁BrFNO

Lithium(1+) 6-phenyl-2-oxaspiro[3.3]heptane-6-carboxylate chemical structure, C13H13LiO3, CAS 2680537-65-7

Lithium(1+) 6-phenyl-2-oxaspiro[3.3]heptane-6-carboxylate

CAS 2680537-65-7C₁₃H₁₃LiO₃