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Murcko scaffold

Ring system with 5 rings and 26 atoms

77 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
26
Chemicals
77
With full pages
9
Scaffold SMILES

O=C(OCC1c2ccccc2-c2ccccc21)N1CCc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCC1c2ccccc2-c2ccccc21)N1CCc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 77 chemicals

(2S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2,3-dihydro-1H-indole-2-carboxylic acid chemical structure, C24H19NO4, CAS 198560-38-2
(2S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2,3-dihydro-1H-indole-2-carboxylic acid
CAS 198560-38-2C24H19NO4
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2,3-dihydro-1H-indole-2-carboxylic acid chemical structure, C24H19NO4, CAS 264273-07-6
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2,3-dihydro-1H-indole-2-carboxylic acid
CAS 264273-07-6C24H19NO4
(2R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2,3-dihydro-1H-indole-2-carboxylic acid chemical structure, C24H19NO4, CAS 2243501-23-5
(2R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2,3-dihydro-1H-indole-2-carboxylic acid
CAS 2243501-23-5C24H19NO4
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2,3-dihydro-1H-indole-5-carboxylic acid chemical structure, C24H19NO4, CAS 1339770-58-9
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2,3-dihydro-1H-indole-5-carboxylic acid
CAS 1339770-58-9C24H19NO4
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2,3-dihydro-1H-indol-3-yl)acetic acid chemical structure, C25H21NO4, CAS 1488022-26-9
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2,3-dihydro-1H-indol-3-yl)acetic acid
CAS 1488022-26-9C25H21NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2,3-dihydro-1H-indole-3-carboxylic acid chemical structure, C24H19NO4, CAS 1520767-28-5
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2,3-dihydro-1H-indole-3-carboxylic acid
CAS 1520767-28-5C24H19NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2,3-dihydro-1H-indole-6-carboxylic acid chemical structure, C24H19NO4, CAS 1566149-63-0
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2,3-dihydro-1H-indole-6-carboxylic acid
CAS 1566149-63-0C24H19NO4
2-(5-Bromo-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2,3-dihydro-1H-indol-3-yl)acetic acid chemical structure, C25H20BrNO4, CAS 2138213-22-4
2-(5-Bromo-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2,3-dihydro-1H-indol-3-yl)acetic acid
CAS 2138213-22-4C25H20BrNO4
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2,3-dihydro-1H-indol-6-yl)acetic acid chemical structure, C25H21NO4, CAS 2138021-20-0
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2,3-dihydro-1H-indol-6-yl)acetic acid
CAS 2138021-20-0C25H21NO4
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2,3-dihydro-1H-indole-4-carboxylic acid chemical structure, C24H19NO4, CAS 2219418-90-1
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-2,3-dihydro-1H-indole-4-carboxylic acid
CAS 2219418-90-1C24H19NO4
1-(9H-Fluoren-9-ylmethoxycarbonyl)-6-fluoro-2,3-dihydroindole-2-carboxylic acid chemical structure, C24H18FNO4, CAS 2386752-38-9
1-(9H-Fluoren-9-ylmethoxycarbonyl)-6-fluoro-2,3-dihydroindole-2-carboxylic acid
CAS 2386752-38-9C24H18FNO4
6-Bromo-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2,3-dihydro-1H-indole-4-carboxylic acid chemical structure, C24H18BrNO4, CAS 2639426-13-2
6-Bromo-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2,3-dihydro-1H-indole-4-carboxylic acid
CAS 2639426-13-2C24H18BrNO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3,3-dimethyl-2,3-dihydro-1H-indole-5-carboxylic acid chemical structure, C26H23NO4, CAS 2287272-11-9
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3,3-dimethyl-2,3-dihydro-1H-indole-5-carboxylic acid
CAS 2287272-11-9C26H23NO4
(2S)-5-Bromo-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2,3-dihydro-1H-indole-2-carboxylic acid chemical structure, C24H18BrNO4, CAS 1251904-22-9
(2S)-5-Bromo-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2,3-dihydro-1H-indole-2-carboxylic acid
CAS 1251904-22-9C24H18BrNO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-methoxy-2,3-dihydro-1H-indole-2-carboxylic acid chemical structure, C25H21NO5, CAS 2137506-44-4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-methoxy-2,3-dihydro-1H-indole-2-carboxylic acid
CAS 2137506-44-4C25H21NO5
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6-methyl-2,3-dihydro-1H-indole-3-carboxylic acid chemical structure, C25H21NO4, CAS 2137831-77-5
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6-methyl-2,3-dihydro-1H-indole-3-carboxylic acid
CAS 2137831-77-5C25H21NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(propan-2-yloxy)-2,3-dihydro-1H-indole-2-carboxylic acid chemical structure, C27H25NO5, CAS 2137451-62-6
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(propan-2-yloxy)-2,3-dihydro-1H-indole-2-carboxylic acid
CAS 2137451-62-6C27H25NO5
3-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2,3-dihydro-1H-indol-3-yl)propanoic acid chemical structure, C26H23NO4, CAS 2138371-93-2
3-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2,3-dihydro-1H-indol-3-yl)propanoic acid
CAS 2138371-93-2C26H23NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-methyl-2,3-dihydro-1H-indole-2-carboxylic acid chemical structure, C25H21NO4, CAS 2137472-99-0
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-methyl-2,3-dihydro-1H-indole-2-carboxylic acid
CAS 2137472-99-0C25H21NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-hydroxy-2,3-dihydro-1H-indole-2-carboxylic acid chemical structure, C24H19NO5, CAS 2137447-91-5
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-hydroxy-2,3-dihydro-1H-indole-2-carboxylic acid
CAS 2137447-91-5C24H19NO5
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6-hydroxy-2,3-dihydro-1H-indole-2-carboxylic acid chemical structure, C24H19NO5, CAS 2137447-94-8
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-6-hydroxy-2,3-dihydro-1H-indole-2-carboxylic acid
CAS 2137447-94-8C24H19NO5
6-Chloro-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2,3-dihydro-1H-indole-5-carboxylic acid chemical structure, C24H18ClNO4, CAS 2243514-71-6
6-Chloro-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2,3-dihydro-1H-indole-5-carboxylic acid
CAS 2243514-71-6C24H18ClNO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3,3-dimethyl-2,3-dihydro-1H-indole-2-carboxylic acid chemical structure, C26H23NO4, CAS 2243503-33-3
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3,3-dimethyl-2,3-dihydro-1H-indole-2-carboxylic acid
CAS 2243503-33-3C26H23NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-methoxy-2,3-dihydro-1H-indole-3-carboxylic acid chemical structure, C25H21NO5, CAS 2138265-50-4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-methoxy-2,3-dihydro-1H-indole-3-carboxylic acid
CAS 2138265-50-4C25H21NO5