Murcko scaffold
5-Phenylpyrazolo[1,5-a]pyrimidine scaffold
299 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 15
- Chemicals
- 299
- With full pages
- 45
Scaffold SMILES
c1ccc(-c2ccn3nccc3n2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 299 chemicals
![5-Phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide chemical structure, C14H9F3N4O, CAS 300717-56-0](/s/JBEUBATVQBGMMP-UHFFFAOYSA-N.svg)
5-Phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
CAS 300717-56-0C14H9F3N4O
![5-(3,4-Dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C16H12F3N3O4, CAS 333761-27-6](/s/DLJWDFMOTFUAGN-UHFFFAOYSA-N.svg)
5-(3,4-Dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS 333761-27-6C16H12F3N3O4
![Methyl 5-(4-fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C15H9F4N3O2, CAS 313388-04-4](/s/XOEPHPISEVENKE-UHFFFAOYSA-N.svg)
Methyl 5-(4-fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 313388-04-4C15H9F4N3O2
![5-(3-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C15H10F3N3O3, CAS 797809-13-3](/s/XRAFVTBHXRPEMD-UHFFFAOYSA-N.svg)
5-(3-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS 797809-13-3C15H10F3N3O3
![5-Phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid chemical structure, C14H8F3N3O2, CAS 294194-47-1](/s/ATBJQBRIAPZDIC-UHFFFAOYSA-N.svg)
5-Phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
CAS 294194-47-1C14H8F3N3O2
![Ethyl 7-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C16H15N3O2, CAS 140706-36-1](/s/IAYAKQRHDBYXSS-UHFFFAOYSA-N.svg)
Ethyl 7-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 140706-36-1C16H15N3O2
![5-(4-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide chemical structure, C15H11F3N4O2, CAS 312633-97-9](/s/UFIHWUMYHCHBPB-UHFFFAOYSA-N.svg)
5-(4-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
CAS 312633-97-9C15H11F3N4O2
![5-Phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide chemical structure, C14H10F3N5O, CAS 329222-73-3](/s/OKBFZOQFFKBUAJ-UHFFFAOYSA-N.svg)
5-Phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide
CAS 329222-73-3C14H10F3N5O
![Methyl 5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C15H10F3N3O2, CAS 312635-18-0](/s/FXTYXRKGGVCCSD-UHFFFAOYSA-N.svg)
Methyl 5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 312635-18-0C15H10F3N3O2
![Ethyl 5-(4-ethoxyphenyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C18H19N3O3, CAS 313249-36-4](/s/SOLSBHWSYVKWFX-UHFFFAOYSA-N.svg)
Ethyl 5-(4-ethoxyphenyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 313249-36-4C18H19N3O3
![5-Phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C14H7F3N4, CAS 296796-42-4](/s/MJGNWUULORTGBF-UHFFFAOYSA-N.svg)
5-Phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 296796-42-4C14H7F3N4
![5-(4-Propan-2-yloxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C17H13F3N4O, CAS 693814-19-6](/s/FCZVLDLRBZCXOP-UHFFFAOYSA-N.svg)
5-(4-Propan-2-yloxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 693814-19-6C17H13F3N4O
![Ethyl 5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C16H12F3N3O2, CAS 312635-19-1](/s/DQWUKBFAOSIKEW-UHFFFAOYSA-N.svg)
Ethyl 5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate
CAS 312635-19-1C16H12F3N3O2
![5-(4-Ethoxyphenyl)-7-methylpyrazolo[1,5-a]pyrimidine-2-carboxamide chemical structure, C16H16N4O2, CAS 313387-50-7](/s/BXIZJGZAEAKYFL-UHFFFAOYSA-N.svg)
5-(4-Ethoxyphenyl)-7-methylpyrazolo[1,5-a]pyrimidine-2-carboxamide
CAS 313387-50-7C16H16N4O2
![5-(4-Chlorophenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C14H9ClF3N3, CAS 677311-39-6](/s/RJVIWVBIHYSUFC-UHFFFAOYSA-N.svg)
5-(4-Chlorophenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS 677311-39-6C14H9ClF3N3
![5-(4-Methoxyphenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C15H12F3N3O, CAS 438222-36-7](/s/TUGNTIFUYCUODJ-UHFFFAOYSA-N.svg)
5-(4-Methoxyphenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS 438222-36-7C15H12F3N3O
