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Murcko scaffold

Ring system with 4 rings and 28 atoms

24 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
24
With full pages
5
Scaffold SMILES

O=C(Nc1ccc(N2CCN(C(=O)c3ccco3)CC2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(N2CCN(C(=O)c3ccco3)CC2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

2-Fluoro-N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]benzamide chemical structure, C22H20FN3O3, CAS 674337-14-5
2-Fluoro-N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]benzamide
CAS 674337-14-5C22H20FN3O3
N-[3-Chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-3,5-dimethoxybenzamide chemical structure, C24H24ClN3O5, CAS 831250-71-6
N-[3-Chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-3,5-dimethoxybenzamide
CAS 831250-71-6C24H24ClN3O5
3-Bromo-N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-4-methoxybenzamide chemical structure, C23H22BrN3O4, CAS 673497-17-1
3-Bromo-N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-4-methoxybenzamide
CAS 673497-17-1C23H22BrN3O4
N-[4-[4-(Furan-2-carbonyl)piperazin-1-yl]phenyl]-3,5-dimethylbenzamide chemical structure, C24H25N3O3, CAS 706767-21-7
N-[4-[4-(Furan-2-carbonyl)piperazin-1-yl]phenyl]-3,5-dimethylbenzamide
CAS 706767-21-7C24H25N3O3
N-[3-Chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-2,4-dimethylbenzamide chemical structure, C24H24ClN3O3, CAS 674813-20-8
N-[3-Chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-2,4-dimethylbenzamide
CAS 674813-20-8C24H24ClN3O3
3-Chloro-N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-4-methylbenzamide chemical structure, C23H22ClN3O3, CAS 674306-20-8
3-Chloro-N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-4-methylbenzamide
CAS 674306-20-8C23H22ClN3O3
2-Bromo-N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]benzamide chemical structure, C22H20BrN3O3, CAS 688031-20-1
2-Bromo-N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]benzamide
CAS 688031-20-1C22H20BrN3O3
N-[4-[4-(Furan-2-carbonyl)piperazin-1-yl]phenyl]-4-propan-2-ylbenzamide chemical structure, C25H27N3O3, CAS 838812-94-5
N-[4-[4-(Furan-2-carbonyl)piperazin-1-yl]phenyl]-4-propan-2-ylbenzamide
CAS 838812-94-5C25H27N3O3
N-[4-[4-(Furan-2-carbonyl)piperazin-1-yl]phenyl]-4-(2-methylpropoxy)benzamide chemical structure, C26H29N3O4, CAS 892187-63-2
N-[4-[4-(Furan-2-carbonyl)piperazin-1-yl]phenyl]-4-(2-methylpropoxy)benzamide
CAS 892187-63-2C26H29N3O4
N-[4-[4-(Furan-2-carbonyl)piperazin-1-yl]phenyl]-4-nitrobenzamide chemical structure, C22H20N4O5, CAS 766523-71-1
N-[4-[4-(Furan-2-carbonyl)piperazin-1-yl]phenyl]-4-nitrobenzamide
CAS 766523-71-1C22H20N4O5
N-[3-Chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-4-methylbenzamide chemical structure, C23H22ClN3O3, CAS 833443-30-4
N-[3-Chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-4-methylbenzamide
CAS 833443-30-4C23H22ClN3O3
N-[3-Chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-2,4-dimethoxybenzamide chemical structure, C24H24ClN3O5, CAS 915913-44-9
N-[3-Chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-2,4-dimethoxybenzamide
CAS 915913-44-9C24H24ClN3O5
3-Butoxy-N-[3-chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]benzamide chemical structure, C26H28ClN3O4, CAS 842114-03-8
3-Butoxy-N-[3-chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]benzamide
CAS 842114-03-8C26H28ClN3O4
3,5-Dichloro-N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-4-methoxybenzamide chemical structure, C23H21Cl2N3O4, CAS 842118-44-9
3,5-Dichloro-N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-4-methoxybenzamide
CAS 842118-44-9C23H21Cl2N3O4
N-[4-[4-(Furan-2-carbonyl)piperazin-1-yl]phenyl]-2-methoxybenzamide chemical structure, C23H23N3O4, CAS 876899-49-9
N-[4-[4-(Furan-2-carbonyl)piperazin-1-yl]phenyl]-2-methoxybenzamide
CAS 876899-49-9C23H23N3O4
N-[4-[4-(Furan-2-carbonyl)piperazin-1-yl]phenyl]-2-methylbenzamide chemical structure, C23H23N3O3, CAS 688031-79-0
N-[4-[4-(Furan-2-carbonyl)piperazin-1-yl]phenyl]-2-methylbenzamide
CAS 688031-79-0C23H23N3O3
N-{3-Chloro-4-[4-(2-furoyl)-1-piperazinyl]phenyl}-2-methoxybenzamide chemical structure, C23H22ClN3O4, CAS 876886-55-4
N-{3-Chloro-4-[4-(2-furoyl)-1-piperazinyl]phenyl}-2-methoxybenzamide
CAS 876886-55-4C23H22ClN3O4
N-[3-Chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]benzamide chemical structure, C22H20ClN3O3, CAS 876886-63-4
N-[3-Chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]benzamide
CAS 876886-63-4C22H20ClN3O3
N-[3-Chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-4-fluorobenzamide chemical structure, C22H19ClFN3O3, CAS 876886-67-8
N-[3-Chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-4-fluorobenzamide
CAS 876886-67-8C22H19ClFN3O3
N-[3-Chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-3-methylbenzamide chemical structure, C23H22ClN3O3, CAS 876886-79-2
N-[3-Chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-3-methylbenzamide
CAS 876886-79-2C23H22ClN3O3
N-[3-Chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-2-fluorobenzamide chemical structure, C22H19ClFN3O3, CAS 876886-91-8
N-[3-Chloro-4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-2-fluorobenzamide
CAS 876886-91-8C22H19ClFN3O3
4-Bromo-N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]benzamide chemical structure, C22H20BrN3O3, CAS 674338-47-7
4-Bromo-N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]benzamide
CAS 674338-47-7C22H20BrN3O3
5-Chloro-N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-2-methoxybenzamide chemical structure, C23H22ClN3O4, CAS 847474-48-0
5-Chloro-N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]-2-methoxybenzamide
CAS 847474-48-0C23H22ClN3O4
4-Ethyl-N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]benzamide chemical structure, C24H25N3O3, CAS 878708-43-1
4-Ethyl-N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]benzamide
CAS 878708-43-1C24H25N3O3