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Murcko scaffold

Ring system with 4 rings and 20 atoms

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
12
With full pages
3
Scaffold SMILES

O=C1C(=Nc2ccccc2)c2cccc3c2N1CCC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C(=Nc2ccccc2)c2cccc3c2N1CCC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

(1E)-1-{[4-(Propan-2-yl)phenyl]imino}-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one chemical structure, C20H20N2O, CAS 774559-89-6
(1E)-1-{[4-(Propan-2-yl)phenyl]imino}-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one
CAS 774559-89-6C20H20N2O
(1E)-1-[(4-Methoxyphenyl)imino]-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one chemical structure, C18H16N2O2, CAS 774559-90-9
(1E)-1-[(4-Methoxyphenyl)imino]-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one
CAS 774559-90-9C18H16N2O2
Dimethyl 5-{[(1E)-2-oxo-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1(2H)-ylidene]amino}benzene-1,3-dicarboxylate chemical structure, C21H18N2O5, CAS 774560-00-8
Dimethyl 5-{[(1E)-2-oxo-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1(2H)-ylidene]amino}benzene-1,3-dicarboxylate
CAS 774560-00-8C21H18N2O5
(1E)-1-[(3-Methoxyphenyl)imino]-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one chemical structure, C18H16N2O2, CAS 774559-92-1
(1E)-1-[(3-Methoxyphenyl)imino]-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one
CAS 774559-92-1C18H16N2O2
(1E)-1-[(3,4-Dichlorophenyl)imino]-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one chemical structure, C17H12Cl2N2O, CAS 774559-94-3
(1E)-1-[(3,4-Dichlorophenyl)imino]-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one
CAS 774559-94-3C17H12Cl2N2O
(1E)-1-[(3,5-Dimethoxyphenyl)imino]-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one chemical structure, C19H18N2O3, CAS 774559-99-8
(1E)-1-[(3,5-Dimethoxyphenyl)imino]-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one
CAS 774559-99-8C19H18N2O3
(1E)-1-[(3,5-Dichlorophenyl)imino]-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one chemical structure, C17H12Cl2N2O, CAS 774559-98-7
(1E)-1-[(3,5-Dichlorophenyl)imino]-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one
CAS 774559-98-7C17H12Cl2N2O
(1E)-1-[(4-Fluorophenyl)imino]-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one chemical structure, C17H13FN2O, CAS 774559-88-5
(1E)-1-[(4-Fluorophenyl)imino]-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one
CAS 774559-88-5C17H13FN2O
(1Z)-4,4,6,8-Tetramethyl-1-[(4-methylphenyl)imino]-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one chemical structure, C22H24N2O, CAS 524047-04-9
(1Z)-4,4,6,8-Tetramethyl-1-[(4-methylphenyl)imino]-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one
CAS 524047-04-9C22H24N2O
(1Z)-1-[(4-Methoxyphenyl)imino]-4,4,6-trimethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one chemical structure, C21H22N2O2, CAS 524047-05-0
(1Z)-1-[(4-Methoxyphenyl)imino]-4,4,6-trimethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one
CAS 524047-05-0C21H22N2O2
(1E)-1-[(4-Hydroxyphenyl)imino]-4,4,6-trimethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one chemical structure, C20H20N2O2, CAS 775289-43-5
(1E)-1-[(4-Hydroxyphenyl)imino]-4,4,6-trimethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one
CAS 775289-43-5C20H20N2O2
(1E)-1-[(4-Hydroxyphenyl)imino]-4,4,6,8-tetramethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one chemical structure, C21H22N2O2, CAS 777866-41-8
(1E)-1-[(4-Hydroxyphenyl)imino]-4,4,6,8-tetramethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one
CAS 777866-41-8C21H22N2O2