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Murcko scaffold

Ring system with 3 rings and 20 atoms

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
21
With full pages
14
Scaffold SMILES

O=C(Nc1ccc(N2CCNCC2)cc1)c1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(N2CCNCC2)cc1)c1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

N-[4-(4-Butanoylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C19H23N3O3, CAS 680584-67-2
N-[4-(4-Butanoylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 680584-67-2C19H23N3O3
N-[4-(4-Methylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C16H19N3O2, CAS 640241-31-2
N-[4-(4-Methylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 640241-31-2C16H19N3O2
N-[4-(4-Acetyl-1-piperazinyl)phenyl]-2-furamide chemical structure, C17H19N3O3, CAS 353760-65-3
N-[4-(4-Acetyl-1-piperazinyl)phenyl]-2-furamide
CAS 353760-65-3C17H19N3O3
N-[3-Chloro-4-(4-ethylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C17H20ClN3O2, CAS 674812-55-6
N-[3-Chloro-4-(4-ethylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 674812-55-6C17H20ClN3O2
5-Bromo-N-[3-chloro-4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]furan-2-carboxamide chemical structure, C19H21BrClN3O3, CAS 674330-52-0
5-Bromo-N-[3-chloro-4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]furan-2-carboxamide
CAS 674330-52-0C19H21BrClN3O3
5-Bromo-N-[4-(4-methylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C16H18BrN3O2, CAS 640241-33-4
5-Bromo-N-[4-(4-methylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 640241-33-4C16H18BrN3O2
5-Bromo-N-[4-(4-isobutyryl-1-piperazinyl)phenyl]-2-furamide chemical structure, C19H22BrN3O3, CAS 674355-45-4
5-Bromo-N-[4-(4-isobutyryl-1-piperazinyl)phenyl]-2-furamide
CAS 674355-45-4C19H22BrN3O3
N-[4-(4-Methylsulfonylpiperazin-1-yl)phenyl]-5-nitrofuran-2-carboxamide chemical structure, C16H18N4O6S, CAS 674816-49-0
N-[4-(4-Methylsulfonylpiperazin-1-yl)phenyl]-5-nitrofuran-2-carboxamide
CAS 674816-49-0C16H18N4O6S
N-[4-[4-(2-Methylpropanoyl)piperazin-1-yl]phenyl]-5-nitrofuran-2-carboxamide chemical structure, C19H22N4O5, CAS 672913-39-2
N-[4-[4-(2-Methylpropanoyl)piperazin-1-yl]phenyl]-5-nitrofuran-2-carboxamide
CAS 672913-39-2C19H22N4O5
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-5-bromofuran-2-carboxamide chemical structure, C17H18BrN3O3, CAS 355412-80-5
N-[4-(4-Acetylpiperazin-1-yl)phenyl]-5-bromofuran-2-carboxamide
CAS 355412-80-5C17H18BrN3O3
N-[4-(4-Propanoylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C18H21N3O3, CAS 688333-50-8
N-[4-(4-Propanoylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 688333-50-8C18H21N3O3
5-Bromo-N-[4-(4-butanoylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C19H22BrN3O3, CAS 688333-51-9
5-Bromo-N-[4-(4-butanoylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 688333-51-9C19H22BrN3O3
5-Bromo-N-[3-chloro-4-(4-ethylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C17H19BrClN3O2, CAS 673491-55-9
5-Bromo-N-[3-chloro-4-(4-ethylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 673491-55-9C17H19BrClN3O2
5-Bromo-N-[3-chloro-4-(4-propanoylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C18H19BrClN3O3, CAS 831250-49-8
5-Bromo-N-[3-chloro-4-(4-propanoylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 831250-49-8C18H19BrClN3O3
N-[3-Chloro-4-(4-propanoylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C18H20ClN3O3, CAS 839697-27-7
N-[3-Chloro-4-(4-propanoylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 839697-27-7C18H20ClN3O3
N-[4-(4-Ethylpiperazin-1-yl)phenyl]furan-2-carboxamide chemical structure, C17H21N3O2, CAS 499190-74-8
N-[4-(4-Ethylpiperazin-1-yl)phenyl]furan-2-carboxamide
CAS 499190-74-8C17H21N3O2
2-Furancarboxamide, N-[4-(4-methyl-1-piperazinyl)phenyl]-5-nitro- chemical structure, C16H18N4O4, CAS 831203-59-9
2-Furancarboxamide, N-[4-(4-methyl-1-piperazinyl)phenyl]-5-nitro-
CAS 831203-59-9C16H18N4O4
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]furan-2-carboxamide chemical structure, C20H25N3O3, CAS 878416-02-5
N-[4-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]phenyl]furan-2-carboxamide
CAS 878416-02-5C20H25N3O3
N-[4-[4-(3-Methylbutanoyl)piperazin-1-yl]phenyl]furan-2-carboxamide chemical structure, C20H25N3O3, CAS 892673-89-1
N-[4-[4-(3-Methylbutanoyl)piperazin-1-yl]phenyl]furan-2-carboxamide
CAS 892673-89-1C20H25N3O3
N-[3-Chloro-4-[4-(3-methylbutanoyl)piperazin-1-yl]phenyl]furan-2-carboxamide chemical structure, C20H24ClN3O3, CAS 892674-61-2
N-[3-Chloro-4-[4-(3-methylbutanoyl)piperazin-1-yl]phenyl]furan-2-carboxamide
CAS 892674-61-2C20H24ClN3O3
N-[3-Chloro-4-[4-(2,2-dimethylpropanoyl)piperazin-1-yl]phenyl]-5-nitrofuran-2-carboxamide chemical structure, C20H23ClN4O5, CAS 898117-96-9
N-[3-Chloro-4-[4-(2,2-dimethylpropanoyl)piperazin-1-yl]phenyl]-5-nitrofuran-2-carboxamide
CAS 898117-96-9C20H23ClN4O5