CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 26 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
10
With full pages
3
Scaffold SMILES

O=C(C=Cc1ccc(-c2ccccc2)o1)Nc1cccc2ncccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccc(-c2ccccc2)o1)Nc1cccc2ncccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

2-Cyano-3-(5-phenyl-furan-2-yl)-N-quinolin-5-yl-acrylamide chemical structure, C23H15N3O2, CAS 303794-04-9
2-Cyano-3-(5-phenyl-furan-2-yl)-N-quinolin-5-yl-acrylamide
CAS 303794-04-9C23H15N3O2
2-Cyano-N-(5-quinolinyl)-3-(5-(3-(trifluoromethyl)phenyl)-2-furyl)acrylamide chemical structure, C24H14F3N3O2, CAS 304896-25-1
2-Cyano-N-(5-quinolinyl)-3-(5-(3-(trifluoromethyl)phenyl)-2-furyl)acrylamide
CAS 304896-25-1C24H14F3N3O2
3-(5-(2-Chlorophenyl)furan-2-yl)-2-cyano-N-(quinolin-5-yl)acrylamide chemical structure, C23H14ClN3O2, CAS 304896-26-2
3-(5-(2-Chlorophenyl)furan-2-yl)-2-cyano-N-(quinolin-5-yl)acrylamide
CAS 304896-26-2C23H14ClN3O2
2-Cyano-3-(5-(2,3-dichlorophenyl)furan-2-yl)-N-(quinolin-5-yl)acrylamide chemical structure, C23H13Cl2N3O2, CAS 304896-29-5
2-Cyano-3-(5-(2,3-dichlorophenyl)furan-2-yl)-N-(quinolin-5-yl)acrylamide
CAS 304896-29-5C23H13Cl2N3O2
3-(5-(4-Chlorophenyl)-2-furyl)-2-cyano-N-(5-quinolinyl)acrylamide chemical structure, C23H14ClN3O2, CAS 304896-27-3
3-(5-(4-Chlorophenyl)-2-furyl)-2-cyano-N-(5-quinolinyl)acrylamide
CAS 304896-27-3C23H14ClN3O2
(E)-2-Cyano-3-[5-(2,4-dichlorophenyl)furan-2-yl]-N-quinolin-5-ylprop-2-enamide chemical structure, C23H13Cl2N3O2, CAS 327062-79-3
(E)-2-Cyano-3-[5-(2,4-dichlorophenyl)furan-2-yl]-N-quinolin-5-ylprop-2-enamide
CAS 327062-79-3C23H13Cl2N3O2
(E)-3-[5-(3-Chlorophenyl)furan-2-yl]-2-cyano-N-quinolin-5-ylprop-2-enamide chemical structure, C23H14ClN3O2, CAS 301312-35-6
(E)-3-[5-(3-Chlorophenyl)furan-2-yl]-2-cyano-N-quinolin-5-ylprop-2-enamide
CAS 301312-35-6C23H14ClN3O2
Agk-2 chemical structure, C23H13Cl2N3O2, CAS 304896-28-4
Agk-2
CAS 304896-28-4C23H13Cl2N3O2
2-Cyano-3-(5-{4-[(difluoromethyl)sulfanyl]phenyl}furan-2-yl)-N-(quinolin-5-yl)prop-2-enamide chemical structure, C24H15F2N3O2S, CAS 326916-67-0
2-Cyano-3-(5-{4-[(difluoromethyl)sulfanyl]phenyl}furan-2-yl)-N-(quinolin-5-yl)prop-2-enamide
CAS 326916-67-0C24H15F2N3O2S
AGK-2 hydrochloride chemical structure, C23H14Cl3N3O2, CAS 2138805-02-2
AGK-2 hydrochloride
CAS 2138805-02-2C23H14Cl3N3O2