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Murcko scaffold

Ring system with 4 rings and 20 atoms

7 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
7
With full pages
4
Scaffold SMILES

O=C1C(=Nc2ccccc2)c2cccc3c2N1CC=C3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C(=Nc2ccccc2)c2cccc3c2N1CC=C3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

(1Z)-1-[(4-Methoxyphenyl)imino]-4,4,6,8-tetramethyl-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one chemical structure, C22H22N2O2, CAS 442868-54-4
(1Z)-1-[(4-Methoxyphenyl)imino]-4,4,6,8-tetramethyl-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one
CAS 442868-54-4C22H22N2O2
(1E)-1-[(4-Ethoxyphenyl)imino]-4,4,6,9-tetramethyl-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one chemical structure, C23H24N2O2, CAS 444558-61-6
(1E)-1-[(4-Ethoxyphenyl)imino]-4,4,6,9-tetramethyl-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one
CAS 444558-61-6C23H24N2O2
1-[(E)-4-Hydroxy-phenylimino]-4,4,6-trimethyl-1H,4H-pyrrolo[3,2,1-ij]quinolin-2-one chemical structure, C20H18N2O2, CAS 774559-76-1
1-[(E)-4-Hydroxy-phenylimino]-4,4,6-trimethyl-1H,4H-pyrrolo[3,2,1-ij]quinolin-2-one
CAS 774559-76-1C20H18N2O2
(1E)-1-[(4-Methoxyphenyl)imino]-4,4,6-trimethyl-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one chemical structure, C21H20N2O2, CAS 1164538-59-3
(1E)-1-[(4-Methoxyphenyl)imino]-4,4,6-trimethyl-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one
CAS 1164538-59-3C21H20N2O2
(1E)-8-Ethoxy-1-[(4-hydroxyphenyl)imino]-4,4,6-trimethyl-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one chemical structure, C22H22N2O3, CAS 775289-41-3
(1E)-8-Ethoxy-1-[(4-hydroxyphenyl)imino]-4,4,6-trimethyl-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one
CAS 775289-41-3C22H22N2O3
(1E)-1-[(3,5-Dimethoxyphenyl)imino]-4,4,6-trimethyl-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one chemical structure, C22H22N2O3, CAS 1164520-39-1
(1E)-1-[(3,5-Dimethoxyphenyl)imino]-4,4,6-trimethyl-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one
CAS 1164520-39-1C22H22N2O3
4,4,6,9-Tetramethyl-1-((4-methylphenyl)imino)-4H-pyrrolo(3,2,1-ij)quinolin-2(1H)-one chemical structure, C22H22N2O, CAS 827342-37-0
4,4,6,9-Tetramethyl-1-((4-methylphenyl)imino)-4H-pyrrolo(3,2,1-ij)quinolin-2(1H)-one
CAS 827342-37-0C22H22N2O