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Murcko scaffold

1-(5-Benzofuranyl)piperazine scaffold

26 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
26
With full pages
3
Scaffold SMILES

c1cc2cc(N3CCNCC3)ccc2o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(5-Benzofuranyl)piperazine page
Murcko scaffold c1cc2cc(N3CCNCC3)ccc2o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

5-(Piperazin-1-yl)benzofuran-2-carboxamide chemical structure, C13H15N3O2, CAS 183288-46-2
5-(Piperazin-1-yl)benzofuran-2-carboxamide
CAS 183288-46-2C13H15N3O2
tert-Butyl 4-(benzofuran-5-yl)piperazine-1-carboxylate chemical structure, C17H22N2O3, CAS 479226-00-1
tert-Butyl 4-(benzofuran-5-yl)piperazine-1-carboxylate
CAS 479226-00-1C17H22N2O3
1-(5-Benzofuranyl)piperazine chemical structure, C12H14N2O, CAS 206347-31-1
1-(5-Benzofuranyl)piperazine
CAS 206347-31-1C12H14N2O
1-Piperazinecarboxylic acid, 4-[2-(ethoxycarbonyl)-5-benzofuranyl]-, 1,1-dimethylethyl ester chemical structure, C20H26N2O5, CAS 183288-43-9
1-Piperazinecarboxylic acid, 4-[2-(ethoxycarbonyl)-5-benzofuranyl]-, 1,1-dimethylethyl ester
CAS 183288-43-9C20H26N2O5
tert-Butyl 4-(2-carbamoylbenzofuran-5-yl)piperazine-1-carboxylate chemical structure, C18H23N3O4, CAS 183288-44-0
tert-Butyl 4-(2-carbamoylbenzofuran-5-yl)piperazine-1-carboxylate
CAS 183288-44-0C18H23N3O4
Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate hydrochloride chemical structure, C15H19ClN2O3, CAS 765935-67-9
Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate hydrochloride
CAS 765935-67-9C15H19ClN2O3
Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate chemical structure, C15H18N2O3, CAS 163521-20-8
Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate
CAS 163521-20-8C15H18N2O3
1-(1,1-Dimethylethyl) 4-(2-carboxy-5-benzofuranyl)-1-piperazinecarboxylate chemical structure, C18H22N2O5, CAS 1192170-26-5
1-(1,1-Dimethylethyl) 4-(2-carboxy-5-benzofuranyl)-1-piperazinecarboxylate
CAS 1192170-26-5C18H22N2O5
5-Piperazin-1-yl-1-benzofuran-2-carbonitrile chemical structure, C13H13N3O, CAS 765936-10-5
5-Piperazin-1-yl-1-benzofuran-2-carbonitrile
CAS 765936-10-5C13H13N3O
1-(2-Hydroxymethylbenzofuran-5-yl)piperazine chemical structure, C13H16N2O2, CAS 163521-15-1
1-(2-Hydroxymethylbenzofuran-5-yl)piperazine
CAS 163521-15-1C13H16N2O2
5-(Piperazin-1-yl)benzofuran-2-carboxylic acid chemical structure, C13H14N2O3, CAS 183288-47-3
5-(Piperazin-1-yl)benzofuran-2-carboxylic acid
CAS 183288-47-3C13H14N2O3
5-(Piperazin-1-yl)benzofuran-2-carboxamide hydrochloride chemical structure, C13H16ClN3O2, CAS 913730-87-7
5-(Piperazin-1-yl)benzofuran-2-carboxamide hydrochloride
CAS 913730-87-7C13H16ClN3O2
1-(1,1-Dimethylethyl) 4-(4-bromo-2-carboxy-5-benzofuranyl)-1-piperazinecarboxylate chemical structure, C18H21BrN2O5, CAS 1192170-24-3
1-(1,1-Dimethylethyl) 4-(4-bromo-2-carboxy-5-benzofuranyl)-1-piperazinecarboxylate
CAS 1192170-24-3C18H21BrN2O5
tert-Butyl 4-(4-bromo-2-(ethoxycarbonyl)benzofuran-5-yl)piperazine-1-carboxylate chemical structure, C20H25BrN2O5, CAS 1192170-25-4
tert-Butyl 4-(4-bromo-2-(ethoxycarbonyl)benzofuran-5-yl)piperazine-1-carboxylate
CAS 1192170-25-4C20H25BrN2O5
1-Benzofuran-5-yl-3-methyl-piperazine chemical structure, C13H16N2O, CAS 866785-95-7
1-Benzofuran-5-yl-3-methyl-piperazine
CAS 866785-95-7C13H16N2O
tert-Butyl 4-(2-(ethoxycarbonyl)-4-methylbenzofuran-5-yl)piperazine-1-carboxylate chemical structure, C21H28N2O5, CAS 1192172-70-5
tert-Butyl 4-(2-(ethoxycarbonyl)-4-methylbenzofuran-5-yl)piperazine-1-carboxylate
CAS 1192172-70-5C21H28N2O5
2Nku4H7jwa chemical structure, C15H20Cl2N2O3, CAS 1469427-44-8
2Nku4H7jwa
CAS 1469427-44-8C15H20Cl2N2O3
5-(4-Formyl-1-piperazinyl)-2-benzofurancarboxamide chemical structure, C14H15N3O3, CAS 1602487-82-0
5-(4-Formyl-1-piperazinyl)-2-benzofurancarboxamide
CAS 1602487-82-0C14H15N3O3
Methyl 5-(piperazin-1-yl)benzofuran-2-carboxylate chemical structure, C14H16N2O3, CAS 1186225-86-4
Methyl 5-(piperazin-1-yl)benzofuran-2-carboxylate
CAS 1186225-86-4C14H16N2O3
5-(1-Piperazinyl)-2-benzofurancarboxylic acid ethyl ester dihydrochloride hydrate chemical structure, C15H22Cl2N2O4, CAS 1422956-31-7
5-(1-Piperazinyl)-2-benzofurancarboxylic acid ethyl ester dihydrochloride hydrate
CAS 1422956-31-7C15H22Cl2N2O4
1-(3-Methyl-1-benzofuran-5-yl)piperazine chemical structure, C13H16N2O, CAS 1518177-45-1
1-(3-Methyl-1-benzofuran-5-yl)piperazine
CAS 1518177-45-1C13H16N2O
Butyl 5-(1-piperazinyl)-2-benzofurancarboxylate chemical structure, C17H22N2O3, CAS 1426915-64-1
Butyl 5-(1-piperazinyl)-2-benzofurancarboxylate
CAS 1426915-64-1C17H22N2O3
5-(4-Nitrosopiperazin-1-yl)benzofuran-2-carboxylic Acid Ethyl Ester chemical structure, C15H17N3O4, CAS 2512217-82-0
5-(4-Nitrosopiperazin-1-yl)benzofuran-2-carboxylic Acid Ethyl Ester
CAS 2512217-82-0C15H17N3O4
Ethyl 5-(4-(2-((chloromethyl)amino)ethyl)piperazin-1-yl)benzofuran-2-carboxylate chemical structure, C18H24ClN3O3, CAS 2044702-70-5
Ethyl 5-(4-(2-((chloromethyl)amino)ethyl)piperazin-1-yl)benzofuran-2-carboxylate
CAS 2044702-70-5C18H24ClN3O3