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Murcko scaffold

4-(1,3-Benzodioxol-5-ylmethyl)-N-phenylpiperazine-1-carbothioamide scaffold

41 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
41
With full pages
7
Scaffold SMILES

S=C(Nc1ccccc1)N1CCN(Cc2ccc3c(c2)OCO3)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(1,3-Benzodioxol-5-ylmethyl)-N-phenylpiperazine-1-carbothioamide page
Murcko scaffold S=C(Nc1ccccc1)N1CCN(Cc2ccc3c(c2)OCO3)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 41 of 41 chemicals

4-(1,3-Benzodioxol-5-ylmethyl)-N-(4-methoxyphenyl)piperazine-1-carbothioamide chemical structure, C20H23N3O3S, CAS 364601-14-9
4-(1,3-Benzodioxol-5-ylmethyl)-N-(4-methoxyphenyl)piperazine-1-carbothioamide
CAS 364601-14-9C20H23N3O3S
4-(1,3-Benzodioxol-5-ylmethyl)-N-(3-chlorophenyl)piperazine-1-carbothioamide chemical structure, C19H20ClN3O2S, CAS 364337-83-7
4-(1,3-Benzodioxol-5-ylmethyl)-N-(3-chlorophenyl)piperazine-1-carbothioamide
CAS 364337-83-7C19H20ClN3O2S
Ethyl 4-({[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]carbonothioyl}amino)benzoate chemical structure, C22H25N3O4S, CAS 333758-53-5
Ethyl 4-({[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]carbonothioyl}amino)benzoate
CAS 333758-53-5C22H25N3O4S
4-(1,3-Benzodioxol-5-ylmethyl)-N-[4-(difluoromethoxy)phenyl]piperazine-1-carbothioamide chemical structure, C20H21F2N3O3S, CAS 473670-25-6
4-(1,3-Benzodioxol-5-ylmethyl)-N-[4-(difluoromethoxy)phenyl]piperazine-1-carbothioamide
CAS 473670-25-6C20H21F2N3O3S
Methyl [4-({[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]carbothioyl}amino)phenyl]acetate chemical structure, C22H25N3O4S, CAS 516457-92-4
Methyl [4-({[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]carbothioyl}amino)phenyl]acetate
CAS 516457-92-4C22H25N3O4S
4-(1,3-Benzodioxol-5-ylmethyl)-N-(2-methoxyphenyl)-1-piperazinecarbothioamide chemical structure, C20H23N3O3S, CAS 516457-93-5
4-(1,3-Benzodioxol-5-ylmethyl)-N-(2-methoxyphenyl)-1-piperazinecarbothioamide
CAS 516457-93-5C20H23N3O3S
4-(1,3-Benzodioxol-5-ylmethyl)-N-(4-chlorophenyl)piperazine-1-carbothioamide chemical structure, C19H20ClN3O2S, CAS 327093-51-6
4-(1,3-Benzodioxol-5-ylmethyl)-N-(4-chlorophenyl)piperazine-1-carbothioamide
CAS 327093-51-6C19H20ClN3O2S
N-(3-Acetylphenyl)-4-(1,3-benzodioxol-5-ylmethyl)piperazine-1-carbothioamide chemical structure, C21H23N3O3S, CAS 708222-12-2
N-(3-Acetylphenyl)-4-(1,3-benzodioxol-5-ylmethyl)piperazine-1-carbothioamide
CAS 708222-12-2C21H23N3O3S
4-(1,3-Benzodioxol-5-ylmethyl)-N-(3-methoxyphenyl)piperazine-1-carbothioamide chemical structure, C20H23N3O3S, CAS 431892-28-3
4-(1,3-Benzodioxol-5-ylmethyl)-N-(3-methoxyphenyl)piperazine-1-carbothioamide
CAS 431892-28-3C20H23N3O3S
4-(1,3-Benzodioxol-5-ylmethyl)-N-(2-methylphenyl)piperazine-1-carbothioamide chemical structure, C20H23N3O2S, CAS 431057-88-4
4-(1,3-Benzodioxol-5-ylmethyl)-N-(2-methylphenyl)piperazine-1-carbothioamide
CAS 431057-88-4C20H23N3O2S
4-(1,3-Benzodioxol-5-ylmethyl)-N-(3-chloro-2-methylphenyl)piperazine-1-carbothioamide chemical structure, C20H22ClN3O2S, CAS 433259-68-8
4-(1,3-Benzodioxol-5-ylmethyl)-N-(3-chloro-2-methylphenyl)piperazine-1-carbothioamide
