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Murcko scaffold

Ring system with 6 rings and 24 atoms

66 chemicals on CompoundList share this ring system.

Rings
6
Scaffold atoms
24
Chemicals
66
With full pages
13
Scaffold SMILES

O=C(Nc1ccccc1)C12CC3CC(C1)CC(n1cncn1)(C3)C2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)C12CC3CC(C1)CC(n1cncn1)(C3)C2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 66 chemicals

N-(4-Butylphenyl)-3-(3-chloro-1,2,4-triazol-1-yl)adamantane-1-carboxamide chemical structure, C23H29ClN4O, CAS 445015-52-1
N-(4-Butylphenyl)-3-(3-chloro-1,2,4-triazol-1-yl)adamantane-1-carboxamide
CAS 445015-52-1C23H29ClN4O
3-(3-Chloro-1,2,4-triazol-1-yl)-N-(2-fluoro-5-nitrophenyl)adamantane-1-carboxamide chemical structure, C19H19ClFN5O3, CAS 514839-58-8
3-(3-Chloro-1,2,4-triazol-1-yl)-N-(2-fluoro-5-nitrophenyl)adamantane-1-carboxamide
CAS 514839-58-8C19H19ClFN5O3
3-(3-Bromo-1,2,4-triazol-1-yl)-N-(3,5-dichlorophenyl)adamantane-1-carboxamide chemical structure, C19H19BrCl2N4O, CAS 515831-38-6
3-(3-Bromo-1,2,4-triazol-1-yl)-N-(3,5-dichlorophenyl)adamantane-1-carboxamide
CAS 515831-38-6C19H19BrCl2N4O
3-(3-Bromo-1,2,4-triazol-1-yl)-N-(2-iodophenyl)adamantane-1-carboxamide chemical structure, C19H20BrIN4O, CAS 445015-81-6
3-(3-Bromo-1,2,4-triazol-1-yl)-N-(2-iodophenyl)adamantane-1-carboxamide
CAS 445015-81-6C19H20BrIN4O
N-(5-Fluoro-2-methylphenyl)-3-(3-nitro-1,2,4-triazol-1-yl)adamantane-1-carboxamide chemical structure, C20H22FN5O3, CAS 445016-74-0
N-(5-Fluoro-2-methylphenyl)-3-(3-nitro-1,2,4-triazol-1-yl)adamantane-1-carboxamide
CAS 445016-74-0C20H22FN5O3
Methyl 2-({[3-(3-chloro-1H-1,2,4-triazol-1-yl)-1-adamantyl]carbonyl}amino)-4,5-dimethoxybenzoate chemical structure, C23H27ClN4O5, CAS 445015-75-8
Methyl 2-({[3-(3-chloro-1H-1,2,4-triazol-1-yl)-1-adamantyl]carbonyl}amino)-4,5-dimethoxybenzoate
CAS 445015-75-8C23H27ClN4O5
N-(4-Chloro-2,5-dimethoxyphenyl)-3-(1,2,4-triazol-1-yl)adamantane-1-carboxamide chemical structure, C21H25ClN4O3, CAS 445017-16-3
N-(4-Chloro-2,5-dimethoxyphenyl)-3-(1,2,4-triazol-1-yl)adamantane-1-carboxamide
CAS 445017-16-3C21H25ClN4O3
3-(3-Bromo-1,2,4-triazol-1-yl)-N-[4-(methylsulfamoyl)phenyl]adamantane-1-carboxamide chemical structure, C20H24BrN5O3S, CAS 492429-46-6
3-(3-Bromo-1,2,4-triazol-1-yl)-N-[4-(methylsulfamoyl)phenyl]adamantane-1-carboxamide
CAS 492429-46-6C20H24BrN5O3S
3-(3-Chloro-1,2,4-triazol-1-yl)-N-[4-(difluoromethoxy)-3-methoxyphenyl]adamantane-1-carboxamide chemical structure, C21H23ClF2N4O3, CAS 828287-25-8
3-(3-Chloro-1,2,4-triazol-1-yl)-N-[4-(difluoromethoxy)-3-methoxyphenyl]adamantane-1-carboxamide
CAS 828287-25-8C21H23ClF2N4O3
3-(3-Chloro-1,2,4-triazol-1-yl)-N-[2-(difluoromethoxy)phenyl]adamantane-1-carboxamide chemical structure, C20H21ClF2N4O2, CAS 828287-51-0
3-(3-Chloro-1,2,4-triazol-1-yl)-N-[2-(difluoromethoxy)phenyl]adamantane-1-carboxamide
CAS 828287-51-0C20H21ClF2N4O2
3-(3-Bromo-1,2,4-triazol-1-yl)-N-(2-butylphenyl)adamantane-1-carboxamide chemical structure, C23H29BrN4O, CAS 492429-23-9
3-(3-Bromo-1,2,4-triazol-1-yl)-N-(2-butylphenyl)adamantane-1-carboxamide
CAS 492429-23-9C23H29BrN4O
