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Murcko scaffold

Ring system with 2 rings and 16 atoms

22 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
22
With full pages
3
Scaffold SMILES

O=C(C=Cc1cccnc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1cccnc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

1-(2-Hydroxyphenyl)-3-(pyridin-3-yl)prop-2-en-1-one chemical structure, C14H11NO2, CAS 2875-25-4
1-(2-Hydroxyphenyl)-3-(pyridin-3-yl)prop-2-en-1-one
CAS 2875-25-4C14H11NO2
2-Propen-1-one, 1-(4-methoxyphenyl)-3-(3-pyridinyl)- chemical structure, C15H13NO2, CAS 63856-02-0
2-Propen-1-one, 1-(4-methoxyphenyl)-3-(3-pyridinyl)-
CAS 63856-02-0C15H13NO2
2-Propen-1-one, 1-(4-nitrophenyl)-3-(3-pyridinyl)- chemical structure, C14H10N2O3, CAS 64908-82-3
2-Propen-1-one, 1-(4-nitrophenyl)-3-(3-pyridinyl)-
CAS 64908-82-3C14H10N2O3
(E)-1-Phenyl-3-pyridin-3-ylprop-2-en-1-one chemical structure, C14H11NO, CAS 4452-13-5
(E)-1-Phenyl-3-pyridin-3-ylprop-2-en-1-one
CAS 4452-13-5C14H11NO
(E)-1-(2-Hydroxyphenyl)-3-pyridin-3-ylprop-2-en-1-one chemical structure, C14H11NO2, CAS 908563-68-8
(E)-1-(2-Hydroxyphenyl)-3-pyridin-3-ylprop-2-en-1-one
CAS 908563-68-8C14H11NO2
(2E)-1-(2-Hydroxy-4-methoxyphenyl)-3-(pyridin-3-yl)prop-2-EN-1-one chemical structure, C15H13NO3, CAS 6622-61-3
(2E)-1-(2-Hydroxy-4-methoxyphenyl)-3-(pyridin-3-yl)prop-2-EN-1-one
CAS 6622-61-3C15H13NO3
1-(5-Chloro-2-hydroxyphenyl)-3-(3-pyridyl)prop-2-en-1-one chemical structure, C14H10ClNO2, CAS 1218-25-3
1-(5-Chloro-2-hydroxyphenyl)-3-(3-pyridyl)prop-2-en-1-one
CAS 1218-25-3C14H10ClNO2
1-(3,4-Dimethoxyphenyl)-3-(3-pyridinyl)-2-propen-1-one chemical structure, C16H15NO3, CAS 878581-46-5
1-(3,4-Dimethoxyphenyl)-3-(3-pyridinyl)-2-propen-1-one
CAS 878581-46-5C16H15NO3
(E)-1-(5-Bromo-2-hydroxyphenyl)-3-pyridin-3-ylprop-2-en-1-one chemical structure, C14H10BrNO2, CAS 220633-84-1
(E)-1-(5-Bromo-2-hydroxyphenyl)-3-pyridin-3-ylprop-2-en-1-one
CAS 220633-84-1C14H10BrNO2
(E)-1-(5-Fluoro-2-hydroxyphenyl)-3-pyridin-3-ylprop-2-en-1-one chemical structure, C14H10FNO2, CAS 220633-85-2
(E)-1-(5-Fluoro-2-hydroxyphenyl)-3-pyridin-3-ylprop-2-en-1-one
CAS 220633-85-2C14H10FNO2
(E)-1-(4-Hydroxyphenyl)-3-pyridin-3-ylprop-2-en-1-one chemical structure, C14H11NO2, CAS 315681-44-8
(E)-1-(4-Hydroxyphenyl)-3-pyridin-3-ylprop-2-en-1-one
CAS 315681-44-8C14H11NO2
Acrylophenone, 3'-amino-3-(3-pyridyl)- chemical structure, C14H12N2O, CAS 64908-86-7
Acrylophenone, 3'-amino-3-(3-pyridyl)-
CAS 64908-86-7C14H12N2O
Acrylophenone, 4'-amino-3-(3-pyridyl)- chemical structure, C14H12N2O, CAS 64908-88-9
Acrylophenone, 4'-amino-3-(3-pyridyl)-
CAS 64908-88-9C14H12N2O
2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(3-pyridinyl) chemical structure, C16H15NO4, CAS 76554-26-2
2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(3-pyridinyl)
CAS 76554-26-2C16H15NO4
1-(4-Bromophenyl)-3-(pyridin-3-yl)prop-2-en-1-one chemical structure, C14H10BrNO, CAS 54313-82-5
1-(4-Bromophenyl)-3-(pyridin-3-yl)prop-2-en-1-one
CAS 54313-82-5C14H10BrNO
4-[(E)-3-(2-Chloro-3-pyridinyl)prop-2-enoyl]-N-methylbenzenesulfonamide chemical structure, C15H13ClN2O3S, CAS 1424663-48-8
4-[(E)-3-(2-Chloro-3-pyridinyl)prop-2-enoyl]-N-methylbenzenesulfonamide
CAS 1424663-48-8C15H13ClN2O3S
3-(2-Chloropyridin-3-yl)-1-(3-fluoro-4-methanesulfonylphenyl)prop-2-en-1-one chemical structure, C15H11ClFNO3S, CAS 1424629-02-6
3-(2-Chloropyridin-3-yl)-1-(3-fluoro-4-methanesulfonylphenyl)prop-2-en-1-one
CAS 1424629-02-6C15H11ClFNO3S
N-{3-[3-(6-Chloropyridin-3-yl)prop-2-enoyl]phenyl}methanesulfonamide chemical structure, C15H13ClN2O3S, CAS 1445755-78-1
N-{3-[3-(6-Chloropyridin-3-yl)prop-2-enoyl]phenyl}methanesulfonamide
CAS 1445755-78-1C15H13ClN2O3S
(E)-3-(6-Chloro-3-pyridinyl)-1-(3-fluoro-4-methylsulfonylphenyl)prop-2-en-1-one chemical structure, C15H11ClFNO3S, CAS 1394802-87-9
(E)-3-(6-Chloro-3-pyridinyl)-1-(3-fluoro-4-methylsulfonylphenyl)prop-2-en-1-one
CAS 1394802-87-9C15H11ClFNO3S
3-(2,6-Dichloropyridin-3-yl)-1-(3,4-dimethoxyphenyl)prop-2-en-1-one chemical structure, C16H13Cl2NO3, CAS 1799275-14-1
3-(2,6-Dichloropyridin-3-yl)-1-(3,4-dimethoxyphenyl)prop-2-en-1-one
CAS 1799275-14-1C16H13Cl2NO3
2-{3-[3-(2-Chloropyridin-3-yl)prop-2-enoyl]phenoxy}acetic acid chemical structure, C16H12ClNO4, CAS 1607679-91-3
2-{3-[3-(2-Chloropyridin-3-yl)prop-2-enoyl]phenoxy}acetic acid
CAS 1607679-91-3C16H12ClNO4
2-{5-[3-(6-Chloropyridin-3-yl)prop-2-enoyl]-2-methoxyphenyl}acetic acid chemical structure, C17H14ClNO4, CAS 1608351-04-7
2-{5-[3-(6-Chloropyridin-3-yl)prop-2-enoyl]-2-methoxyphenyl}acetic acid
CAS 1608351-04-7C17H14ClNO4