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Murcko scaffold

Ring system with 5 rings and 24 atoms

18 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
24
Chemicals
18
With full pages
3
Scaffold SMILES

O=C(OCC1c2ccccc2-c2ccccc21)N1CCC2(CC2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCC1c2ccccc2-c2ccccc21)N1CCC2(CC2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

(6S)-5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-azaspiro[2.4]heptane-6-carboxylic acid chemical structure, C22H21NO4, CAS 2170726-27-7
(6S)-5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-azaspiro[2.4]heptane-6-carboxylic acid
CAS 2170726-27-7C22H21NO4
5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-azaspiro[2.4]heptane-1-carboxylic acid chemical structure, C22H21NO4, CAS 1936276-26-4
5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-azaspiro[2.4]heptane-1-carboxylic acid
CAS 1936276-26-4C22H21NO4
5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-azaspiro[2.4]heptane-7-carboxylic acid chemical structure, C22H21NO4, CAS 2138525-93-4
5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-azaspiro[2.4]heptane-7-carboxylic acid
CAS 2138525-93-4C22H21NO4
2-[(6S)-5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-azaspiro[2.4]heptan-6-yl]acetic acid chemical structure, C23H23NO4, CAS 2219354-06-8
2-[(6S)-5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-azaspiro[2.4]heptan-6-yl]acetic acid
CAS 2219354-06-8C23H23NO4
5-(9H-Fluoren-9-ylmethoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic acid chemical structure, C22H21NO4, CAS 2940940-88-3
5-(9H-Fluoren-9-ylmethoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic acid
CAS 2940940-88-3C22H21NO4
5-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1,1-difluoro-5-azaspiro[2.4]heptane-6-carboxylic acid chemical structure, C22H19F2NO4, CAS 2171791-08-3
5-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1,1-difluoro-5-azaspiro[2.4]heptane-6-carboxylic acid
CAS 2171791-08-3C22H19F2NO4
5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-azaspiro[2.4]heptane-4-carboxylic acid chemical structure, C22H21NO4, CAS 2225144-90-9
5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-azaspiro[2.4]heptane-4-carboxylic acid
CAS 2225144-90-9C22H21NO4
5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-7-fluoro-5-azaspiro[2.4]heptane-7-carboxylic acid chemical structure, C22H20FNO4, CAS 2219419-12-0
5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-7-fluoro-5-azaspiro[2.4]heptane-7-carboxylic acid
CAS 2219419-12-0C22H20FNO4
5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,1-difluoro-5-azaspiro[2.4]heptane-4-carboxylic acid chemical structure, C22H19F2NO4, CAS 2225144-81-8
5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1,1-difluoro-5-azaspiro[2.4]heptane-4-carboxylic acid
CAS 2225144-81-8C22H19F2NO4
2-[(5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-azaspiro[2.4]heptan-7-yl)oxy]acetic acid chemical structure, C23H23NO5, CAS 2580243-78-1
2-[(5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-azaspiro[2.4]heptan-7-yl)oxy]acetic acid
CAS 2580243-78-1C23H23NO5
2-(5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-azaspiro[2.4]heptan-7-yl)acetic acid chemical structure, C23H23NO4, CAS 2639457-22-8
2-(5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-azaspiro[2.4]heptan-7-yl)acetic acid
CAS 2639457-22-8C23H23NO4
(9H-Fluoren-9-yl)methyl (6S)-6-(hydroxymethyl)-5-azaspiro[2.4]heptane-5-carboxylate chemical structure, C22H23NO3, CAS 2763895-03-8
(9H-Fluoren-9-yl)methyl (6S)-6-(hydroxymethyl)-5-azaspiro[2.4]heptane-5-carboxylate
CAS 2763895-03-8C22H23NO3
9H-Fluoren-9-ylmethyl 7-hydroxy-5-azaspiro[2.4]heptane-5-carboxylate chemical structure, C21H21NO3, CAS 2763912-46-3
9H-Fluoren-9-ylmethyl 7-hydroxy-5-azaspiro[2.4]heptane-5-carboxylate
CAS 2763912-46-3C21H21NO3
(9H-Fluoren-9-yl)methyl 7-(hydroxymethyl)-5-azaspiro[2.4]heptane-5-carboxylate chemical structure, C22H23NO3, CAS 2284989-71-3
(9H-Fluoren-9-yl)methyl 7-(hydroxymethyl)-5-azaspiro[2.4]heptane-5-carboxylate
CAS 2284989-71-3C22H23NO3
(9H-Fluoren-9-yl)methyl 6-ethynyl-5-azaspiro[2.4]heptane-5-carboxylate chemical structure, C23H21NO2, CAS 2770525-74-9
(9H-Fluoren-9-yl)methyl 6-ethynyl-5-azaspiro[2.4]heptane-5-carboxylate
CAS 2770525-74-9C23H21NO2
(9H-Fluoren-9-yl)methyl (6S)-6-ethynyl-5-azaspiro[2.4]heptane-5-carboxylate chemical structure, C23H21NO2, CAS 2770453-12-6
(9H-Fluoren-9-yl)methyl (6S)-6-ethynyl-5-azaspiro[2.4]heptane-5-carboxylate
CAS 2770453-12-6C23H21NO2
3-(5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-azaspiro[2.4]heptan-6-yl)prop-2-ynoic acid chemical structure, C24H21NO4, CAS 2913407-96-0
3-(5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-5-azaspiro[2.4]heptan-6-yl)prop-2-ynoic acid
CAS 2913407-96-0C24H21NO4
(6R)-5-(9H-Fluoren-9-ylmethoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic acid chemical structure, C22H21NO4, CAS 3053450-66-8
(6R)-5-(9H-Fluoren-9-ylmethoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic acid
CAS 3053450-66-8C22H21NO4