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Murcko scaffold

Ring system with 4 rings and 23 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
10
With full pages
4
Scaffold SMILES

c1ccc(-n2cnnc2COc2cccc3cccnc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-n2cnnc2COc2cccc3cccnc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Methyl 2-[4-phenyl-5-(8-quinolyloxymethyl)-1,2,4-triazol-3-ylthio]acetate chemical structure, C21H18N4O3S, CAS 102061-77-8
Methyl 2-[4-phenyl-5-(8-quinolyloxymethyl)-1,2,4-triazol-3-ylthio]acetate
CAS 102061-77-8C21H18N4O3S
2-[[4-Phenyl-5-(quinolin-8-yloxymethyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C20H17N5O2S, CAS 333324-03-1
2-[[4-Phenyl-5-(quinolin-8-yloxymethyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 333324-03-1C20H17N5O2S
({5-[(8-Quinolinyloxy)methyl]-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl}thio)acetic acid chemical structure, C21H15F3N4O3S, CAS 690248-96-5
({5-[(8-Quinolinyloxy)methyl]-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl}thio)acetic acid
CAS 690248-96-5C21H15F3N4O3S
2-((5-((Quinolin-8-yloxy)methyl)-4-(3-(trifluoromethyl)phenyl)-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C21H16F3N5O2S, CAS 690249-08-2
2-((5-((Quinolin-8-yloxy)methyl)-4-(3-(trifluoromethyl)phenyl)-4H-1,2,4-triazol-3-yl)thio)acetamide
CAS 690249-08-2C21H16F3N5O2S
5-Chloro-8-[(5-methylsulfanyl-4-phenyl-1,2,4-triazol-3-yl)methoxy]quinoline chemical structure, C19H15ClN4OS, CAS 690247-13-3
5-Chloro-8-[(5-methylsulfanyl-4-phenyl-1,2,4-triazol-3-yl)methoxy]quinoline
CAS 690247-13-3C19H15ClN4OS
({4-(4-Chlorophenyl)-5-[(8-quinolinyloxy)methyl]-4H-1,2,4-triazol-3-yl}thio)acetic acid chemical structure, C20H15ClN4O3S, CAS 690247-02-0
({4-(4-Chlorophenyl)-5-[(8-quinolinyloxy)methyl]-4H-1,2,4-triazol-3-yl}thio)acetic acid
CAS 690247-02-0C20H15ClN4O3S
3-[[4-Phenyl-5-(quinolin-8-yloxymethyl)-1,2,4-triazol-3-yl]sulfanyl]propanoic acid chemical structure, C21H18N4O3S, CAS 835892-88-1
3-[[4-Phenyl-5-(quinolin-8-yloxymethyl)-1,2,4-triazol-3-yl]sulfanyl]propanoic acid
CAS 835892-88-1C21H18N4O3S
3-[[4-(4-Chlorophenyl)-5-(quinolin-8-yloxymethyl)-1,2,4-triazol-3-yl]sulfanyl]propanoic acid chemical structure, C21H17ClN4O3S, CAS 690249-83-3
3-[[4-(4-Chlorophenyl)-5-(quinolin-8-yloxymethyl)-1,2,4-triazol-3-yl]sulfanyl]propanoic acid
CAS 690249-83-3C21H17ClN4O3S
({4-Phenyl-5-[(quinolin-8-yloxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)acetic acid chemical structure, C20H16N4O3S, CAS 73511-70-3
({4-Phenyl-5-[(quinolin-8-yloxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)acetic acid
CAS 73511-70-3C20H16N4O3S
2-[[5-[(5-Chloroquinolin-8-yl)oxymethyl]-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetic acid chemical structure, C20H15ClN4O3S, CAS 940999-34-8
2-[[5-[(5-Chloroquinolin-8-yl)oxymethyl]-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetic acid
CAS 940999-34-8C20H15ClN4O3S