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Murcko scaffold

Ring system with 3 rings and 23 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
9
With full pages
5
Scaffold SMILES

O=C(CSc1nccn(-c2ccccc2)c1=O)NC1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nccn(-c2ccccc2)c1=O)NC1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

2-[4-(3-Chloro-4-fluorophenyl)-3-oxopyrazin-2-yl]sulfanyl-N-cyclopentylacetamide chemical structure, C17H17ClFN3O2S, CAS 899944-00-4
2-[4-(3-Chloro-4-fluorophenyl)-3-oxopyrazin-2-yl]sulfanyl-N-cyclopentylacetamide
CAS 899944-00-4C17H17ClFN3O2S
2-[4-(3-Chloro-4-methoxyphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-cyclopentylacetamide chemical structure, C18H20ClN3O3S, CAS 899944-18-4
2-[4-(3-Chloro-4-methoxyphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-cyclopentylacetamide
CAS 899944-18-4C18H20ClN3O3S
2-{[4-(3-Chloro-4-methylphenyl)-3-oxo-3,4-dihydropyrazin-2-yl]sulfanyl}-N-cyclopentylacetamide chemical structure, C18H20ClN3O2S, CAS 899988-15-9
2-{[4-(3-Chloro-4-methylphenyl)-3-oxo-3,4-dihydropyrazin-2-yl]sulfanyl}-N-cyclopentylacetamide
CAS 899988-15-9C18H20ClN3O2S
N-Cyclopentyl-2-[4-(4-ethoxyphenyl)-3-oxopyrazin-2-yl]sulfanylacetamide chemical structure, C19H23N3O3S, CAS 899945-19-8
N-Cyclopentyl-2-[4-(4-ethoxyphenyl)-3-oxopyrazin-2-yl]sulfanylacetamide
CAS 899945-19-8C19H23N3O3S
N-Cyclopentyl-2-[4-(3,4-difluorophenyl)-3-oxopyrazin-2-yl]sulfanylacetamide chemical structure, C17H17F2N3O2S, CAS 899958-64-6
N-Cyclopentyl-2-[4-(3,4-difluorophenyl)-3-oxopyrazin-2-yl]sulfanylacetamide
CAS 899958-64-6C17H17F2N3O2S
N-Cyclopentyl-2-{[4-(3,4-dimethoxyphenyl)-3-oxo-3,4-dihydropyrazin-2-yl]sulfanyl}acetamide chemical structure, C19H23N3O4S, CAS 899987-53-2
N-Cyclopentyl-2-{[4-(3,4-dimethoxyphenyl)-3-oxo-3,4-dihydropyrazin-2-yl]sulfanyl}acetamide
CAS 899987-53-2C19H23N3O4S
N-Cyclopentyl-2-((4-(3-fluoro-4-methylphenyl)-3-oxo-3,4-dihydropyrazin-2-yl)thio)acetamide chemical structure, C18H20FN3O2S, CAS 900006-75-9
N-Cyclopentyl-2-((4-(3-fluoro-4-methylphenyl)-3-oxo-3,4-dihydropyrazin-2-yl)thio)acetamide
CAS 900006-75-9C18H20FN3O2S
2-((4-(4-Bromophenyl)-3-oxo-3,4-dihydropyrazin-2-yl)thio)-N-cyclopentylacetamide chemical structure, C17H18BrN3O2S, CAS 899759-59-2
2-((4-(4-Bromophenyl)-3-oxo-3,4-dihydropyrazin-2-yl)thio)-N-cyclopentylacetamide
CAS 899759-59-2C17H18BrN3O2S
2-{[4-(3-Chlorophenyl)-3-oxo-3,4-dihydropyrazin-2-yl]sulfanyl}-N-cyclopentylacetamide chemical structure, C17H18ClN3O2S, CAS 895105-83-6
2-{[4-(3-Chlorophenyl)-3-oxo-3,4-dihydropyrazin-2-yl]sulfanyl}-N-cyclopentylacetamide
CAS 895105-83-6C17H18ClN3O2S