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Murcko scaffold

Bicyclo(1.1.1)pentane scaffold

1,524 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
5
Chemicals
1,524
With full pages
209
Scaffold SMILES

C1C2CC1C2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Bicyclo(1.1.1)pentane page
Murcko scaffold C1C2CC1C2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 1,524 chemicals

Bicyclo(1.1.1)pentane chemical structure, C5H8, CAS 311-75-1
Bicyclo(1.1.1)pentane
CAS 311-75-1C5H8
Methyl bicyclo[1.1.1]pentane-1-carboxylate chemical structure, C7H10O2, CAS 106813-54-1
Methyl bicyclo[1.1.1]pentane-1-carboxylate
CAS 106813-54-1C7H10O2
(S)-(+)-Cbpg chemical structure, C8H11NO4, CAS 180465-02-5
(S)-(+)-Cbpg
CAS 180465-02-5C8H11NO4
1-Iodo-3-(trifluoromethyl)bicyclo[1.1.1]pentane chemical structure, C6H6F3I, CAS 119934-12-2
1-Iodo-3-(trifluoromethyl)bicyclo[1.1.1]pentane
CAS 119934-12-2C6H6F3I
1-Iodo-3-methoxybicyclo[1.1.1]pentane chemical structure, C6H9IO, CAS 136863-37-1
1-Iodo-3-methoxybicyclo[1.1.1]pentane
CAS 136863-37-1C6H9IO
{3-tert-Butylbicyclo[1.1.1]pentan-1-yl}methanol chemical structure, C10H18O, CAS 162374-89-2
{3-tert-Butylbicyclo[1.1.1]pentan-1-yl}methanol
CAS 162374-89-2C10H18O
Methyl 3-carbonofluoridoylbicyclo[1.1.1]pentane-1-carboxylate chemical structure, C8H9FO3, CAS 156329-85-0
Methyl 3-carbonofluoridoylbicyclo[1.1.1]pentane-1-carboxylate
CAS 156329-85-0C8H9FO3
3-Bromobicyclo[1.1.1]pentane-1-carboxylic acid chemical structure, C6H7BrO2, CAS 156329-70-3
3-Bromobicyclo[1.1.1]pentane-1-carboxylic acid
CAS 156329-70-3C6H7BrO2
(3-Bromo-1-bicyclo[1.1.1]pentanyl)methanol chemical structure, C6H9BrO, CAS 137741-16-3
(3-Bromo-1-bicyclo[1.1.1]pentanyl)methanol
CAS 137741-16-3C6H9BrO
3-[(R)-Amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-carboxylic acid chemical structure, C8H11NO4, CAS 180465-05-8
3-[(R)-Amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-carboxylic acid
CAS 180465-05-8C8H11NO4
{3-Bromobicyclo[1.1.1]pentan-1-yl}methyl acetate chemical structure, C8H11BrO2, CAS 137741-17-4
{3-Bromobicyclo[1.1.1]pentan-1-yl}methyl acetate
CAS 137741-17-4C8H11BrO2
3-tert-Butylbicyclo(1.1.1)pentane-1-carboxylic acid chemical structure, C10H16O2, CAS 132663-73-1
3-tert-Butylbicyclo(1.1.1)pentane-1-carboxylic acid
CAS 132663-73-1C10H16O2
3-Bromobicyclo[1.1.1]pentane-1-carbonitrile chemical structure, C6H6BrN, CAS 156329-61-2
3-Bromobicyclo[1.1.1]pentane-1-carbonitrile
CAS 156329-61-2C6H6BrN
1-Bromo-3-chlorobicyclo[1.1.1]pentane chemical structure, C5H6BrCl, CAS 155635-19-1
1-Bromo-3-chlorobicyclo[1.1.1]pentane
CAS 155635-19-1C5H6BrCl
Bicyclo[1.1.1]pentan-2-amine chemical structure, C5H9N, CAS 67947-39-1
Bicyclo[1.1.1]pentan-2-amine
CAS 67947-39-1C5H9N
Methyl 3-chlorobicyclo(1.1.1)pentane-1-carboxylate chemical structure, C7H9ClO2, CAS 156329-71-4
Methyl 3-chlorobicyclo(1.1.1)pentane-1-carboxylate
CAS 156329-71-4C7H9ClO2
1-(Bromomethyl)-3-tert-butylbicyclo[1.1.1]pentane chemical structure, C10H17Br, CAS 162374-92-7
1-(Bromomethyl)-3-tert-butylbicyclo[1.1.1]pentane
CAS 162374-92-7C10H17Br
Methyl 3-cyanobicyclo[1.1.1]pentane-1-carboxylate chemical structure, C8H9NO2, CAS 156329-62-3
Methyl 3-cyanobicyclo[1.1.1]pentane-1-carboxylate
CAS 156329-62-3C8H9NO2
1-Bromo-3-(chloromethyl)bicyclo[1.1.1]pentane chemical structure, C6H8BrCl, CAS 137741-18-5
1-Bromo-3-(chloromethyl)bicyclo[1.1.1]pentane
CAS 137741-18-5C6H8BrCl
3-Acetylbicyclo(1.1.1)pentane-1-carboxylic acid chemical structure, C8H10O3, CAS 156329-75-8
3-Acetylbicyclo(1.1.1)pentane-1-carboxylic acid
CAS 156329-75-8C8H10O3
1-Bromo-3-methylbicyclo[1.1.1]pentane chemical structure, C6H9Br, CAS 137741-15-2
1-Bromo-3-methylbicyclo[1.1.1]pentane
CAS 137741-15-2C6H9Br
Bicyclo[1.1.1]pentane-2-carboxylic acid chemical structure, C6H8O2, CAS 22287-40-7
Bicyclo[1.1.1]pentane-2-carboxylic acid
CAS 22287-40-7C6H8O2
3-Methylbicyclo[1.1.1]pentane-1-carboxylic acid chemical structure, C7H10O2, CAS 65862-01-3
3-Methylbicyclo[1.1.1]pentane-1-carboxylic acid
CAS 65862-01-3C7H10O2
3-Chlorobicyclo[1.1.1]pentane-1-carboxylic acid chemical structure, C6H7ClO2, CAS 156329-73-6
3-Chlorobicyclo[1.1.1]pentane-1-carboxylic acid
CAS 156329-73-6C6H7ClO2