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Murcko scaffold

Ring system with 4 rings and 22 atoms

1,530 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
1,530
With full pages
12
Scaffold SMILES

O=C(NCC1CC1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCC1CC1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 1,530 chemicals

(2S)-2-Cyclopropyl-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)acetic acid chemical structure, C20H19NO4, CAS 1212257-18-5
(2S)-2-Cyclopropyl-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)acetic acid
CAS 1212257-18-5C20H19NO4
Fmoc-D-cyclopropylglycine chemical structure, C20H19NO4, CAS 923012-40-2
Fmoc-D-cyclopropylglycine
CAS 923012-40-2C20H19NO4
3-Cyclopropyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C21H21NO4, CAS 683217-51-8
3-Cyclopropyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 683217-51-8C21H21NO4
1-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclopropane-1-carboxylic acid chemical structure, C20H19NO4, CAS 1263045-62-0
1-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclopropane-1-carboxylic acid
CAS 1263045-62-0C20H19NO4
2-Cyclopropyl-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)acetic acid chemical structure, C20H19NO4, CAS 1332765-55-5
2-Cyclopropyl-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)acetic acid
CAS 1332765-55-5C20H19NO4
2-Cyclopropyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C21H21NO4, CAS 1340154-82-6
2-Cyclopropyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 1340154-82-6C21H21NO4
2-[(Cyclopropylmethyl)({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]acetic acid chemical structure, C21H21NO4, CAS 1341306-32-8
2-[(Cyclopropylmethyl)({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]acetic acid
CAS 1341306-32-8C21H21NO4
(R)-3-Cyclopropyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid chemical structure, C21H21NO4, CAS 1260589-74-9
(R)-3-Cyclopropyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid
CAS 1260589-74-9C21H21NO4
(S)-3-Cyclopropyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid chemical structure, C21H21NO4, CAS 1260605-12-6
(S)-3-Cyclopropyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid
CAS 1260605-12-6C21H21NO4
(9H-Fluoren-9-yl)methyl ((2,2-dichlorocyclopropyl)methyl)carbamate chemical structure, C19H17Cl2NO2, CAS 1528563-72-5
(9H-Fluoren-9-yl)methyl ((2,2-dichlorocyclopropyl)methyl)carbamate
CAS 1528563-72-5C19H17Cl2NO2
(9H-Fluoren-9-yl)methyl N-[(1R)-1-cyclopropyl-3-hydroxypropyl]carbamate chemical structure, C21H23NO3, CAS 2763895-43-6
(9H-Fluoren-9-yl)methyl N-[(1R)-1-cyclopropyl-3-hydroxypropyl]carbamate
CAS 2763895-43-6C21H23NO3
2-Cyclopropyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)propanoic acid chemical structure, C22H23NO4, CAS 1696362-37-4
2-Cyclopropyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)propanoic acid
CAS 1696362-37-4C22H23NO4
2-Cyclopropyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)acetic acid chemical structure, C21H21NO4, CAS 1702784-66-4
2-Cyclopropyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)acetic acid
CAS 1702784-66-4C21H21NO4
2-Cyclopropyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid chemical structure, C22H23NO4, CAS 1698797-51-1
2-Cyclopropyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid
CAS 1698797-51-1C22H23NO4
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-(1-methylcyclopropyl)propanoic acid chemical structure, C22H23NO4, CAS 1702969-33-2
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-(1-methylcyclopropyl)propanoic acid
CAS 1702969-33-2C22H23NO4
(9H-Fluoren-9-yl)methyl N-{[1-(2-hydroxyethyl)cyclopropyl]methyl}carbamate chemical structure, C21H23NO3, CAS 1601044-11-4
(9H-Fluoren-9-yl)methyl N-{[1-(2-hydroxyethyl)cyclopropyl]methyl}carbamate
CAS 1601044-11-4C21H23NO3
(9H-Fluoren-9-yl)methyl N-{[1-(hydroxymethyl)cyclopropyl]methyl}carbamate chemical structure, C20H21NO3, CAS 1546764-23-1
(9H-Fluoren-9-yl)methyl N-{[1-(hydroxymethyl)cyclopropyl]methyl}carbamate
CAS 1546764-23-1C20H21NO3
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-[2-(trifluoromethyl)cyclopropyl]acetic acid chemical structure, C21H18F3NO4, CAS 1922859-03-7
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-[2-(trifluoromethyl)cyclopropyl]acetic acid
CAS 1922859-03-7C21H18F3NO4
2-{1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclopropyl}acetic acid chemical structure, C21H21NO4, CAS 2094859-65-9
2-{1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclopropyl}acetic acid
CAS 2094859-65-9C21H21NO4
(9H-Fluoren-9-yl)methyl N-(1-cyclopropyl-3-hydroxypropyl)carbamate chemical structure, C21H23NO3, CAS 683220-80-6
(9H-Fluoren-9-yl)methyl N-(1-cyclopropyl-3-hydroxypropyl)carbamate
CAS 683220-80-6C21H23NO3
Fmoc-Ala(alpha-cyclopropyl)-OH chemical structure, C21H21NO4, CAS 1926163-87-2
Fmoc-Ala(alpha-cyclopropyl)-OH
CAS 1926163-87-2C21H21NO4
Fmoc-D-Ala(alpha-cyclopropyl)-OH H2O chemical structure, C21H21NO4, CAS 1926163-86-1
Fmoc-D-Ala(alpha-cyclopropyl)-OH H2O
CAS 1926163-86-1C21H21NO4
(1S,2S)-1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-2-methanesulfonylcyclopropane-1-carboxylic acid chemical structure, C21H21NO6S, CAS 2137098-15-6
(1S,2S)-1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-2-methanesulfonylcyclopropane-1-carboxylic acid
CAS 2137098-15-6C21H21NO6S
rac-(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclopropane-1-carboxylic acid chemical structure, C20H19NO4, CAS 2088112-39-2
rac-(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclopropane-1-carboxylic acid
CAS 2088112-39-2C20H19NO4