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Murcko scaffold

Ring system with 2 rings and 18 atoms

9 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
9
With full pages
6
Scaffold SMILES

O=C(NN=Cc1ccccc1)c1ccc(=O)[nH]n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1)c1ccc(=O)[nH]n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

1,6-Dihydro-6-oxo-3-pyridazinecarboxylic acid 2-[(2,4-dichlorophenyl)methylene]hydrazide chemical structure, C12H8Cl2N4O2, CAS 369403-41-8
1,6-Dihydro-6-oxo-3-pyridazinecarboxylic acid 2-[(2,4-dichlorophenyl)methylene]hydrazide
CAS 369403-41-8C12H8Cl2N4O2
1,6-Dihydro-6-oxo-3-pyridazinecarboxylic acid 2-[1-(4-chlorophenyl)ethylidene]hydrazide chemical structure, C13H11ClN4O2, CAS 369403-65-6
1,6-Dihydro-6-oxo-3-pyridazinecarboxylic acid 2-[1-(4-chlorophenyl)ethylidene]hydrazide
CAS 369403-65-6C13H11ClN4O2
N-[(E)-(2,5-Dimethoxyphenyl)methylideneamino]-6-oxo-1H-pyridazine-3-carboxamide chemical structure, C14H14N4O4, CAS 370576-08-2
N-[(E)-(2,5-Dimethoxyphenyl)methylideneamino]-6-oxo-1H-pyridazine-3-carboxamide
CAS 370576-08-2C14H14N4O4
(E)-N'-(4-(Dimethylamino)benzylidene)-6-oxo-1,6-dihydropyridazine-3-carbohydrazide chemical structure, C14H15N5O2, CAS 332040-95-6
(E)-N'-(4-(Dimethylamino)benzylidene)-6-oxo-1,6-dihydropyridazine-3-carbohydrazide
CAS 332040-95-6C14H15N5O2
6-Oxo-N'-((1E)-phenylmethylidene)-1,6-dihydropyridazine-3-carbohydrazide chemical structure, C12H10N4O2, CAS 332040-94-5
6-Oxo-N'-((1E)-phenylmethylidene)-1,6-dihydropyridazine-3-carbohydrazide
CAS 332040-94-5C12H10N4O2
N'-(2-Chlorobenzylidene)-6-oxo-1,6-dihydropyridazine-3-carbohydrazide chemical structure, C12H9ClN4O2, CAS 373615-94-2
N'-(2-Chlorobenzylidene)-6-oxo-1,6-dihydropyridazine-3-carbohydrazide
CAS 373615-94-2C12H9ClN4O2
N'-(5-Bromo-2-hydroxybenzylidene)-6-oxo-1,6-dihydro-3-pyridazinecarbohydrazide chemical structure, C12H9BrN4O3, CAS 477515-16-5
N'-(5-Bromo-2-hydroxybenzylidene)-6-oxo-1,6-dihydro-3-pyridazinecarbohydrazide
CAS 477515-16-5C12H9BrN4O3
N'-[(E)-(2-Hydroxy-3-methoxyphenyl)methylidene]-6-oxo-1,6-dihydropyridazine-3-carbohydrazide chemical structure, C13H12N4O4, CAS 370582-38-0
N'-[(E)-(2-Hydroxy-3-methoxyphenyl)methylidene]-6-oxo-1,6-dihydropyridazine-3-carbohydrazide
CAS 370582-38-0C13H12N4O4
N'-[(E)-(2-Hydroxyphenyl)methylidene]-6-oxo-1,6-dihydro-3-pyridazinecarbohydrazide chemical structure, C12H10N4O3, CAS 375358-20-6
N'-[(E)-(2-Hydroxyphenyl)methylidene]-6-oxo-1,6-dihydro-3-pyridazinecarbohydrazide
CAS 375358-20-6C12H10N4O3