CompoundList
Sign in
Murcko scaffold

4-Thiouracil scaffold

39 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
8
Chemicals
39
With full pages
5
Scaffold SMILES

O=c1[nH]ccc(=S)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Thiouracil page
Murcko scaffold O=c1[nH]ccc(=S)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

1,3-Dimethyl-4-thiouracil chemical structure, C6H8N2OS, CAS 49785-67-3
1,3-Dimethyl-4-thiouracil
CAS 49785-67-3C6H8N2OS
6-Methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one chemical structure, C5H6N2OS, CAS 638-13-1
6-Methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one
CAS 638-13-1C5H6N2OS
Ethyl 2-oxo-6-thioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate chemical structure, C7H8N2O3S, CAS 332025-18-0
Ethyl 2-oxo-6-thioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate
CAS 332025-18-0C7H8N2O3S
6-Amino-4-sulfanylidene-1H-pyrimidin-2-one chemical structure, C4H5N3OS, CAS 1073-82-1
6-Amino-4-sulfanylidene-1H-pyrimidin-2-one
CAS 1073-82-1C4H5N3OS
4-Thiouracil chemical structure, C4H4N2OS, CAS 591-28-6
4-Thiouracil
CAS 591-28-6C4H4N2OS
5-Fluoro-4-mercapto-2-hydroxypyrimidine chemical structure, C4H3FN2OS, CAS 671-41-0
5-Fluoro-4-mercapto-2-hydroxypyrimidine
CAS 671-41-0C4H3FN2OS
Ethyl 6-methyl-2-oxo-4-sulfanylidene-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C8H10N2O3S, CAS 13996-05-9
Ethyl 6-methyl-2-oxo-4-sulfanylidene-1,2,3,4-tetrahydropyrimidine-5-carboxylate
CAS 13996-05-9C8H10N2O3S
1,2,3,6-Tetrahydro-5-methyl-2-oxo-6-thioxo-4-pyrimidinecarboxylic acid chemical structure, C6H6N2O3S, CAS 74039-19-3
1,2,3,6-Tetrahydro-5-methyl-2-oxo-6-thioxo-4-pyrimidinecarboxylic acid
CAS 74039-19-3C6H6N2O3S
Methyl 5-amino-2-oxo-6-thioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate chemical structure, C6H7N3O3S, CAS 502184-50-1
Methyl 5-amino-2-oxo-6-thioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate
CAS 502184-50-1C6H7N3O3S
4-Thioorotate chemical structure, C5H4N2O3S, CAS 6303-57-7
4-Thioorotate
CAS 6303-57-7C5H4N2O3S
5-Bromo-4-sulfanylidene-3,4-dihydropyrimidin-2(1H)-one chemical structure, C4H3BrN2OS, CAS 72812-45-4
5-Bromo-4-sulfanylidene-3,4-dihydropyrimidin-2(1H)-one
CAS 72812-45-4C4H3BrN2OS
Methyl 6-methyl-2-oxo-4-sulfanyl-1,2-dihydropyrimidine-5-carboxylate chemical structure, C7H8N2O3S, CAS 863669-54-9
Methyl 6-methyl-2-oxo-4-sulfanyl-1,2-dihydropyrimidine-5-carboxylate
CAS 863669-54-9C7H8N2O3S
5-Methoxy-4-sulfanylidene-1H-pyrimidin-2-one chemical structure, C5H6N2O2S, CAS 6943-41-5
5-Methoxy-4-sulfanylidene-1H-pyrimidin-2-one
CAS 6943-41-5C5H6N2O2S
2(1H)-pyrimidinone, 5-chloro-3,4-dihydro-4-thioxo- chemical structure, C4H3ClN2OS, CAS 63331-62-4
2(1H)-pyrimidinone, 5-chloro-3,4-dihydro-4-thioxo-
CAS 63331-62-4C4H3ClN2OS
5-Methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one chemical structure, C5H6N2OS, CAS 35455-79-9
5-Methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one
CAS 35455-79-9C5H6N2OS
1-Methyl-4-thiouracil chemical structure, C5H6N2OS, CAS 35455-86-8
1-Methyl-4-thiouracil
CAS 35455-86-8C5H6N2OS
RefChem:314139 chemical structure, C9H13BrN2OS, CAS 24561-92-0
RefChem:314139
CAS 24561-92-0C9H13BrN2OS
6-Methyl-2-oxo-4-sulfanyl-1,2-dihydropyrimidine-5-carbonitrile chemical structure, C6H5N3OS, CAS 2228-22-0
6-Methyl-2-oxo-4-sulfanyl-1,2-dihydropyrimidine-5-carbonitrile
CAS 2228-22-0C6H5N3OS
5-Acetyl-6-methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one chemical structure, C7H8N2O2S, CAS 90151-12-5
5-Acetyl-6-methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one
CAS 90151-12-5C7H8N2O2S
1-Amino-4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one chemical structure, C4H5N3OS, CAS 58909-37-8
1-Amino-4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one
CAS 58909-37-8C4H5N3OS
1,3,6-Trimethyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one chemical structure, C7H10N2OS, CAS 49786-07-4
1,3,6-Trimethyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one
CAS 49786-07-4C7H10N2OS
4-Imino-6-mercapto-1,3-dimethyl-3,4-dihydropyrimidin-2(1H)-one chemical structure, C6H9N3OS, CAS 28860-32-4
4-Imino-6-mercapto-1,3-dimethyl-3,4-dihydropyrimidin-2(1H)-one
CAS 28860-32-4C6H9N3OS
3-Methyl-4-sulfanylidene-3,4-dihydropyrimidin-2(1H)-one chemical structure, C5H6N2OS, CAS 33268-02-9
3-Methyl-4-sulfanylidene-3,4-dihydropyrimidin-2(1H)-one
CAS 33268-02-9C5H6N2OS
6-Methyl-2-oxo-4-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid chemical structure, C6H6N2O3S, CAS 51622-66-3
6-Methyl-2-oxo-4-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid
CAS 51622-66-3C6H6N2O3S