Murcko scaffold
Ring system with 5 rings and 32 atoms
20 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 32
- Chemicals
- 20
- With full pages
- 4
Scaffold SMILES
O=C(CN1C(=O)C2(SCC(=O)N2c2ccccc2)c2ccccc21)NCc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 20 of 20 chemicals
![N-[(2-Chlorophenyl)methyl]-2-[3'-(3-methylphenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]acetamide chemical structure, C26H22ClN3O3S, CAS 894546-43-1](/s/ILZRCIVUAYCIMR-UHFFFAOYSA-N.svg)
N-[(2-Chlorophenyl)methyl]-2-[3'-(3-methylphenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]acetamide
CAS 894546-43-1C26H22ClN3O3S
![2-[3'-(4-Fluorophenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]-N-[(4-methylphenyl)methyl]acetamide chemical structure, C26H22FN3O3S, CAS 894553-11-8](/s/NWELZERMBSJTOQ-UHFFFAOYSA-N.svg)
2-[3'-(4-Fluorophenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]-N-[(4-methylphenyl)methyl]acetamide
CAS 894553-11-8C26H22FN3O3S
![N-Benzyl-2-[3'-(3-chlorophenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]acetamide chemical structure, C25H20ClN3O3S, CAS 894555-69-2](/s/QLIULDQFCJBSBF-UHFFFAOYSA-N.svg)
N-Benzyl-2-[3'-(3-chlorophenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]acetamide
CAS 894555-69-2C25H20ClN3O3S
![N-Benzyl-2-(3'-(3,4-dimethylphenyl)-2,4'-dioxospiro[indoline-3,2'-thiazolidin]-1-yl)acetamide chemical structure, C27H25N3O3S, CAS 894556-97-9](/s/ULRCVCZJIMAXGN-UHFFFAOYSA-N.svg)
N-Benzyl-2-(3'-(3,4-dimethylphenyl)-2,4'-dioxospiro[indoline-3,2'-thiazolidin]-1-yl)acetamide
CAS 894556-97-9C27H25N3O3S
![2-(3'-(3,5-Dimethylphenyl)-2,4'-dioxospiro[indoline-3,2'-thiazolidin]-1-yl)-N-(4-methylbenzyl)acetamide chemical structure, C28H27N3O3S, CAS 894559-17-2](/s/MJSGMMKFXOLNAN-UHFFFAOYSA-N.svg)
2-(3'-(3,5-Dimethylphenyl)-2,4'-dioxospiro[indoline-3,2'-thiazolidin]-1-yl)-N-(4-methylbenzyl)acetamide
CAS 894559-17-2C28H27N3O3S
![N-Benzyl-2-[3'-(4-methoxyphenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]acetamide chemical structure, C26H23N3O4S, CAS 894560-31-7](/s/USHSNCNZIKZXMX-UHFFFAOYSA-N.svg)
N-Benzyl-2-[3'-(4-methoxyphenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]acetamide
CAS 894560-31-7C26H23N3O4S
![N-[(2-Chlorophenyl)methyl]-2-[3'-(3,4-dimethylphenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]acetamide chemical structure, C27H24ClN3O3S, CAS 892299-42-2](/s/JHUGHICWTKIJFW-UHFFFAOYSA-N.svg)
N-[(2-Chlorophenyl)methyl]-2-[3'-(3,4-dimethylphenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]acetamide
CAS 892299-42-2C27H24ClN3O3S
![N-Benzyl-2-[3'-(4-fluorophenyl)-5-methyl-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]acetamide chemical structure, C26H22FN3O3S, CAS 899743-43-2](/s/HFXUUCSJWNBYTM-UHFFFAOYSA-N.svg)
N-Benzyl-2-[3'-(4-fluorophenyl)-5-methyl-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]acetamide
CAS 899743-43-2C26H22FN3O3S
![2-[3'-(4-Fluorophenyl)-5-methyl-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]-N-[(4-methylphenyl)methyl]acetamide chemical structure, C27H24FN3O3S, CAS 899743-49-8](/s/ZYODSMHLYQEDRO-UHFFFAOYSA-N.svg)
2-[3'-(4-Fluorophenyl)-5-methyl-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]-N-[(4-methylphenyl)methyl]acetamide
CAS 899743-49-8C27H24FN3O3S
![N-Benzyl-2-(3'-(4-fluorophenyl)-7-methyl-2,4'-dioxospiro[indoline-3,2'-thiazolidin]-1-yl)acetamide chemical structure, C26H22FN3O3S, CAS 899743-55-6](/s/PRZOBBLTGVPNRC-UHFFFAOYSA-N.svg)
