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Murcko scaffold

2-(1,2,3,4-Tetrahydroisoquinolin-2-yl)quinoline scaffold

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
6
With full pages
3
Scaffold SMILES

c1ccc2c(c1)CCN(c1ccc3ccccc3n1)C2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(1,2,3,4-Tetrahydroisoquinolin-2-yl)quinoline page
Murcko scaffold c1ccc2c(c1)CCN(c1ccc3ccccc3n1)C2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

UK 52046 chemical structure, C23H29N3O7S, CAS 118931-00-3
UK 52046
CAS 118931-00-3C23H29N3O7S
Abanoquil chemical structure, C22H25N3O4, CAS 90402-40-7
Abanoquil
CAS 90402-40-7C22H25N3O4
2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)quinoline chemical structure, C20H20N2O2, CAS 731012-34-3
2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)quinoline
CAS 731012-34-3C20H20N2O2
2-(1,2,3,4-Tetrahydroisoquinolin-2-yl)quinoline chemical structure, C18H16N2, CAS 897290-74-3
2-(1,2,3,4-Tetrahydroisoquinolin-2-yl)quinoline
CAS 897290-74-3C18H16N2
2-(1,2,3,4-Tetrahydroisoquinolin-2-yl)quinolin-6-amine chemical structure, C18H17N3, CAS 1154583-56-8
2-(1,2,3,4-Tetrahydroisoquinolin-2-yl)quinolin-6-amine
CAS 1154583-56-8C18H17N3
2-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)quinoline-3-carbonitrile chemical structure, C21H19N3O2, CAS 2330055-94-0
2-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)quinoline-3-carbonitrile
CAS 2330055-94-0C21H19N3O2