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Murcko scaffold

Ring system with 4 rings and 25 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
10
With full pages
2
Scaffold SMILES

O=C1CC(Sc2nnnn2-c2ccccc2)C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC(Sc2nnnn2-c2ccccc2)C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

1-(3,4-Dichlorophenyl)-3-(1-phenyltetrazol-5-yl)sulfanylpyrrolidine-2,5-dione chemical structure, C17H11Cl2N5O2S, CAS 543696-82-8
1-(3,4-Dichlorophenyl)-3-(1-phenyltetrazol-5-yl)sulfanylpyrrolidine-2,5-dione
CAS 543696-82-8C17H11Cl2N5O2S
3-[(1-Phenyl-1H-tetrazol-5-yl)sulfanyl]-1-[4-(propan-2-yl)phenyl]pyrrolidine-2,5-dione chemical structure, C20H19N5O2S, CAS 488129-66-4
3-[(1-Phenyl-1H-tetrazol-5-yl)sulfanyl]-1-[4-(propan-2-yl)phenyl]pyrrolidine-2,5-dione
CAS 488129-66-4C20H19N5O2S
1-(4-Ethoxyphenyl)-3-[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]pyrrolidine-2,5-dione chemical structure, C19H17N5O3S, CAS 448914-48-5
1-(4-Ethoxyphenyl)-3-[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]pyrrolidine-2,5-dione
CAS 448914-48-5C19H17N5O3S
1-(4-Nitrophenyl)-3-[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]pyrrolidine-2,5-dione chemical structure, C17H12N6O4S, CAS 488746-48-1
1-(4-Nitrophenyl)-3-[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]pyrrolidine-2,5-dione
CAS 488746-48-1C17H12N6O4S
1-(3,5-Dimethylphenyl)-3-[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]pyrrolidine-2,5-dione chemical structure, C19H17N5O2S, CAS 511515-05-2
1-(3,5-Dimethylphenyl)-3-[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]pyrrolidine-2,5-dione
CAS 511515-05-2C19H17N5O2S
Ethyl 4-{2,5-dioxo-3-[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]pyrrolidin-1-yl}benzoate chemical structure, C20H17N5O4S, CAS 522652-28-4
Ethyl 4-{2,5-dioxo-3-[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]pyrrolidin-1-yl}benzoate
CAS 522652-28-4C20H17N5O4S
1-(3,5-Dichlorophenyl)-3-[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]pyrrolidine-2,5-dione chemical structure, C17H11Cl2N5O2S, CAS 511515-06-3
1-(3,5-Dichlorophenyl)-3-[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]pyrrolidine-2,5-dione
CAS 511515-06-3C17H11Cl2N5O2S
1-(4-Fluoro-3-nitrophenyl)-3-(1-phenyltetrazol-5-yl)sulfanylpyrrolidine-2,5-dione chemical structure, C17H11FN6O4S, CAS 511515-10-9
1-(4-Fluoro-3-nitrophenyl)-3-(1-phenyltetrazol-5-yl)sulfanylpyrrolidine-2,5-dione
CAS 511515-10-9C17H11FN6O4S
3-{[1-(4-Fluorophenyl)-1H-tetrazol-5-yl]sulfanyl}-1-(4-methoxyphenyl)pyrrolidine-2,5-dione chemical structure, C18H14FN5O3S, CAS 577695-90-0
3-{[1-(4-Fluorophenyl)-1H-tetrazol-5-yl]sulfanyl}-1-(4-methoxyphenyl)pyrrolidine-2,5-dione
CAS 577695-90-0C18H14FN5O3S
1-(3-Chlorophenyl)-3-[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]pyrrolidine-2,5-dione chemical structure, C17H12ClN5O2S, CAS 700854-73-5
1-(3-Chlorophenyl)-3-[(1-phenyl-1H-tetrazol-5-yl)sulfanyl]pyrrolidine-2,5-dione
CAS 700854-73-5C17H12ClN5O2S