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Murcko scaffold

Ring system with 4 rings and 21 atoms

427 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
427
With full pages
4
Scaffold SMILES

O=C(NC1CC1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC1CC1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 427 chemicals

1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopropanecarboxylic acid chemical structure, C19H17NO4, CAS 126705-22-4
1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclopropanecarboxylic acid
CAS 126705-22-4C19H17NO4
1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2,2-dimethylcyclopropane-1-carboxylic acid chemical structure, C21H21NO4, CAS 885951-75-7
1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2,2-dimethylcyclopropane-1-carboxylic acid
CAS 885951-75-7C21H21NO4
(9H-Fluoren-9-yl)methyl 1-formylcyclopropylcarbamate chemical structure, C19H17NO3, CAS 639859-13-5
(9H-Fluoren-9-yl)methyl 1-formylcyclopropylcarbamate
CAS 639859-13-5C19H17NO3
(9H-Fluoren-9-yl)methyl N-[1-(hydroxymethyl)cyclopropyl]carbamate chemical structure, C19H19NO3, CAS 639859-11-3
(9H-Fluoren-9-yl)methyl N-[1-(hydroxymethyl)cyclopropyl]carbamate
CAS 639859-11-3C19H19NO3
(2S)-2-[Cyclopropyl(9H-fluoren-9-ylmethoxycarbonyl)amino]propanoic acid chemical structure, C21H21NO4, CAS 1821827-07-9
(2S)-2-[Cyclopropyl(9H-fluoren-9-ylmethoxycarbonyl)amino]propanoic acid
CAS 1821827-07-9C21H21NO4
(9H-Fluoren-9-yl)methyl 1-(methoxycarbonyl)-cyclopropylcarbamate chemical structure, C20H19NO4, CAS 914223-82-8
(9H-Fluoren-9-yl)methyl 1-(methoxycarbonyl)-cyclopropylcarbamate
CAS 914223-82-8C20H19NO4
2-{Cyclopropyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid chemical structure, C20H19NO4, CAS 1342767-08-1
2-{Cyclopropyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid
CAS 1342767-08-1C20H19NO4
N-Fmoc-N-cyclopropyl-L-alanine chemical structure, C21H21NO4
N-Fmoc-N-cyclopropyl-L-alanine
C21H21NO4
(1R,2S)-1-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-vinylcyclopropanecarboxylic acid chemical structure, C21H19NO4, CAS 925240-91-1
(1R,2S)-1-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-vinylcyclopropanecarboxylic acid
CAS 925240-91-1C21H19NO4
(9H-Fluoren-9-yl)methyl N-cyclopropyl-N-(2-hydroxyethyl)carbamate chemical structure, C20H21NO3, CAS 1342068-42-1
(9H-Fluoren-9-yl)methyl N-cyclopropyl-N-(2-hydroxyethyl)carbamate
CAS 1342068-42-1C20H21NO3
3-(Cyclopropyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino)propanoic acid chemical structure, C21H21NO4, CAS 1343275-93-3
3-(Cyclopropyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino)propanoic acid
CAS 1343275-93-3C21H21NO4
(1R,2S)-1-(((9H-Fluoren-9-yl)methoxy)carbonylamino)-2-methylcyclopropanecarboxylic acid chemical structure, C20H19NO4, CAS 1380327-46-7
(1R,2S)-1-(((9H-Fluoren-9-yl)methoxy)carbonylamino)-2-methylcyclopropanecarboxylic acid
CAS 1380327-46-7C20H19NO4
1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylcyclopropane-1-carboxylic acid chemical structure, C20H19NO4, CAS 2997361-38-1
1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylcyclopropane-1-carboxylic acid
CAS 2997361-38-1C20H19NO4
3-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopropyl]prop-2-ynoic acid chemical structure, C21H17NO4, CAS 1268810-12-3
3-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopropyl]prop-2-ynoic acid
CAS 1268810-12-3C21H17NO4
1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}(methyl)amino)cyclopropane-1-carboxylic acid chemical structure, C20H19NO4, CAS 1702888-95-6
1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}(methyl)amino)cyclopropane-1-carboxylic acid
CAS 1702888-95-6C20H19NO4
1-((((9H-Fluoren-9-yl)methoxy)carbonyl)(ethyl)amino)cyclopropane-1-carboxylic acid chemical structure, C21H21NO4, CAS 1698188-75-8
1-((((9H-Fluoren-9-yl)methoxy)carbonyl)(ethyl)amino)cyclopropane-1-carboxylic acid
CAS 1698188-75-8C21H21NO4
1-[Fmoc-(propyl)amino]cyclopropanecarboxylic Acid chemical structure, C22H23NO4, CAS 1696590-51-8
1-[Fmoc-(propyl)amino]cyclopropanecarboxylic Acid
CAS 1696590-51-8C22H23NO4
1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}(propan-2-yl)amino)cyclopropane-1-carboxylic acid chemical structure, C22H23NO4, CAS 1698640-18-4
1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}(propan-2-yl)amino)cyclopropane-1-carboxylic acid
CAS 1698640-18-4C22H23NO4
2-[Cyclopropyl({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]butanoic acid chemical structure, C22H23NO4, CAS 1699223-98-7
2-[Cyclopropyl({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]butanoic acid
CAS 1699223-98-7C22H23NO4
2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopropyl]acetic acid chemical structure, C20H19NO4, CAS 1219953-64-6
2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopropyl]acetic acid
CAS 1219953-64-6C20H19NO4
rac-(1R,2R)-1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-(trifluoromethyl)cyclopropane-1-carboxylicacid chemical structure, C20H16F3NO4, CAS 1992961-54-2
rac-(1R,2R)-1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-(trifluoromethyl)cyclopropane-1-carboxylicacid
CAS 1992961-54-2C20H16F3NO4
Fmoc-(2r,3s)-2,3-methanoleucine chemical structure, C22H23NO4, CAS 1416059-90-9
Fmoc-(2r,3s)-2,3-methanoleucine
CAS 1416059-90-9C22H23NO4
Sodium 1-[(9H-Fluoren-9-ylmethoxy)carbonylamino]cyclopropanecarboxylate chemical structure, C19H16NNaO4, CAS 2701344-50-3
Sodium 1-[(9H-Fluoren-9-ylmethoxy)carbonylamino]cyclopropanecarboxylate
CAS 2701344-50-3C19H16NNaO4
2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopropyl]propanoic acid chemical structure, C21H21NO4, CAS 2138353-62-3
2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopropyl]propanoic acid
CAS 2138353-62-3C21H21NO4