Murcko scaffold
3,4-Dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane] scaffold
61 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 12
- Chemicals
- 61
- With full pages
- 3
Scaffold SMILES
c1ccc2c(c1)NCC1(CC1)O2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 61 chemicals
![3,4-Dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane] chemical structure, C10H11NO, CAS 1784783-18-1](/s/NFQAUVGOGYMJGP-UHFFFAOYSA-N.svg)
3,4-Dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]
CAS 1784783-18-1C10H11NO
![6-Bromo-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane] chemical structure, C10H10BrNO, CAS 1291094-46-6](/s/MEKWQPBFYRGZDS-UHFFFAOYSA-N.svg)
6-Bromo-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane]
CAS 1291094-46-6C10H10BrNO
![6-Methyl-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane] chemical structure, C11H13NO, CAS 1894940-38-5](/s/IRTZGQKHHCNUOJ-UHFFFAOYSA-N.svg)
6-Methyl-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane]
CAS 1894940-38-5C11H13NO
![8-Methyl-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane] chemical structure, C11H13NO, CAS 1893198-88-3](/s/AEESYJRHGARGEN-UHFFFAOYSA-N.svg)
8-Methyl-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane]
CAS 1893198-88-3C11H13NO
![8-Fluoro-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane] chemical structure, C10H10FNO, CAS 1890392-62-7](/s/UWZQTLSYDQHCEO-UHFFFAOYSA-N.svg)
8-Fluoro-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane]
CAS 1890392-62-7C10H10FNO
![8-Bromo-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane] chemical structure, C10H10BrNO, CAS 1893463-18-7](/s/XABIAXDUDUCYMM-UHFFFAOYSA-N.svg)
8-Bromo-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]
CAS 1893463-18-7C10H10BrNO
![5-Methyl-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane] chemical structure, C11H13NO, CAS 1897852-62-8](/s/WPFGVSIQSJLRDN-UHFFFAOYSA-N.svg)
5-Methyl-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane]
CAS 1897852-62-8C11H13NO
![5-Fluoro-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane] chemical structure, C10H10FNO, CAS 1894940-23-8](/s/WYXJOAKPIJDCCY-UHFFFAOYSA-N.svg)
5-Fluoro-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]
CAS 1894940-23-8C10H10FNO
![5-Chloro-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane] chemical structure, C10H10ClNO, CAS 1896588-76-3](/s/KEGXEQKUZFDHDT-UHFFFAOYSA-N.svg)
5-Chloro-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane]
CAS 1896588-76-3C10H10ClNO
![5-Bromo-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane] chemical structure, C10H10BrNO, CAS 1893136-56-5](/s/ZGIDKAMZPMUNKT-UHFFFAOYSA-N.svg)
5-Bromo-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane]
CAS 1893136-56-5C10H10BrNO
![5-Methoxy-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane] chemical structure, C11H13NO2, CAS 1897809-90-3](/s/YZEZHBXGDKBAMM-UHFFFAOYSA-N.svg)
5-Methoxy-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane]
CAS 1897809-90-3C11H13NO2
![6-Fluoro-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane] chemical structure, C10H10FNO, CAS 1897525-88-0](/s/QVVCQQICCHQPJX-UHFFFAOYSA-N.svg)
6-Fluoro-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane]
CAS 1897525-88-0C10H10FNO
![6-Chloro-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane] chemical structure, C10H10ClNO, CAS 1888884-90-9](/s/YGROUAILMITWMW-UHFFFAOYSA-N.svg)
6-Chloro-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]
CAS 1888884-90-9C10H10ClNO
![6-Methoxy-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane] chemical structure, C11H13NO2, CAS 1891194-71-0](/s/HNLUIZNGSOMYMZ-UHFFFAOYSA-N.svg)
6-Methoxy-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane]
CAS 1891194-71-0C11H13NO2
![7-Methyl-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane] chemical structure, C11H13NO, CAS 1896548-70-1](/s/MCTGYRXJYOJJQY-UHFFFAOYSA-N.svg)
7-Methyl-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane]
CAS 1896548-70-1C11H13NO
![7-Fluoro-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane] chemical structure, C10H10FNO, CAS 1893225-77-8](/s/MQKVTOWCOJAPSE-UHFFFAOYSA-N.svg)
7-Fluoro-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane]
CAS 1893225-77-8C10H10FNO
![7-Chloro-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane] chemical structure, C10H10ClNO, CAS 1893192-57-8](/s/PKXXEMYWJDFEOQ-UHFFFAOYSA-N.svg)
7-Chloro-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]
CAS 1893192-57-8C10H10ClNO
