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Murcko scaffold

Ring system with 4 rings and 21 atoms

77 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
77
With full pages
11
Scaffold SMILES

O=c1c(-c2ccc3c(c2)OCCO3)coc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c(-c2ccc3c(c2)OCCO3)coc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 77 chemicals

3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-4-oxo-4H-chromen-7-yl acetate chemical structure, C19H14O6, CAS 170511-24-7
3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-4-oxo-4H-chromen-7-yl acetate
CAS 170511-24-7C19H14O6
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-7-methoxychromen-4-one chemical structure, C18H14O5, CAS 96754-83-5
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-7-methoxychromen-4-one
CAS 96754-83-5C18H14O5
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-6-ethyl-7-methoxychromen-4-one chemical structure, C20H18O5, CAS 170511-22-5
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-6-ethyl-7-methoxychromen-4-one
CAS 170511-22-5C20H18O5
Methyl 2-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-ethyl-4-oxochromen-7-yl]oxyacetate chemical structure, C22H20O7, CAS 180077-47-8
Methyl 2-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-ethyl-4-oxochromen-7-yl]oxyacetate
CAS 180077-47-8C22H20O7
3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2,6-diethyl-4-oxo-4H-chromen-7-yl propionate chemical structure, C24H24O6, CAS 159647-58-2
3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2,6-diethyl-4-oxo-4H-chromen-7-yl propionate
CAS 159647-58-2C24H24O6
3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-ethyl-7-isopropoxy-4H-chromen-4-one chemical structure, C22H22O5, CAS 159647-67-3
3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-ethyl-7-isopropoxy-4H-chromen-4-one
CAS 159647-67-3C22H22O5
[5-Acetyloxy-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-4-oxochromen-7-yl] acetate chemical structure, C22H18O8, CAS 169903-83-7
[5-Acetyloxy-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-4-oxochromen-7-yl] acetate
CAS 169903-83-7C22H18O8
3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-7-isopropoxy-2-methyl-4H-chromen-4-one chemical structure, C21H20O5, CAS 202843-20-7
3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-7-isopropoxy-2-methyl-4H-chromen-4-one
CAS 202843-20-7C21H20O5
Methyl {[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,6-diethyl-4-oxo-4H-chromen-7-yl]oxy}acetate chemical structure, C24H24O7, CAS 180077-41-2
Methyl {[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,6-diethyl-4-oxo-4H-chromen-7-yl]oxy}acetate
CAS 180077-41-2C24H24O7
Methyl {[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-6-ethyl-2-methyl-4-oxo-4H-chromen-7-yl]oxy}acetate chemical structure, C23H22O7, CAS 227094-60-2
Methyl {[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-6-ethyl-2-methyl-4-oxo-4H-chromen-7-yl]oxy}acetate
CAS 227094-60-2C23H22O7
Methyl {[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-4-oxo-4H-chromen-7-yl]oxy}acetate chemical structure, C21H18O7, CAS 227094-55-5
Methyl {[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-4-oxo-4H-chromen-7-yl]oxy}acetate
CAS 227094-55-5C21H18O7
3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-methyl-4-oxo-6-propyl-4H-chromen-7-yl acetate chemical structure, C23H22O6, CAS 170511-29-2
3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-methyl-4-oxo-6-propyl-4H-chromen-7-yl acetate
CAS 170511-29-2C23H22O6
3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-ethyl-4-oxo-4H-chromen-7-yl acetate chemical structure, C21H18O6, CAS 170807-09-7
3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-ethyl-4-oxo-4H-chromen-7-yl acetate
CAS 170807-09-7C21H18O6
3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-6-ethyl-2-methyl-4-oxo-4H-chromen-7-yl acetate chemical structure, C22H20O6, CAS 170511-28-1
3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-6-ethyl-2-methyl-4-oxo-4H-chromen-7-yl acetate
CAS 170511-28-1C22H20O6
3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-6-ethyl-4-oxo-4H-chromen-7-yl acetate chemical structure, C21H18O6, CAS 170511-25-8
3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-6-ethyl-4-oxo-4H-chromen-7-yl acetate
CAS 170511-25-8C21H18O6
3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-4-oxo-4H-chromen-7-yl diethylcarbamate chemical structure, C22H21NO6, CAS 724740-71-0
3-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-4-oxo-4H-chromen-7-yl diethylcarbamate
CAS 724740-71-0C22H21NO6
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-oxo-4H-chromen-7-yl dimethylcarbamate chemical structure, C20H17NO6, CAS 724740-81-2
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-oxo-4H-chromen-7-yl dimethylcarbamate
CAS 724740-81-2C20H17NO6
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-7-ethoxy-2,8-dimethyl-4H-chromen-4-one chemical structure, C21H20O5, CAS 202914-38-3
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-7-ethoxy-2,8-dimethyl-4H-chromen-4-one
CAS 202914-38-3C21H20O5
Ethyl 2-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-oxo-2-(trifluoromethyl)chromen-7-yl]oxyacetate chemical structure, C22H17F3O7, CAS 294854-98-1
Ethyl 2-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-oxo-2-(trifluoromethyl)chromen-7-yl]oxyacetate
CAS 294854-98-1C22H17F3O7
[3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-oxo-2-(trifluoromethyl)chromen-7-yl] acetate chemical structure, C20H13F3O6, CAS 294854-33-4
[3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-oxo-2-(trifluoromethyl)chromen-7-yl] acetate
CAS 294854-33-4C20H13F3O6
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-6-ethyl-7-[(2-methyl-2-propenyl)oxy]-4H-chromen-4-one chemical structure, C23H22O5, CAS 610762-30-6
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-6-ethyl-7-[(2-methyl-2-propenyl)oxy]-4H-chromen-4-one
CAS 610762-30-6C23H22O5
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-6-ethyl-7-methoxy-2-methylchromen-4-one chemical structure, C21H20O5, CAS 170511-34-9
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-6-ethyl-7-methoxy-2-methylchromen-4-one
CAS 170511-34-9C21H20O5
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-6-ethyl-7-propan-2-yloxy-2-propylchromen-4-one chemical structure, C25H28O5, CAS 180077-46-7
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-6-ethyl-7-propan-2-yloxy-2-propylchromen-4-one
CAS 180077-46-7C25H28O5
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-methyl-4-oxo-4H-chromen-7-yl acetate chemical structure, C20H16O6, CAS 170511-27-0
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-methyl-4-oxo-4H-chromen-7-yl acetate
CAS 170511-27-0C20H16O6