![Methyl 5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylate chemical structure, C16H12F3N3O2, CAS 5815-79-2](/s/ZTRQPFFLBBJSSH-UHFFFAOYSA-N.svg)
Methyl 5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS 5815-79-2C16H12F3N3O2
![5-(4-Chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid chemical structure, C14H7ClF3N3O2, CAS 312922-12-6](/s/PHWXMWUQBLSUBM-UHFFFAOYSA-N.svg)
5-(4-Chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
CAS 312922-12-6C14H7ClF3N3O2
![2-Methyl-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C14H10F3N3, CAS 428833-40-3](/s/KBXGXKFVWZXAMV-UHFFFAOYSA-N.svg)
2-Methyl-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS 428833-40-3C14H10F3N3
![Methyl 5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylate chemical structure, C15H10F3N3O2, CAS 294194-48-2](/s/LBMPDECEGMPFNZ-UHFFFAOYSA-N.svg)
Methyl 5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS 294194-48-2C15H10F3N3O2
![2-Methyl-5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C15H12F3N3, CAS 626207-50-9](/s/MNWCLDFGVKEPBS-UHFFFAOYSA-N.svg)
2-Methyl-5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS 626207-50-9C15H12F3N3
![5-(4-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid chemical structure, C15H10F3N3O3, CAS 310451-80-0](/s/ZIZDJEVOZFFKAS-UHFFFAOYSA-N.svg)
5-(4-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
CAS 310451-80-0C15H10F3N3O3
![Methyl 7-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-2-carboxylate chemical structure, C15H13N3O2, CAS 333396-14-8](/s/QPCZVFDRLFBYKQ-UHFFFAOYSA-N.svg)
Methyl 7-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS 333396-14-8C15H13N3O2
7-Methyl-5-phenylpyrazolo(1,5-a)pyrimidine-2-carboxylic acid
CAS 312922-05-7C14H11N3O2
- Ethyl 7-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-2-carboxylate309739-41-1C16H15N3O2
- 5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid310451-82-2C14H7F4N3O2
- 6-(Ethoxycarbonyl)-7-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-2-carboxylic acid313249-40-0C17H15N3O4
- 5-(4-Chlorophenyl)-7-methylpyrazolo[1,5-a]pyrimidine-2-carboxylic acid333765-72-3C14H10ClN3O2
- 5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid310451-83-3C14H7F4N3O2
- 5-(4-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid333761-72-1C15H10F3N3O3
- 5-(4-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide333761-73-2C15H11F3N4O2
- 3-Chloro-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid299405-80-4C14H7ClF3N3O2
- 5-Phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid312635-16-8C14H8F3N3O2
- 7-Methyl-5-phenylpyrazolo[1,5-a]pyrimidine-2-carboxamide312634-71-2C14H12N4O
- 7-Methyl-5-phenyl-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid isopropyl ester5025-20-7C17H17N3O2
- Ethyl 5-(4-fluorophenyl)-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate313389-29-6C16H14FN3O2
- Ethyl 7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate492433-50-8C17H15F2N3O3
- 7-Methyl-5-phenylpyrazolo[1,5-a]pyrimidine-3-carbohydrazide438220-41-8C14H13N5O
- 5-(4-Chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile512818-22-3C14H6ClF3N4
- 5-(4-Methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile512818-00-7C15H9F3N4O
- 5-(3,4-Dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine438233-94-4C15H12F3N3
- 5-(4-Chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine438233-60-4C13H7ClF3N3
- 5-(4-Isopropylphenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine438233-23-9C17H16F3N3
- 5-(4-Fluorophenyl)-7-methylpyrazolo[1,5-a]pyrimidine-2-carboxylic acid332375-37-8C14H10FN3O2
- 5-(4-Ethoxyphenyl)-7-methylpyrazolo[1,5-a]pyrimidine-2-carboxylic acid354542-40-8C16H15N3O3
- Ethyl 5-(P-tolyl)-7-(trifluoromethyl)pyrazolo[1,5-A]pyrimidine-3-carboxylate351989-80-5C17H14F3N3O2
- 2-Methyl-5-(4-propan-2-yloxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine693795-97-0C17H16F3N3O
- 7-(Difluoromethyl)-5-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid712319-09-0C14H8F3N3O2
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