![7-Bromo-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane] chemical structure, C10H10BrNO, CAS 1891194-91-4](/s/IJXYSJNLEFSFRD-UHFFFAOYSA-N.svg)
7-Bromo-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]
CAS 1891194-91-4C10H10BrNO
![7-Methoxy-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane] chemical structure, C11H13NO2, CAS 1896007-10-5](/s/XVAYIFYWPVJOJH-UHFFFAOYSA-N.svg)
7-Methoxy-3,4-dihydrospiro[benzo[b][1,4]oxazine-2,1'-cyclopropane]
CAS 1896007-10-5C11H13NO2
![3,4-Dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane] hydrochloride chemical structure, C10H12ClNO, CAS 2138280-47-2](/s/XOYVYXXATNTVBB-UHFFFAOYSA-N.svg)
3,4-Dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane] hydrochloride
CAS 2138280-47-2C10H12ClNO
![Methyl 3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-6-carboxylate chemical structure, C12H13NO3, CAS 1824190-01-3](/s/BAMUFTFPQBXURM-UHFFFAOYSA-N.svg)
Methyl 3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-6-carboxylate
CAS 1824190-01-3C12H13NO3
![7-Bromo-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane] hydrochloride chemical structure, C10H11BrClNO, CAS 2247102-81-2](/s/ZJCKTSAKMZWTQG-UHFFFAOYSA-N.svg)
7-Bromo-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane] hydrochloride
CAS 2247102-81-2C10H11BrClNO
![3,4-Dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-8-carboxylic acid hydrochloride chemical structure, C11H12ClNO3, CAS 2375271-11-5](/s/LJNWONNNSCHCIC-UHFFFAOYSA-N.svg)
3,4-Dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-8-carboxylic acid hydrochloride
CAS 2375271-11-5C11H12ClNO3
![3,4-Dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-8-carboxylic acid chemical structure, C11H11NO3, CAS 2138001-77-9](/s/XDMLRLIMTLGQOY-UHFFFAOYSA-N.svg)
3,4-Dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-8-carboxylic acid
CAS 2138001-77-9C11H11NO3
- Methyl 3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-8-carboxylate2375270-22-5C12H13NO3
- 2-Chloro-1-spiro[3H-1,4-benzoxazine-2,1'-cyclopropane]-4-ylpropan-1-one2411295-72-0C13H14ClNO2
- tert-Butyl 3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-4-carboxylate2137668-06-3C15H19NO3
- tert-Butyl 7-bromo-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-4-carboxylate2138220-87-6C15H18BrNO3
- 3,4-Dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-7-carboxylic acid2138001-48-4C11H11NO3
- 4-[(tert-Butoxy)carbonyl]-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-6-carboxylic acid2138001-51-9C16H19NO5
- 4-[(tert-Butoxy)carbonyl]-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-8-carboxylic acid2138356-96-2C16H19NO5
- {3,4-Dihydrospiro[1,4-benzoxazine-2,1'-cyclopropan]-6-yl}methanol2138531-27-6C11H13NO2
- {3,4-Dihydrospiro[1,4-benzoxazine-2,1'-cyclopropan]-8-yl}methanol2137885-84-6C11H13NO2
- tert-Butyl 6-(hydroxymethyl)-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-4-carboxylate2138000-37-8C16H21NO4
- tert-Butyl 7-amino-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-4-carboxylate2137885-93-7C15H20N2O3
- tert-Butyl N-{3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropan]-7-yl}carbamate2137668-34-7C15H20N2O3
- tert-Butyl 7-fluoro-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-4-carboxylate2138282-92-3C15H18FNO3
- tert-Butyl 5-fluoro-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-4-carboxylate2137819-81-7C15H18FNO3
- tert-Butyl 6-bromo-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-4-carboxylate2137602-84-5C15H18BrNO3
- tert-Butyl 6-chloro-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-4-carboxylate2138001-62-2C15H18ClNO3
- tert-Butyl 8-bromo-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-4-carboxylate2138001-71-3C15H18BrNO3
- tert-Butyl N-{3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropan]-6-yl}carbamate2137616-23-8C15H20N2O3
- tert-Butyl N-{3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropan]-8-yl}carbamate2137616-28-3C15H20N2O3
- tert-Butyl 7-chloro-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-4-carboxylate2137702-09-9C15H18ClNO3
- 3,4-Dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-6-carboxylic acid2138012-75-4C11H11NO3
- tert-Butyl 7-(hydroxymethyl)-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-4-carboxylate2138531-31-2C16H21NO4
- tert-Butyl 6-amino-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-4-carboxylate2138160-18-4C15H20N2O3
- 4-[(tert-Butoxy)carbonyl]-3,4-dihydrospiro[1,4-benzoxazine-2,1'-cyclopropane]-7-carboxylic acid2137588-24-8C16H19NO5
Related scaffolds
Same ring framework with different atoms or bond orders