CAS 433259-68-8C20H22ClN3O2S
4-(1,3-Benzodioxol-5-ylmethyl)-N-(2,4-dimethylphenyl)piperazine-1-carbothioamide chemical structure, C21H25N3O2S, CAS 433259-97-3
4-(1,3-Benzodioxol-5-ylmethyl)-N-(2,4-dimethylphenyl)piperazine-1-carbothioamide
CAS 433259-97-3C21H25N3O2S
4-(1,3-Benzodioxol-5-ylmethyl)-N-(3,5-dimethoxyphenyl)piperazine-1-carbothioamide chemical structure, C21H25N3O4S, CAS 433261-56-4
4-(1,3-Benzodioxol-5-ylmethyl)-N-(3,5-dimethoxyphenyl)piperazine-1-carbothioamide
CAS 433261-56-4C21H25N3O4S
4-(1,3-Benzodioxol-5-ylmethyl)-N-(3,5-dimethylphenyl)piperazine-1-carbothioamide chemical structure, C21H25N3O2S, CAS 433306-16-2
4-(1,3-Benzodioxol-5-ylmethyl)-N-(3,5-dimethylphenyl)piperazine-1-carbothioamide
CAS 433306-16-2C21H25N3O2S
4-(1,3-Benzodioxol-5-ylmethyl)-N-(4-chloro-2-methylphenyl)piperazine-1-carbothioamide chemical structure, C20H22ClN3O2S, CAS 433310-18-0
4-(1,3-Benzodioxol-5-ylmethyl)-N-(4-chloro-2-methylphenyl)piperazine-1-carbothioamide
CAS 433310-18-0C20H22ClN3O2S
4-(1,3-Benzodioxol-5-ylmethyl)-N-(2,5-dimethoxyphenyl)piperazine-1-carbothioamide chemical structure, C21H25N3O4S, CAS 433313-79-2
4-(1,3-Benzodioxol-5-ylmethyl)-N-(2,5-dimethoxyphenyl)piperazine-1-carbothioamide
CAS 433313-79-2C21H25N3O4S
4-(1,3-Benzodioxol-5-ylmethyl)-N-(4-bromophenyl)piperazine-1-carbothioamide chemical structure, C19H20BrN3O2S, CAS 431914-06-6
4-(1,3-Benzodioxol-5-ylmethyl)-N-(4-bromophenyl)piperazine-1-carbothioamide
CAS 431914-06-6C19H20BrN3O2S
4-(1,3-Benzodioxol-5-ylmethyl)-N-(3-fluorophenyl)piperazine-1-carbothioamide chemical structure, C19H20FN3O2S, CAS 431890-71-0
4-(1,3-Benzodioxol-5-ylmethyl)-N-(3-fluorophenyl)piperazine-1-carbothioamide
CAS 431890-71-0C19H20FN3O2S
4-(1,3-Benzodioxol-5-ylmethyl)-N-(2,4-dichlorophenyl)piperazine-1-carbothioamide chemical structure, C19H19Cl2N3O2S, CAS 6419-99-4
4-(1,3-Benzodioxol-5-ylmethyl)-N-(2,4-dichlorophenyl)piperazine-1-carbothioamide
CAS 6419-99-4C19H19Cl2N3O2S
4-(1,3-Benzodioxol-5-ylmethyl)-N-[3-(trifluoromethyl)phenyl]piperazine-1-carbothioamide chemical structure, C20H20F3N3O2S, CAS 428825-23-4
4-(1,3-Benzodioxol-5-ylmethyl)-N-[3-(trifluoromethyl)phenyl]piperazine-1-carbothioamide
CAS 428825-23-4C20H20F3N3O2S
4-(1,3-Benzodioxol-5-ylmethyl)-N-(3-methylphenyl)piperazine-1-carbothioamide chemical structure, C20H23N3O2S, CAS 6514-84-7
4-(1,3-Benzodioxol-5-ylmethyl)-N-(3-methylphenyl)piperazine-1-carbothioamide
CAS 6514-84-7C20H23N3O2S
4-(1,3-Benzodioxol-5-ylmethyl)-N-(2-chlorophenyl)piperazine-1-carbothioamide chemical structure, C19H20ClN3O2S, CAS 364749-64-4
4-(1,3-Benzodioxol-5-ylmethyl)-N-(2-chlorophenyl)piperazine-1-carbothioamide
CAS 364749-64-4C19H20ClN3O2S
4-(1,3-Benzodioxol-5-ylmethyl)-N-(4-chloro-2-fluorophenyl)piperazine-1-carbothioamide chemical structure, C19H19ClFN3O2S, CAS 327093-21-0
4-(1,3-Benzodioxol-5-ylmethyl)-N-(4-chloro-2-fluorophenyl)piperazine-1-carbothioamide
CAS 327093-21-0C19H19ClFN3O2S
4-(1,3-Benzodioxol-5-ylmethyl)-N-(2,5-dimethylphenyl)piperazine-1-carbothioamide chemical structure, C21H25N3O2S, CAS 433258-10-7
4-(1,3-Benzodioxol-5-ylmethyl)-N-(2,5-dimethylphenyl)piperazine-1-carbothioamide
CAS 433258-10-7C21H25N3O2S