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Murcko scaffold

Ring system with 2 rings and 12 atoms

3 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
3
With full pages
3
Scaffold SMILES

C1=CC(c2ccncc2)C=CO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1=CC(c2ccncc2)C=CO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 3 of 3 chemicals

Methyl 6-amino-5-cyano-2-(2-methoxy-2-oxoethyl)-4-(pyridin-4-yl)-4H-pyran-3-carboxylate chemical structure, C16H15N3O5, CAS 364625-91-2
Methyl 6-amino-5-cyano-2-(2-methoxy-2-oxoethyl)-4-(pyridin-4-yl)-4H-pyran-3-carboxylate
CAS 364625-91-2C16H15N3O5
Diethyl 2-amino-6-methyl-4-(pyridin-4-yl)-4H-pyran-3,5-dicarboxylate chemical structure, C17H20N2O5, CAS 332164-19-9
Diethyl 2-amino-6-methyl-4-(pyridin-4-yl)-4H-pyran-3,5-dicarboxylate
CAS 332164-19-9C17H20N2O5
Ethyl 6-amino-5-cyano-2-(2-ethoxy-2-oxoethyl)-4-(pyridin-4-yl)-4H-pyran-3-carboxylate chemical structure, C18H19N3O5, CAS 300839-25-2
Ethyl 6-amino-5-cyano-2-(2-ethoxy-2-oxoethyl)-4-(pyridin-4-yl)-4H-pyran-3-carboxylate
CAS 300839-25-2C18H19N3O5