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Murcko scaffold

Ring system with 3 rings and 24 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
12
With full pages
10
Scaffold SMILES

O=C(C=Cc1ccco1)N(Cc1ccccc1)C1CCS(=O)(=O)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccco1)N(Cc1ccccc1)C1CCS(=O)(=O)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

(2E)-N-[4-(Dimethylamino)benzyl]-N-(1,1-dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)prop-2-enamide chemical structure, C20H24N2O4S, CAS 620572-05-6
(2E)-N-[4-(Dimethylamino)benzyl]-N-(1,1-dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)prop-2-enamide
CAS 620572-05-6C20H24N2O4S
(2E)-N-(3-Bromobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)prop-2-enamide chemical structure, C18H18BrNO4S, CAS 872455-61-3
(2E)-N-(3-Bromobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)prop-2-enamide
CAS 872455-61-3C18H18BrNO4S
(2E)-N-(2-Chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)prop-2-enamide chemical structure, C18H18ClNO4S, CAS 578758-79-9
(2E)-N-(2-Chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)prop-2-enamide
CAS 578758-79-9C18H18ClNO4S
(2E)-N-Benzyl-N-(1,1-dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)prop-2-enamide chemical structure, C18H19NO4S, CAS 577961-47-8
(2E)-N-Benzyl-N-(1,1-dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)prop-2-enamide
CAS 577961-47-8C18H19NO4S
(E)-N-(3-Chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)acrylamide chemical structure, C18H18ClNO4S, CAS 578719-38-7
(E)-N-(3-Chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)acrylamide
CAS 578719-38-7C18H18ClNO4S
(2E)-N-(4-Chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)prop-2-enamide chemical structure, C18H18ClNO4S, CAS 578763-16-3
(2E)-N-(4-Chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)prop-2-enamide
CAS 578763-16-3C18H18ClNO4S
(2E)-N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-fluorobenzyl)-3-(furan-2-yl)prop-2-enamide chemical structure, C18H18FNO4S, CAS 848064-06-2
(2E)-N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-fluorobenzyl)-3-(furan-2-yl)prop-2-enamide
CAS 848064-06-2C18H18FNO4S
(2E)-N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-ethoxybenzyl)-3-(furan-2-yl)prop-2-enamide chemical structure, C20H23NO5S, CAS 845663-03-8
(2E)-N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-ethoxybenzyl)-3-(furan-2-yl)prop-2-enamide
CAS 845663-03-8C20H23NO5S
(2E)-N-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)-N-(4-methoxybenzyl)prop-2-enamide chemical structure, C19H21NO5S, CAS 585562-09-0
(2E)-N-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)-N-(4-methoxybenzyl)prop-2-enamide
CAS 585562-09-0C19H21NO5S
(2E)-N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-ethylbenzyl)-3-(furan-2-yl)prop-2-enamide chemical structure, C20H23NO4S, CAS 620570-24-3
(2E)-N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-ethylbenzyl)-3-(furan-2-yl)prop-2-enamide
CAS 620570-24-3C20H23NO4S
(2E)-N-(3,4-Dimethoxybenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)prop-2-enamide chemical structure, C20H23NO6S, CAS 620570-82-3
(2E)-N-(3,4-Dimethoxybenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)prop-2-enamide
CAS 620570-82-3C20H23NO6S
(2E)-N-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)-N-[4-(propan-2-yl)benzyl]prop-2-enamide chemical structure, C21H25NO4S, CAS 620571-43-9
(2E)-N-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-(furan-2-yl)-N-[4-(propan-2-yl)benzyl]prop-2-enamide
CAS 620571-43-9C21H25NO4S