N-Benzyl-2-(3'-(4-fluorophenyl)-7-methyl-2,4'-dioxospiro[indoline-3,2'-thiazolidin]-1-yl)acetamide
CAS 899743-55-6C26H22FN3O3S
![2-[3'-(4-Fluorophenyl)-7-methyl-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]-N-[(4-methylphenyl)methyl]acetamide chemical structure, C27H24FN3O3S, CAS 899987-23-6](/s/KQUXKYDVPGGICZ-UHFFFAOYSA-N.svg)
2-[3'-(4-Fluorophenyl)-7-methyl-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]-N-[(4-methylphenyl)methyl]acetamide
CAS 899987-23-6C27H24FN3O3S
![N-Benzyl-2-(3'-(3,5-dimethylphenyl)-2,4'-dioxospiro[indoline-3,2'-thiazolidin]-1-yl)acetamide chemical structure, C27H25N3O3S, CAS 894558-59-9](/s/NIBGXXSPMCJDRX-UHFFFAOYSA-N.svg)
N-Benzyl-2-(3'-(3,5-dimethylphenyl)-2,4'-dioxospiro[indoline-3,2'-thiazolidin]-1-yl)acetamide
CAS 894558-59-9C27H25N3O3S
![N-Benzyl-2-(3'-(4-chlorophenyl)-2,4'-dioxospiro[indoline-3,2'-thiazolidin]-1-yl)acetamide chemical structure, C25H20ClN3O3S, CAS 894554-38-2](/s/BVNUCUGLBJOWFS-UHFFFAOYSA-N.svg)
N-Benzyl-2-(3'-(4-chlorophenyl)-2,4'-dioxospiro[indoline-3,2'-thiazolidin]-1-yl)acetamide
CAS 894554-38-2C25H20ClN3O3S
![2-[3'-(4-Chlorophenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]-N-[(4-methylphenyl)methyl]acetamide chemical structure, C26H22ClN3O3S, CAS 894554-93-9](/s/NAFAMSLWNKBRAD-UHFFFAOYSA-N.svg)
2-[3'-(4-Chlorophenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]-N-[(4-methylphenyl)methyl]acetamide
CAS 894554-93-9C26H22ClN3O3S
![2-[3'-(3-Chlorophenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]-N-[(4-methylphenyl)methyl]acetamide chemical structure, C26H22ClN3O3S, CAS 894556-20-8](/s/DQLUQYMTADYAIT-UHFFFAOYSA-N.svg)
2-[3'-(3-Chlorophenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]-N-[(4-methylphenyl)methyl]acetamide
CAS 894556-20-8C26H22ClN3O3S
![N-Benzyl-2-[3'-(3-fluorophenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]acetamide chemical structure, C25H20FN3O3S, CAS 894550-33-5](/s/WTBHOPDHDIFUJD-UHFFFAOYSA-N.svg)
N-Benzyl-2-[3'-(3-fluorophenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]acetamide
CAS 894550-33-5C25H20FN3O3S
![N-Benzyl-2-[3'-(4-fluorophenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]acetamide chemical structure, C25H20FN3O3S, CAS 894552-39-7](/s/BEKNFPFRHZTBQZ-UHFFFAOYSA-N.svg)
N-Benzyl-2-[3'-(4-fluorophenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]acetamide
CAS 894552-39-7C25H20FN3O3S
![N-(2-Chlorobenzyl)-2-(3'-(4-fluorophenyl)-2,4'-dioxospiro[indoline-3,2'-thiazolidin]-1-yl)acetamide chemical structure, C25H19ClFN3O3S, CAS 894552-63-7](/s/IMGKTUYUXWVROO-UHFFFAOYSA-N.svg)
N-(2-Chlorobenzyl)-2-(3'-(4-fluorophenyl)-2,4'-dioxospiro[indoline-3,2'-thiazolidin]-1-yl)acetamide
CAS 894552-63-7C25H19ClFN3O3S
![2-[3'-(3,4-Dimethylphenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]-N-[(4-methylphenyl)methyl]acetamide chemical structure, C28H27N3O3S, CAS 894557-50-7](/s/SFYXASFIZWHQKI-UHFFFAOYSA-N.svg)
2-[3'-(3,4-Dimethylphenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]-N-[(4-methylphenyl)methyl]acetamide
CAS 894557-50-7C28H27N3O3S
![2-[3'-(4-Methoxyphenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]-N-[(4-methylphenyl)methyl]acetamide chemical structure, C27H25N3O4S, CAS 894560-87-3](/s/AOKIMHBUEGAWOV-UHFFFAOYSA-N.svg)
2-[3'-(4-Methoxyphenyl)-2,4'-dioxo-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-1-yl]-N-[(4-methylphenyl)methyl]acetamide
CAS 894560-87-3C27H25N3O4S