CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 20 atoms

163 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
163
With full pages
43
Scaffold SMILES

O=c1ccn(C2CC2)c2cc(N3CCNCC3)ccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccn(C2CC2)c2cc(N3CCNCC3)ccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 163 chemicals

Ciprofloxacin chemical structure, C17H18FN3O3, CAS 85721-33-1
Ciprofloxacin
CAS 85721-33-1C17H18FN3O3
5-Amino-1-cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid chemical structure, C19H22F2N4O3, CAS 111542-93-9
5-Amino-1-cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS 111542-93-9C19H22F2N4O3
Gatifloxacin chemical structure, C19H22FN3O4, CAS 112811-59-3
Gatifloxacin
CAS 112811-59-3C19H22FN3O4
Sparfloxacin chemical structure, C19H22F2N4O3, CAS 110871-86-8
Sparfloxacin
CAS 110871-86-8C19H22F2N4O3
Orbifloxacin chemical structure, C19H20F3N3O3, CAS 113617-63-3
Orbifloxacin
CAS 113617-63-3C19H20F3N3O3
Ciprofloxacin hydrochloride monohydrate chemical structure, C17H21ClFN3O4, CAS 86393-32-0
Ciprofloxacin hydrochloride monohydrate
CAS 86393-32-0C17H21ClFN3O4
Ciprofloxacin hydrochloride anhydrous chemical structure, C17H19ClFN3O3, CAS 93107-08-5
Ciprofloxacin hydrochloride anhydrous
CAS 93107-08-5C17H19ClFN3O3
Enrofloxacin chemical structure, C19H22FN3O3, CAS 93106-60-6
Enrofloxacin
CAS 93106-60-6C19H22FN3O3
Grepafloxacin chemical structure, C19H22FN3O3, CAS 119914-60-2
Grepafloxacin
CAS 119914-60-2C19H22FN3O3
8-Fluorociprofloxacin chemical structure, C17H17F2N3O3, CAS 94242-53-2
8-Fluorociprofloxacin
CAS 94242-53-2C17H17F2N3O3
Sulfociprofloxacin chemical structure, C17H18FN3O6S, CAS 105093-21-8
Sulfociprofloxacin
CAS 105093-21-8C17H18FN3O6S
5-Amino-1-cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxoquinoline-3-carboxylic acid chemical structure, C19H23FN4O3, CAS 123016-40-0
5-Amino-1-cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxoquinoline-3-carboxylic acid
CAS 123016-40-0C19H23FN4O3
1-Cyclopropyl-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid chemical structure, C18H20FN3O3, CAS 93107-32-5
1-Cyclopropyl-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
CAS 93107-32-5C18H20FN3O3
Cadrofloxacin chemical structure, C19H20F3N3O4, CAS 153808-85-6
Cadrofloxacin
CAS 153808-85-6C19H20F3N3O4
1-Cyclopropyl-7-(4-ethyl-piperazin-1-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid chemical structure, C20H24FN3O4, CAS 182868-63-9
1-Cyclopropyl-7-(4-ethyl-piperazin-1-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid
CAS 182868-63-9C20H24FN3O4
8-Bromo-1-cyclopropyl-6-fluoro-7-(3-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid chemical structure, C18H19BrFN3O3, CAS 182868-35-5
8-Bromo-1-cyclopropyl-6-fluoro-7-(3-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid
CAS 182868-35-5C18H19BrFN3O3
1-Cyclopropyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid chemical structure, C18H19F2N3O3, CAS 103460-89-5
1-Cyclopropyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS 103460-89-5C18H19F2N3O3
3-Quinolinecarboxylic acid, 1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo- chemical structure, C19H21F2N3O3, CAS 103460-90-8
3-Quinolinecarboxylic acid, 1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo-
CAS 103460-90-8C19H21F2N3O3
3-Quinolinecarboxylic acid, 8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)- chemical structure, C17H17ClFN3O3, CAS 99696-22-7
3-Quinolinecarboxylic acid, 8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-
CAS 99696-22-7C17H17ClFN3O3
3-Quinolinecarboxylic acid, 1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo- chemical structure, C20H24FN3O4, CAS 183254-47-9
3-Quinolinecarboxylic acid, 1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-
CAS 183254-47-9C20H24FN3O4
3-Quinolinecarboxylic acid, 1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo- chemical structure, C19H22FN3O3, CAS 93107-34-7
3-Quinolinecarboxylic acid, 1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-
CAS 93107-34-7C19H22FN3O3
3-Quinolinecarboxylic acid, 1-cyclopropyl-7-(3-ethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo- chemical structure, C19H21F2N3O3, CAS 183254-49-1
3-Quinolinecarboxylic acid, 1-cyclopropyl-7-(3-ethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo-
CAS 183254-49-1C19H21F2N3O3
3-Quinolinecarboxylic acid, 1-cyclopropyl-7-(3-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo- chemical structure, C19H22FN3O3, CAS 93107-33-6
3-Quinolinecarboxylic acid, 1-cyclopropyl-7-(3-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-
CAS 93107-33-6C19H22FN3O3
3-Quinolinecarboxylic acid, 8-chloro-1-cyclopropyl-7-(3-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo- chemical structure, C19H21ClFN3O3, CAS 183135-59-3
3-Quinolinecarboxylic acid, 8-chloro-1-cyclopropyl-7-(3-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-
CAS 183135-59-3C19H21ClFN3O3