N-(3,5-Dimethoxyphenyl)-3-(3-nitro-1,2,4-triazol-1-yl)adamantane-1-carboxamide chemical structure, C21H25N5O5, CAS 445022-96-8
N-(3,5-Dimethoxyphenyl)-3-(3-nitro-1,2,4-triazol-1-yl)adamantane-1-carboxamide
CAS 445022-96-8C21H25N5O5
3-(3-Bromo-1,2,4-triazol-1-yl)-N-(5-chloro-2-methylphenyl)adamantane-1-carboxamide chemical structure, C20H22BrClN4O, CAS 515848-03-0
3-(3-Bromo-1,2,4-triazol-1-yl)-N-(5-chloro-2-methylphenyl)adamantane-1-carboxamide
CAS 515848-03-0C20H22BrClN4O
3-(3-Bromo-1H-1,2,4-triazol-1-yl)-N-(2,5-dimethoxyphenyl)-1-adamantanecarboxamide chemical structure, C21H25BrN4O3, CAS 515831-58-0
3-(3-Bromo-1H-1,2,4-triazol-1-yl)-N-(2,5-dimethoxyphenyl)-1-adamantanecarboxamide
CAS 515831-58-0C21H25BrN4O3
3-(3-Bromo-1H-1,2,4-triazol-1-yl)-N-(4-methoxy-2-methylphenyl)-1-adamantanecarboxamide chemical structure, C21H25BrN4O2, CAS 515847-50-4
3-(3-Bromo-1H-1,2,4-triazol-1-yl)-N-(4-methoxy-2-methylphenyl)-1-adamantanecarboxamide
CAS 515847-50-4C21H25BrN4O2
N-[2-Fluoro-5-(trifluoromethyl)phenyl]-3-(1,2,4-triazol-1-yl)adamantane-1-carboxamide chemical structure, C20H20F4N4O, CAS 514837-52-6
N-[2-Fluoro-5-(trifluoromethyl)phenyl]-3-(1,2,4-triazol-1-yl)adamantane-1-carboxamide
CAS 514837-52-6C20H20F4N4O
N-(4-Chloro-2-fluorophenyl)-3-(3-nitro-1,2,4-triazol-1-yl)adamantane-1-carboxamide chemical structure, C19H19ClFN5O3, CAS 514817-47-1
N-(4-Chloro-2-fluorophenyl)-3-(3-nitro-1,2,4-triazol-1-yl)adamantane-1-carboxamide
CAS 514817-47-1C19H19ClFN5O3
N-(3-Bromophenyl)-3-(1,2,4-triazol-1-yl)adamantane-1-carboxamide chemical structure, C19H21BrN4O, CAS 515174-78-4
N-(3-Bromophenyl)-3-(1,2,4-triazol-1-yl)adamantane-1-carboxamide
CAS 515174-78-4C19H21BrN4O
3-(3-Bromo-1,2,4-triazol-1-yl)-N-(2,4-dichlorophenyl)adamantane-1-carboxamide chemical structure, C19H19BrCl2N4O, CAS 514840-99-4
3-(3-Bromo-1,2,4-triazol-1-yl)-N-(2,4-dichlorophenyl)adamantane-1-carboxamide
CAS 514840-99-4C19H19BrCl2N4O
Methyl 4,5-dimethoxy-2-[[3-(1,2,4-triazol-1-yl)adamantane-1-carbonyl]amino]benzoate chemical structure, C23H28N4O5, CAS 444936-39-4
Methyl 4,5-dimethoxy-2-[[3-(1,2,4-triazol-1-yl)adamantane-1-carbonyl]amino]benzoate
CAS 444936-39-4C23H28N4O5
N-(4-Bromophenyl)-3-(3-bromo-1,2,4-triazol-1-yl)adamantane-1-carboxamide chemical structure, C19H20Br2N4O, CAS 445023-30-3
N-(4-Bromophenyl)-3-(3-bromo-1,2,4-triazol-1-yl)adamantane-1-carboxamide
CAS 445023-30-3C19H20Br2N4O
3-(3-Bromo-1H-1,2,4-triazol-1-yl)-N-(3-chloro-4-methoxyphenyl)-1-adamantanecarboxamide chemical structure, C20H22BrClN4O2, CAS 515848-67-6
3-(3-Bromo-1H-1,2,4-triazol-1-yl)-N-(3-chloro-4-methoxyphenyl)-1-adamantanecarboxamide
CAS 515848-67-6C20H22BrClN4O2
N-(2-Acetyl-4,5-dimethoxyphenyl)-3-(3-chloro-1,2,4-triazol-1-yl)adamantane-1-carboxamide chemical structure, C23H27ClN4O4, CAS 444931-53-7
N-(2-Acetyl-4,5-dimethoxyphenyl)-3-(3-chloro-1,2,4-triazol-1-yl)adamantane-1-carboxamide
CAS 444931-53-7C23H27ClN4O4
3-(3-Chloro-1,2,4-triazol-1-yl)-N-(2-fluoro-5-methylphenyl)adamantane-1-carboxamide chemical structure, C20H22ClFN4O, CAS 444937-43-3
3-(3-Chloro-1,2,4-triazol-1-yl)-N-(2-fluoro-5-methylphenyl)adamantane-1-carboxamide
CAS 444937-43-3C20H22ClFN4O